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You Are What You Eat: Application of Metabolomics Approaches to Advance Nutrition Research

Journal

FOODS
Volume 10, Issue 6, Pages -

Publisher

MDPI
DOI: 10.3390/foods10061249

Keywords

metabolomics; NMR; MS; food; nutrition

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The relationship between health and nutrition is closely linked, with poor nutrition potentially leading to various metabolic diseases. Metabolomics, as an emerging field of science, has broad research applications and potential for further advancement.
A healthy condition is defined by complex human metabolic pathways that only function properly when fully satisfied by nutritional inputs. Poor nutritional intakes are associated with a number of metabolic diseases, such as diabetes, obesity, atherosclerosis, hypertension, and osteoporosis. In recent years, nutrition science has undergone an extraordinary transformation driven by the development of innovative software and analytical platforms. However, the complexity and variety of the chemical components present in different food types, and the diversity of interactions in the biochemical networks and biological systems, makes nutrition research a complicated field. Metabolomics science is an -omic, joining proteomics, transcriptomics, and genomics in affording a global understanding of biological systems. In this review, we present the main metabolomics approaches, and highlight the applications and the potential for metabolomics approaches in advancing nutritional food research.

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