Cross talk between complete blood count and progression of type II diabetes mellitus

Background: Diabetes mellitus (DM) is a chronic disease that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. The most common type is type II diabetes and is characterized by insulin resistance or relative insulin deficiency. Objectives: This study was performed to discover whether Complte blood count is a suitable indicator for development of type II diabetes complications. Methods: 137 type II diabetic patients with high blood glucose level were included in this study and their complete blood count was recorded. Demographic and laboratory data were also noted. Result: WBC, Hb, Hematocrit, MCH had abnormal values. As the results of this study show, higher leukocyte counts was correlated with uncontrolled diabetes. Accompanied by other markers, chronic inflammation that can be shown by this factor could be related to pathogenesis and the progression of these diabetes-related complications. Conclusion: Complete blood count test could be considered as an appropriate clinical examination for early diagnosis and prevention of microvascular and macrovascular complications thus reducing morbidity and mortality from diabetes mellitus. (C) 2021 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.

Automated summary

The study suggests that complete blood count can serve as an indicator for the development of type II diabetes complications, with a correlation between higher leukocyte counts and uncontrolled diabetes. This factor may be related to chronic inflammation and the progression of diabetes-related complications.