Journal
PATHOGENS
Volume 10, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/pathogens10060651
Keywords
West Nile virus; Usutu virus; mosquito-borne infections; human
Categories
Funding
- Ministry of Health of the Czech Republic [NV19-09-00036]
- Ministry of Health, Czech Republic-conceptual development of research organization (FNBr) [65269705]
- Veterinary Research Institute [RVO: RO 0518]
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The study presented epidemiological, clinical, and laboratory findings of five Czech patients diagnosed with autochthonous mosquito-borne diseases, including four with confirmed West Nile virus (WNV) infections and one with Usutu virus (USUV) infection, from July to October 2018. It documented the first human outbreak caused by WNV lineage 2 in the Czech Republic, as well as the first neuroinvasive human disease caused by USUV, indicating the simultaneous circulation of WNV and USUV in the country.
We present epidemiological, clinical and laboratory findings of five Czech patients diagnosed with autochthonous mosquito-borne disease-four patients with confirmed West Nile virus (WNV) and one patient with Usutu virus (USUV) infections, from July to October 2018, including one fatal case due to WNV. This is the first documented human outbreak caused by WNV lineage 2 in the Czech Republic and the first record of a neuroinvasive human disease caused by USUV, which illustrates the simultaneous circulation of WNV and USUV in the country.
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