Journal
JOURNAL OF FUNGI
Volume 7, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/jof7060464
Keywords
brown rot; secreted proteins; CAZome; secondary metabolism; sexual reproduction
Categories
Funding
- Spanish Government through Ministry of Economy, Industry and Competitiveness (MINECO) [AGL2017-84389]
- CERCA Programme/Generalitat de Catalunya
- Spanish Ministry of Science and Innovation [PGC2018-099921-B-I00]
- Catalan Research Agency (AGAUR) [SGR423]
- European Union's Horizon 2020 research and innovation programme [ERC-2016-724173, 741964]
- Gordon and Betty Moore Foundation [GBMF9742]
- Instituto de Salud Carlos III (INB) [PT17/0009/0023ISCIII-SGEFI/ERDF]
- programme Beatriu de Pinos - Secretary of Universities and Research (Government of Catalonia)
- Horizon 2020 programme of research and innovation of the European Union under the Marie Sklodowska-Curie grant [801370]
- Marie Curie Actions (MSCA) [741964] Funding Source: Marie Curie Actions (MSCA)
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Brown rot, caused by Monilinia spp., is a significant disease in stone fruits and apples. Future sustainable strategies to control this disease may involve studying genomic variation among Monilinia spp. Comparative genomic analyses provide insights into the differences that underlie interactions with host plants.
Brown rot, caused by Monilinia spp., is among the most important diseases in stone fruits, and some pome fruits (mainly apples). This disease is responsible for significant yield losses, particularly in stone fruits, when weather conditions favorable for disease development appear. To achieve future sustainable strategies to control brown rot on fruit, one potential approach will be to characterize genomic variation among Monilinia spp. to define, among others, the capacity to infect fruit in this genus. In the present work, we performed genomic and phylogenomic comparisons of five Monilinia species and inferred differences in numbers of secreted proteins, including CAZy proteins and other proteins important for virulence. Duplications specific to Monilinia were sparse and, overall, more genes have been lost than gained. Among Monilinia spp., low variability in the CAZome was observed. Interestingly, we identified several secondary metabolism clusters based on similarity to known clusters, and among them was a cluster with homology to pyriculol that could be responsible for the synthesis of chloromonilicin. Furthermore, we compared sequences of all strains available from NCBI of these species to assess their MAT loci and heterokaryon compatibility systems. Our comparative analyses provide the basis for future studies into understanding how these genomic differences underlie common or differential abilities to interact with the host plant.
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