Journal
ASIAN JOURNAL OF PSYCHIATRY
Volume 60, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.ajp.2021.102625
Keywords
Obsessive-compulsive disorder; Transcranial direct current stimulation; Case series
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Funding
- Wellcome trust/DBT India Alliance Intermediate fellowship [IA/CPHI/16/1/502662]
- Life Science Research Board Grant [DG TM/TM/LSRB/GIA/17-18/197]
- Wellcome Trust-DBT India Alliance Early Career Fellowship grant [IA/CPHE/18/1/503956]
- Department of Science and Technology, Government of India [DST/SJF/LSA-02/2014-15]
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The study indicates that transcranial direct current stimulation may have beneficial effects on some patients with treatment-resistant OCD, with approximately 28% of patients showing at least partial response after 10-20 sessions of treatment.
Objective: The present study is a large case series evaluating the benefits of transcranial direct current stimulation (tDCS) in treatment-resistant obsessive compulsive disorder (OCD). Methods: We reviewed the charts of 32 patients with treatment-resistant OCD who received 10-20 sessions of anodal pre-SMA tDCS. Results: Overall, 9 (28 %) showed at least partial response to tDCS at the end of 10-20 sessions [responders = 8 (25 %), partial responders = 1 (3%)]. Two out of three partial responders at the end of 10 sessions had response at the end of 20 sessions. Conclusions: tDCS may benefit a proportion of patients with treatment-resistant OCD.
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