4.6 Article

A Personalized Medical Decision Support System Based on Explainable Machine Learning Algorithms and ECC Features: Data from the Real World

Journal

DIAGNOSTICS
Volume 11, Issue 9, Pages -

Publisher

MDPI
DOI: 10.3390/diagnostics11091677

Keywords

case-based reasoning; personalized recommendations; machine learning; external features of cases; physician adoption

Funding

  1. National Natural Science Foundation of China (NSFC) [71771077, 72071063, 62111530056]
  2. Fundamental Research Funds for the Central Universities [PA2020GDKC0020]
  3. Anhui Provincial Key Research and Development Plan [202004h07020016]

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This study focuses on the impact of external case characteristics on the personalized medical decision support system for breast cancer diagnosis. By incorporating external features into the case-based reasoning framework, the accuracy of the system is significantly improved.
Artificial intelligence can help physicians improve the accuracy of breast cancer diagnosis. However, the effectiveness of AI applications is limited by doctors' adoption of the results recommended by the personalized medical decision support system. Our primary purpose is to study the impact of external case characteristics (ECC) on the effectiveness of the personalized medical decision support system for breast cancer assisted diagnosis (PMDSS-BCAD) in making accurate recommendations. Therefore, we designed a novel comprehensive framework for case-based reasoning (CBR) that takes the impact of external features of cases into account, made use of the naive Bayes and k-nearest neighbor (KNN) algorithms (CBR-ECC), and developed a PMDSS-BCAD system by using the CBR-ECC model and external features as system components. Under the new case-based reasoning framework, the accuracy of the combined model of naive Bayes and KNN with an optimal K value of 2 is 99.40%. Moreover, in a real hospital scenario, users rated the PMDSS-BCAD system, which takes into account the external characteristics of the case, better than the original personalized system. These results suggest that PMDSS-BCD can not only provide doctors with more personalized and accurate results for auxiliary diagnosis, but also improve doctors' trust in the results, so as to encourage doctors to adopt the results recommended by the personalized system.

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