Related references
Note: Only part of the references are listed.The Role of Autophagy in Glaucomatous Optic Neuropathy
Annagrazia Adornetto et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Bioenergetic shift and actin cytoskeleton remodelling as acute vascular adaptive mechanisms to angiotensin II in murine retina and ophthalmic artery
Natarajan Perumal et al.
REDOX BIOLOGY (2020)
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2
Nathalie Escande-Beillard et al.
NEURON (2020)
Impairment of the mitochondrial one-carbon metabolism enzyme SHMT2 causes a novel brain and heart developmental syndrome
Angels Garcia-Cazorla et al.
ACTA NEUROPATHOLOGICA (2020)
Cancer proteome and metabolite changes linked to SHMT2
Jiefei Tong et al.
PLOS ONE (2020)
Progress in research on the role of Omi/HtrA2 in neurological diseases
Xiao Juan Su et al.
REVIEWS IN THE NEUROSCIENCES (2019)
Sample Preparation for Mass-spectrometry-based Proteomics Analysis of Ocular Microvessels
Natarajan Perumal et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2019)
Inhibition of HtrA2 alleviated dextran sulfate sodium (DSS)-induced colitis by preventing necroptosis of intestinal epithelial cells
Chong Zhang et al.
CELL DEATH & DISEASE (2019)
Alzheimer's Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in Drosophila
James P. Higham et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
Yingyao Zhou et al.
NATURE COMMUNICATIONS (2019)
Rho-kinase inhibitors in the management of glaucoma
Emanuela Berrino et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2019)
Synthetic Polyclonal-Derived CDR Peptides as an Innovative Strategy in Glaucoma Therapy
Carsten Schmelter et al.
JOURNAL OF CLINICAL MEDICINE (2019)
Label-Free Immunoprecipitation Mass Spectrometry Workflow for Large-scale Nuclear Interactome Profiling
Steven E. Guard et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2019)
Increased Active OMI/HTRA2 Serine Protease Displays a Positive Correlation with Cholinergic Alterations in the Alzheimer's Disease Brain
Taher Darreh-Shori et al.
MOLECULAR NEUROBIOLOGY (2019)
The PRIDE database and related tools and resources in 2019: improving support for quantification data
Yasset Perez-Riverol et al.
NUCLEIC ACIDS RESEARCH (2019)
Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs
Denise R. Minton et al.
MOLECULAR CELL (2018)
Overexpression of SNX3 Decreases Amyloid-β Peptide Production by Reducing Internalization of Amyloid Precursor Protein
Shaohua Xu et al.
NEURODEGENERATIVE DISEASES (2018)
Rho Kinase Inhibitors as a Novel Treatment for Glaucoma and Ocular Hypertension
Angelo P. Tanna et al.
OPHTHALMOLOGY (2018)
Distinct functional roles of Vps41-mediated neuroprotection in Alzheimer's and Parkinson's disease models of neurodegeneration
Edward F. Griffin et al.
HUMAN MOLECULAR GENETICS (2018)
SHMT2 Overexpression Predicts Poor Prognosis in Intrahepatic Cholangiocarcinoma
Shanglei Ning et al.
GASTROENTEROLOGY RESEARCH AND PRACTICE (2018)
Comparison of Two Solid-Phase Extraction (SPE) Methods for the Identification and Quantification of Porcine Retinal Protein Markers by LC-MS/MS
Carsten Schmelter et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Cdc42 Regulates Neuronal Polarity during Cerebellar Axon Formation and Glial-Guided Migration
Eve-Ellen Govek et al.
ISCIENCE (2018)
Sorting nexin 3 mutation impairs development and neuronal function in Caenorhabditis elegans
Neide Vieira et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Serine catabolism is essential to maintain mitochondrial respiration in mammalian cells
Stephanie Lucas et al.
LIFE SCIENCE ALLIANCE (2018)
Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function
Mei-Chin Lee et al.
HUMAN MOLECULAR GENETICS (2017)
Peptides of the variable IgG domain as potential biomarker candidates in primary open-angle glaucoma (POAG)
Carsten Schmelter et al.
HUMAN MOLECULAR GENETICS (2017)
Ugi Reaction-Derived α-Acyl Aminocarboxamides Bind to Phosphatidylinositol 3-Kinase-Related Kinases, Inhibit HSF1-Dependent Heat Shock Response, and Induce Apoptosis in Multiple Myeloma Cells
Matthias Bach et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Elevated Intraocular Pressure Induces Amyloid-beta Deposition and Tauopathy in the Lateral Geniculate Nucleus in a Monkey Model of Glaucoma
Zhichao Yan et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2017)
Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome
Sandra Ammann et al.
BLOOD (2016)
Structural Mechanism for Cargo Recognition by the Retromer Complex
Maria Lucas et al.
CELL (2016)
Neuroprotective effects of antibodies on retinal ganglion cells in an adolescent retina organ culture
Katharina Bell et al.
JOURNAL OF NEUROCHEMISTRY (2016)
Autophagy in glaucoma: Crosstalk with apoptosis and its implications
Yao Wang et al.
BRAIN RESEARCH BULLETIN (2015)
Extracellular matrix in the trabecular meshwork: Intraocular pressure regulation and dysregulation in glaucoma
Janice A. Vranka et al.
EXPERIMENTAL EYE RESEARCH (2015)
Characterization of human reflex tear proteome reveals high expression of lacrimal proline-rich protein 4 (PRR4)
Natarajan Perumal et al.
PROTEOMICS (2015)
Dexamethasone Increases Cdc42 Expression in Human TM-1 Cells
Xuan Qiu et al.
CURRENT EYE RESEARCH (2015)
Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish
Soo Young Choi et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2015)
Clearance of misfolded and aggregated proteins by aggrephagy and implications for aggregation diseases
Juha M. T. Hyttinen et al.
AGEING RESEARCH REVIEWS (2014)
Characterization of lacrimal proline-rich protein 4 (PRR4) in human tear proteome
Natarajan Perumal et al.
PROTEOMICS (2014)
Rho family GTPases: key players in neuronal development neuronal survival, and neurodegeneration
Trisha R. Stankiewicz et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
A novel role for the mitochondrial HTRA2/OMI protease in aging
Seokwon Kang et al.
AUTOPHAGY (2013)
14-3-3 protein targets misfolded chaperone-associated proteins to aggresomes
Zhe Xu et al.
JOURNAL OF CELL SCIENCE (2013)
Allosteric Regulation of Serine Protease HtrA2 through Novel Non-Canonical Substrate Binding Pocket
Pruthvi Raj Bejugam et al.
PLOS ONE (2013)
CDC42 Is Required for Tissue Lamination and Cell Survival in the Mouse Retina
Severin Reinhard Heynen et al.
PLOS ONE (2013)
DAVID-WS: a stateful web service to facilitate gene/protein list analysis
Xiaoli Jiao et al.
BIOINFORMATICS (2012)
Cdc42: An important regulator of neuronal morphology
Chen Chen et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)
Reducing Amyloid-Related Alzheimer's Disease Pathogenesis by a Small Molecule Targeting Filamin A
Hoau-Yan Wang et al.
JOURNAL OF NEUROSCIENCE (2012)
Functional Analysis of VPS41-Mediated Neuroprotection in Caenorhabditis elegans and Mammalian Models of Parkinson's Disease
Adam J. Harrington et al.
JOURNAL OF NEUROSCIENCE (2012)
HtrA2 deficiency causes mitochondrial uncoupling through the F1F0-ATP synthase and consequent ATP depletion
H. Plun-Favreau et al.
CELL DEATH & DISEASE (2012)
Amyloid Precursor Protein Processing and Alzheimer's Disease
Richard J. O'Brien et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 34 (2011)
Altered enzymatic activity and allele frequency of OMI/HTRA2 in Alzheimer's disease
Marie Westerlund et al.
FASEB JOURNAL (2011)
Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment
Juergen Cox et al.
JOURNAL OF PROTEOME RESEARCH (2011)
Advances in porcine genomics and proteomics-a toolbox for developing the pig as a model organism for molecular biomedical research
Emoke Bendixen et al.
BRIEFINGS IN FUNCTIONAL GENOMICS (2010)
Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases
B. Li et al.
CELL DEATH AND DIFFERENTIATION (2010)
HtrA proteins as targets in therapy of cancer and other diseases
Dorota Zurawa-Janicka et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2010)
Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response
N. Moisoi et al.
CELL DEATH AND DIFFERENTIATION (2009)
Altered retinal cell differentiation in the AP-3 delta mutant (Mocha) mouse
Mark Baguma-Nibasheka et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2009)
The mitochondrial serine protease HtrA2/Omi: an overview
L. Vande Walle et al.
CELL DEATH AND DIFFERENTIATION (2008)
Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies
Lynn Bedford et al.
JOURNAL OF NEUROSCIENCE (2008)
Accurate Inclusion Mass Screening A BRIDGE FROM UNBIASED DISCOVERY TO TARGETED ASSAY DEVELOPMENT FOR BIOMARKER VERIFICATION
Jacob D. Jaffe et al.
MOLECULAR & CELLULAR PROTEOMICS (2008)
Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain
Yingnan Zhang et al.
PROTEIN SCIENCE (2007)
Inhibition of HtrA2/Omi ameliorates heart dysfunction following ischemia/reperfusion injury in rat heart in vivo
Md. Shenuarin Bhuiyan et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Neuronal and non-neuronal functions of the AP-3 sorting machinery
Karen Newell-Litwa et al.
JOURNAL OF CELL SCIENCE (2007)
The serine protease Omi/HtrA2 is involved in XIAP cleavage and in neuronal cell death following focal cerebral ischemia/reperfusion
J. Althaus et al.
NEUROCHEMISTRY INTERNATIONAL (2007)
Proteome-wide identification of HtrA2/Omi substrates
Lieselotte Vande Walle et al.
JOURNAL OF PROTEOME RESEARCH (2007)
The protease inhibitor Ucf-101 induces cellular responses independently of its known target, HtrA2/Omi
K. Klupsch et al.
CELL DEATH AND DIFFERENTIATION (2006)
Autocatalytic processing of HtrA2/Omi is essential for induction of caspase-dependent cell death through antagonizing XIAP
YM Seong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi
LM Martins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice
JM Jones et al.
NATURE (2003)
Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2
L Cilenti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of Omi/HtrA-2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
R Hegde et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Human Nck-associated protein1 and its binding protein affect the metabolism of beta-amyloid precursor protein with Swedish mutation
A Yamamoto et al.
NEUROSCIENCE LETTERS (2001)
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
Y Suzuki et al.
MOLECULAR CELL (2001)
Isolation of hNap1BP which interacts with human Nap1 (NCKAP1) whose expression is down-regulated in Alzheimer's disease
A Yamamoto et al.
GENE (2001)
Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia
L Faccio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)