Related references
Note: Only part of the references are listed.Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
Mathieu Bourdenx et al.
CELL (2021)
Activation of TREM-1 induces endoplasmic reticulum stress through IRE-1α/XBP-1s pathway in murine macrophages
Liang Dong et al.
MOLECULAR IMMUNOLOGY (2021)
PSMB10, the last immunoproteasome gene missing for PRAAS
Guillaume Sarrabay et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)
Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging
Shuai Ma et al.
CELL (2020)
Physical Activity and Diet Shape the Immune System during Aging
Christopher Weyh et al.
NUTRIENTS (2020)
The Calcineurin-TFEB-p62 Pathway Mediates the Activation of Cardiac Macroautophagy by Proteasomal Malfunction
Bo Pan et al.
CIRCULATION RESEARCH (2020)
Investigating AKT activation and autophagy in immunoproteasome-deficient retinal cells
Md. Razaul Karim et al.
PLOS ONE (2020)
Autophagic receptor p62 protects against glycation-derived toxicity and enhances viability
Gemma Aragones et al.
AGING CELL (2020)
Age-Related Decline in Expression of Molecular Chaperones Induces Endoplasmic Reticulum Stress and Chondrocyte Apoptosis in Articular Cartilage
Li Tan et al.
AGING AND DISEASE (2020)
Immunoproteasome activation enables human TRIM5α restriction of HIV-1
Jose M. Jimenez-Guardeno et al.
NATURE MICROBIOLOGY (2019)
Novel proteasome assembly chaperone mutations in PSMG2/PAC2 cause the autoinflammatory interferonopathy CANDLE/PRAAS4
Adriana A. de Jesus et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)
Recent advances in the structural and mechanistic aspects of Hsp70 molecular chaperones
Matthias P. Mayer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Regulation of Proteasome Activity by (Post-)transcriptional Mechanisms
Suzan Kors et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2019)
Heterozygous Truncating Variants in POMP Escape Nonsense-Mediated Decay and Cause a Unique Immune Dysregulatory Syndrome
M. Cecilia Poli et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2018)
Infiltrating macrophages contribute to age-related neuroinflammation in C57/BL6 mice
H. Wolfe et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2018)
Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α
Denisse Sepulveda et al.
MOLECULAR CELL (2018)
The Unfolded Protein Response and Cell Fate Control
Claudio Hetz et al.
MOLECULAR CELL (2018)
Aging Hallmarks: The Benefits of Physical exercise
Alexandre Rebelo-Marques et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Origin of the Autophagosome Membrane in Mammals
Yun Wei et al.
BIOMED RESEARCH INTERNATIONAL (2018)
p62-mediated phase separation at the intersection of the ubiquitin-proteasome system and autophagy
Alberto Danieli et al.
JOURNAL OF CELL SCIENCE (2018)
Caloric restriction and cellular senescence
Luigi Fontana et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2018)
Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control
Rahul S. Samant et al.
NATURE (2018)
The proteasome-interacting Ecm29 protein disassembles the 26S proteasome in response to oxidative stress
Xiaorong Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Physical Activity, Sedentary Behavior, and Inflammatory and Hemostatic Markers in Men
Tessa J. Parsons et al.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2017)
Epigenetic Control of Autophagy: Nuclear Events Gain More Attention
Sung Hee Baek et al.
MOLECULAR CELL (2017)
The UPRER: Sensor and Coordinator of Organismal Homeostasis
Ashley E. Frakes et al.
MOLECULAR CELL (2017)
PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR)
Philip Kranz et al.
CELL DEATH & DISEASE (2017)
Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway
Aslihan Ugun-Klusek et al.
CELL DEATH & DISEASE (2017)
The role of the immunoproteasome in interferon-γ-mediated microglial activation
Kasey E. Moritz et al.
SCIENTIFIC REPORTS (2017)
The Role of the Multifunctional BAG3 Protein in Cellular Protein Quality Control and in Disease
Elisabeth Stuerner et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Protein Quality Control by Molecular Chaperones in Neurodegeneration
Aaron Ciechanover et al.
FRONTIERS IN NEUROSCIENCE (2017)
Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease
Filippo Scialo et al.
FRONTIERS IN PHYSIOLOGY (2017)
Redox regulation of proteasome function
Maria Lefaki et al.
REDOX BIOLOGY (2017)
Proteostasis, oxidative stress and aging
Ioanna Korovila et al.
REDOX BIOLOGY (2017)
Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer's disease-like APPPS1 mice
Lisa K. Wagner et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)
Neuroinflammation alters cellular proteostasis by producing endoplasmic reticulum stress, autophagy activation and disrupting ERAD activation
Cristina Pintado et al.
SCIENTIFIC REPORTS (2017)
A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response
Niko Amin-Wetzel et al.
CELL (2017)
The path from mitochondrial ROS to aging runs through the mitochondrial permeability transition pore
Hagai Rottenberg et al.
AGING CELL (2017)
Molecular definitions of autophagy and related processes
Lorenzo Galluzzi et al.
EMBO JOURNAL (2017)
The Logic of the 26S Proteasome
Galen Andrew Collins et al.
CELL (2017)
SQSTM1/p62-mediated autophagy compensates for loss of proteasome polyubiquitin recruiting capacity
Alik Demishtein et al.
AUTOPHAGY (2017)
Inflammaging and Anti-Inflammaging: The Role of Cytokines in Extreme Longevity
Paola Lucia Minciullo et al.
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2016)
Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue
Amiya Kumar Ghosh et al.
AGING-US (2016)
Oxidative Stress by Monoamine Oxidase-A Impairs Transcription Factor EB Activation and Autophagosome Clearance, Leading to Cardiomyocyte Necrosis and Heart Failure
Yohan Santin et al.
ANTIOXIDANTS & REDOX SIGNALING (2016)
Autophagy in sepsis: Degradation into exhaustion?
Jeffery Ho et al.
AUTOPHAGY (2016)
p62 links the autophagy pathway and the ubiqutin-proteasome system upon ubiquitinated protein degradation
Wei Jing Liu et al.
CELLULAR & MOLECULAR BIOLOGY LETTERS (2016)
The fine-tuning of proteolytic pathways in Alzheimer's disease
Valentina Cecarini et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Aging is associated with hypermethylation of autophagy genes in macrophages
Hany Khalil et al.
EPIGENETICS (2016)
Interactions between Autophagy and Inhibitory Cytokines
Tian-tian Wu et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2016)
KIAA0368-deficiency affects disassembly of 26S proteasome under oxidative stress condition
Kousuke Haratake et al.
JOURNAL OF BIOCHEMISTRY (2016)
Degradation of oxidized proteins by the proteasome: Distinguishing between the 20S, 26S, and immunoproteasome proteolytic pathways
Rachel Raynes et al.
MOLECULAR ASPECTS OF MEDICINE (2016)
The Aging Epigenome
Lauren N. Booth et al.
MOLECULAR CELL (2016)
AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy
Hi-Jai R. Shin et al.
NATURE (2016)
Breaking BAG: The Co-Chaperone BAG3 in Health and Disease
Christian Behl
TRENDS IN PHARMACOLOGICAL SCIENCES (2016)
Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts
Christiane Ott et al.
REDOX BIOLOGY (2016)
Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging
Jaime L. Schneider et al.
AGING CELL (2015)
The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells
Yan-Ning Rui et al.
AUTOPHAGY (2015)
Transcriptional and epigenetic regulation of autophagy in aging
Louis R. Lapierre et al.
AUTOPHAGY (2015)
Spliced XBP1 promotes macrophage survival and autophagy by interacting with Beclin-1
Ping-Ge Tian et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Some hormone, cytokine and chemokine levels that change across lifespan vary by cognitive status in male Fischer 344 rats
Rachel B. Scheinert et al.
BRAIN BEHAVIOR AND IMMUNITY (2015)
Participation of proteasome-ubiquitin protein degradation in autophagy and the activation of AMP-activated protein kinase
Shaoning Jiang et al.
CELLULAR SIGNALLING (2015)
p62/SQSTM1 functions as a signaling hub and an autophagy adaptor
Yoshinori Katsuragi et al.
FEBS JOURNAL (2015)
Membrane dynamics in autophagosome biogenesis
Sven R. Carlsson et al.
JOURNAL OF CELL SCIENCE (2015)
Heat shock protein responses to aging and proteotoxicity in the olfactory bulb
Tyler S. Crum et al.
JOURNAL OF NEUROCHEMISTRY (2015)
IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation
Shengyi Sun et al.
NATURE CELL BIOLOGY (2015)
Age-related dysfunctions of the autophagy lysosomal pathway in hippocampal pyramidal neurons under proteasome stress
Elena Gavilan et al.
NEUROBIOLOGY OF AGING (2015)
The loss of glucose-regulated protein 78 (GRP78) during normal aging or from siRNA knockdown augments human alpha-synuclein (α-syn) toxicity to rat nigral neurons
Maxim Salganik et al.
NEUROBIOLOGY OF AGING (2015)
NEUROINFLAMMATION IN THE NORMAL AGING HIPPOCAMPUS
R. M. Barrientos et al.
NEUROSCIENCE (2015)
Dysfunction in protein clearance by the proteasome: impact on autoinflammatory diseases
Anja Brehm et al.
SEMINARS IN IMMUNOPATHOLOGY (2015)
Breast cancer cell line MCF7 escapes from G1/S arrest induced by proteasome inhibition through a GSK-3β dependent mechanism
Elena Gavilan et al.
SCIENTIFIC REPORTS (2015)
Bortezomib induces protective autophagy through AMP-activated protein kinase activation in cultured pancreatic and colorectal cancer cells
Han Min et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2014)
Fasting: Molecular Mechanisms and Clinical Applications
Valter D. Longo et al.
CELL METABOLISM (2014)
Chaperone-mediated autophagy: roles in disease and aging
Ana Maria Cuervo et al.
CELL RESEARCH (2014)
Proteasome Dysfunction Activates Autophagy and the Keap1-Nrf2 Pathway
Shun Kageyama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Endoplasmic Reticulum Stress-Activated Transcription Factor ATF6α Requires the Disulfide Isomerase PDIA5 To Modulate Chemoresistance
Arisa Higa et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy
Vladimir Rogov et al.
MOLECULAR CELL (2014)
Protein Disulfide Isomerase A6 Controls the Decay of IRE1α Signaling via Disulfide-Dependent Association
Davide Eletto et al.
MOLECULAR CELL (2014)
The return of the nucleus: transcriptional and epigenetic control of autophagy
Jens Fullgrabe et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition
Anan Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Reversible 26S Proteasome Disassembly upon Mitochondrial Stress
Nurit Livnat-Levanon et al.
CELL REPORTS (2014)
A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease
Marc Brehme et al.
CELL REPORTS (2014)
Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome
Shona H. Wood et al.
AGE (2013)
Balance between autophagic pathways preserves retinal homeostasis
Natalia Rodriguez-Muela et al.
AGING CELL (2013)
Molecular Chaperone Functions in Protein Folding and Proteostasis
Yujin E. Kim et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82 (2013)
A novel crosstalk between two major protein degradation systems Regulation of proteasomal activity by autophagy
Xiao J. Wang et al.
AUTOPHAGY (2013)
Forming disulfides in the endoplasmic reticulum
Ojore B. V. Oka et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Orchestration of secretory protein folding by ER chaperones
Tali Gidalevitz et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Selective Autophagy: Talking with the UPS
Caroline Park et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2013)
The REGγ Proteasome Regulates Hepatic Lipid Metabolism through Inhibition of Autophagy
Shuxian Dong et al.
CELL METABOLISM (2013)
Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells
Denis Selimovic et al.
CELLULAR SIGNALLING (2013)
Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats
Li Luo et al.
EXPERIMENTAL GERONTOLOGY (2013)
Autophagic response to exercise training in skeletal muscle with age
Yong An Kim et al.
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2013)
Epigenetic Regulation of Autophagy by the Methyltransferase G9a
Amaia Artal-Martinez de Narvajas et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy
Jens Fullgrabe et al.
NATURE (2013)
Review: Microglia of the aged brain: primed to be activated and resistant to regulation
D. M. Norden et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2013)
Knockdown of PSMB7 Induces Autophagy in Cardiomyocyte Cultures: Possible Role in Endoplasmic Reticulum Stress
Victoria O. Kyrychenko et al.
PATHOBIOLOGY (2013)
Poly-Ub-Substrate-Degradative Activity of 26S Proteasome Is Not Impaired in the Aging Rat Brain
Carolin Giannini et al.
PLOS ONE (2013)
Protein Folding in the Endoplasmic Reticulum
Ineke Braakman et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Redox Control of 20S Proteasome Gating
Gustavo M. Silva et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Mutations in proteasome subunit ß type 8 cause chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature with evidence of genetic and phenotypic heterogeneity
Yin Liu et al.
ARTHRITIS AND RHEUMATISM (2012)
Proteasome inhibition-induced p38 MAPK/ERK signaling regulates autophagy and apoptosis through the dual phosphorylation of glycogen synthase kinase 3β
Cheol-Hee Choi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
Jisun Lee et al.
BIOCHEMICAL JOURNAL (2012)
Transient Aggregation of Ubiquitinated Proteins Is a Cytosolic Unfolded Protein Response to Inflammation and Endoplasmic Reticulum Stress
Xian-De Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Age-related differences in the dynamics of hippocampal proteasome recovery
M. Paz Gavilan et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus
Cristina Pintado et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of elF2B
Connie W. Woo et al.
NATURE CELL BIOLOGY (2012)
Chaperones in autophagy
Susmita Kaushik et al.
PHARMACOLOGICAL RESEARCH (2012)
Inhibitory effect of dietary lipids on chaperone-mediated autophagy
Jose Antonio Rodriguez-Navarro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts
Alison M. Connor et al.
ARTHRITIS RESEARCH & THERAPY (2012)
Disulfide Bond Formation in the Mammalian Endoplasmic Reticulum
Neil J. Bulleid
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Microautophagy in mammalian cells Revisiting a 40-year-old conundrum
Dalibor Mijaljica et al.
AUTOPHAGY (2011)
Lipofuscin inhibits the proteasome by binding to surface motifs
Annika Hoehn et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress
Tilman Grune et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
TNF-α Induces Macroautophagy and Regulates MHC Class II Expression in Human Skeletal Muscle Cells
Christian W. Keller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Dynamics of the Degradation of Ubiquitinated Proteins by Proteasomes and Autophagy ASSOCIATION WITH SEQUESTOSOME 1/p62
Natura Myeku et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans
Akiko Kitamura et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Molecular chaperones in protein folding and proteostasis
F. Ulrich Hartl et al.
NATURE (2011)
Proteasome assembly defect due to a proteasome subunit beta type 8 (PSMB8) mutation causes the autoinflammatory disorder, Nakajo-Nishimura syndrome
Kazuhiko Arima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
Peter Walter et al.
SCIENCE (2011)
The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease
Michael Gleeson et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Inhibition of autophagy in the heart induces age-related cardiomyopathy
Manabu Taneike et al.
AUTOPHAGY (2010)
The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes
Andrew M. Pickering et al.
BIOCHEMICAL JOURNAL (2010)
Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress
Ulrike Seifert et al.
CELL (2010)
Immunoproteasomes are essential for survival and expansion of T cells in virus-infected mice
Jacqueline Moebius et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise
Stephanie Eva Wohlgemuth et al.
EXPERIMENTAL GERONTOLOGY (2010)
Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems
Viktor I. Korolchuk et al.
FEBS LETTERS (2010)
Ubiquitylation of an ERAD Substrate Occurs on Multiple Types of Amino Acids
Yuichiro Shimizu et al.
MOLECULAR CELL (2010)
Autophagy and the Integrated Stress Response
Guido Kroemer et al.
MOLECULAR CELL (2010)
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
Fabio Martinon et al.
NATURE IMMUNOLOGY (2010)
Ageing enhances α-synuclein, ubiquitin and endoplasmic reticular stress protein expression in the nigral neurons of Asian Indians
Phalguni Anand Alladi et al.
NEUROCHEMISTRY INTERNATIONAL (2010)
Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells
K. Zhu et al.
ONCOGENE (2010)
Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease
Marta M. Lipinski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Extending Healthy Life Span-From Yeast to Humans
Luigi Fontana et al.
SCIENCE (2010)
Regulation of the 26S Proteasome Complex During Oxidative Stress
Xiaorong Wang et al.
SCIENCE SIGNALING (2010)
Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition
Maria Paz Gavilan et al.
AGING CELL (2009)
Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome
Daniel Finley
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Regulation Mechanisms and Signaling Pathways of Autophagy
Congcong He et al.
ANNUAL REVIEW OF GENETICS (2009)
Regulation and Function of NF-kappa B Transcription Factors in the Immune System
Sivakumar Vallabhapurapu et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
The emerging complexity of protein ubiquitination
David Komander
BIOCHEMICAL SOCIETY TRANSACTIONS (2009)
Guidelines for the nomenclature of the human heat shock proteins
Harm H. Kampinga et al.
CELL STRESS & CHAPERONES (2009)
Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
Martin Gamerdinger et al.
EMBO JOURNAL (2009)
S-Glutathionylation of the Rpn2 Regulatory Subunit Inhibits 26 S Proteasomal Function
Jaroslaw W. Zmijewski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Age-related increase in the immunoproteasome content in rat hippocampus: molecular and functional aspects
M. Paz Gavilan et al.
JOURNAL OF NEUROCHEMISTRY (2009)
ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology
Antero Salminen et al.
JOURNAL OF NEUROINFLAMMATION (2009)
Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates
Viktor I. Korolchuk et al.
MOLECULAR CELL (2009)
A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis
Tony Muchamuel et al.
NATURE MEDICINE (2009)
The proteasome: Overview of structure and functions
Keiji Tanaka
PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2009)
Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome
Wen-Xing Ding et al.
AUTOPHAGY (2008)
Decreased enzyme activities of chaperones PD1 and BiP in aged mouse livers
Jonathan E. Nuss et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Wild type α-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
Tereza Vogiatzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The ubiquitin-proteasome system in Alzheimer's disease
Salvatore Oddo
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
Aging impairs the unfolded protein response to sleep deprivation and leads to proapoptotic signaling
Nirinjini Naidoo et al.
JOURNAL OF NEUROSCIENCE (2008)
Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy
Susmita Kaushik et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Autophagy fights disease through cellular self-digestion
Noboru Mizushima et al.
NATURE (2008)
Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function
Cong Zhang et al.
NATURE MEDICINE (2008)
Aβ inhibits the proteasome and enhances amyloid and tau accumulation
Bertrand P. Tseng et al.
NEUROBIOLOGY OF AGING (2008)
The proteasome immunosubunit multicatalytic endopeptidase complex-like 1 is a T-cell-intrinsic factor influencing homeostatic expansion
Dietmar M. W. Zaiss et al.
INFECTION AND IMMUNITY (2008)
Molecular and cellular characterization of the age-related neuroinflammatory processes occurring in normal rat hippocampus:: potential relation with the loss of somatostatin GABAergic neurons
M. Paz Gavilan et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Overexpression of hUMP1/POMP proteasome accessory protein enhances proteasome-mediated antioxidant defence
Niki Chondrogianni et al.
EXPERIMENTAL GERONTOLOGY (2007)
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
Wen-Xing Ding et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Reduced eIF2α phosphorylation and increased proapoptotic proteins in aging
Syed G. Hussain et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II)
Eriko Fujita et al.
HUMAN MOLECULAR GENETICS (2007)
Altered dynamics of the lysosomal receptor for chaperone-mediated autophagy with age
Roberta Kiffin et al.
JOURNAL OF CELL SCIENCE (2007)
ROS, mitochondria and the regulation of autophagy
Ruth Scherz-Shouval et al.
TRENDS IN CELL BIOLOGY (2007)
Lysosome membrane lipid microdomains: novel regulators of chaperone-mediated autophagy
Susmita Kaushik et al.
EMBO JOURNAL (2006)
Cellular environment facilitates protein accumulation in aged rat hippocampus
M. Paz Gavilan et al.
NEUROBIOLOGY OF AGING (2006)
Loss of autophagy in the central nervous system causes neurodegeneration in mice
Masaaki Komatsu et al.
NATURE (2006)
The effect of aging on the chaperone concentrations in the hepatic, endoplasmic reticulum of male rats: The possible role of protein misfolding due to the loss of chaperones in the decline in physiological function seen with age
Richard R. Erickson et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2006)
Consequences of the selective blockage of chaperone-mediated autophagy
AC Massey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-κB activation and down-regulation of TRAF2 expression
P Hu et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Microglia in the aging brain
Jessica R. Conde et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
Destructive cleavage of antigenic peptides either by the immunoproteasome or by the standard proteasome results in differential antigen presentation
J Chapiro et al.
JOURNAL OF IMMUNOLOGY (2006)
Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains
M Mishto et al.
NEUROBIOLOGY OF AGING (2006)
Oxidative modification of proteasome: Identification of an oxidation-sensitive subunit in 26 S proteasome
T Ishii et al.
BIOCHEMISTRY (2005)
Interferon-γ, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing
B Strehl et al.
IMMUNOLOGICAL REVIEWS (2005)
Novel insights into the mechanism of chaperone-assisted protein disaggregation
J Weibezahn et al.
BIOLOGICAL CHEMISTRY (2005)
Protein degradation and aging
M Martinez-Vicente et al.
EXPERIMENTAL GERONTOLOGY (2005)
The apoptosis/autophagy paradox:: autophagic vacuolization before apoptotic death
RA González-Polo et al.
JOURNAL OF CELL SCIENCE (2005)
Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase
K Cadwell et al.
SCIENCE (2005)
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
M Komatsu et al.
JOURNAL OF CELL BIOLOGY (2005)
Altered proteasome structure, function, and oxidation in aged muscle
DA Ferrington et al.
FASEB JOURNAL (2005)
Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors
M Rechsteiner et al.
TRENDS IN CELL BIOLOGY (2005)
Proteasomes and their kin: Proteases in the machine age
CM Pickart et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Characterization of the hsp70 response in lymphoblasts from aged and centenarian subjects and differential effects of in vitro zinc supplementation
R Ambra et al.
EXPERIMENTAL GERONTOLOGY (2004)
Protein folding and quality control in the endoplasmic reticulum
B Kleizen et al.
CURRENT OPINION IN CELL BIOLOGY (2004)
Catalytic site-specific inhibition of the 20S proteasome by 4-hydroxynonenal
DA Ferrington et al.
FEBS LETTERS (2004)
The role of macroautophagy in the ageing process, anti-ageing intervention and age-associated diseases
E Bergamini et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease
T Grune et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Cooperation of molecular chaperones with the ubiquitin/proteasome system
C Esser et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2004)
Disturbed cholesterol traffic but normal proteolytic function in LAMP-1/LAMP-2 double-deficient fibroblasts
EL Eskelinen et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Altered proteasome function and subunit composition in aged muscle
AD Husom et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
Gene regulation and DNA damage in the ageing human brain
T Lu et al.
NATURE (2004)
Activation of chaperone-mediated autophagy during oxidative stress
R Kiffin et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
ER signaling in unfolded protein response
M Kaneko et al.
LIFE SCIENCES (2003)
Central role of the proteasome in senescence and survival of human fibroblasts - Induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation
N Chondrogianni et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Effect of aging and late onset dietary restriction on antioxidant enzymes and proteasome activities, and protein carbonylation of rat and skeletal muscle and tendon
Z Radák et al.
EXPERIMENTAL GERONTOLOGY (2002)
Role of LAMP-2 in lysosome biogenesis and autophagy
EL Eskelinen et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Age-dependent declines in proteasome activity in the heart
AL Bulteau et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2002)
Oxidative stress and protein aggregation during biological aging
TC Squier
EXPERIMENTAL GERONTOLOGY (2001)
Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion
AL Bulteau et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Impairment of the ubiquitin-proteasome system by protein aggregation
NF Bence et al.
SCIENCE (2001)
26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide
P Cascio et al.
EMBO JOURNAL (2001)
Age-related decline in chaperone-mediated autophagy
AM Cuervo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Age-related alterations of proteasome structure and function in aging epidermis
AL Bulteau et al.
EXPERIMENTAL GERONTOLOGY (2000)
Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice
Y Tanaka et al.
NATURE (2000)
Gene-expression profile of the ageing brain in mice
CK Lee et al.
NATURE GENETICS (2000)
Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress
T Reinheckel et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
Increase of oxidatively modified protein is associated with a decrease of proteasome activity and content in aging epidermal cells
I Petropoulos et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2000)
The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome
J Lüders et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Hydrogen peroxide-mediated protein oxidation in young and old human MRC-5 fibroblasts
K Merker et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
Share Paper
