4.6 Article

Conversion of the Sensor Kinase DcuS to the Fumarate Sensitive State by Interaction of the Bifunctional Transporter DctA at the TM2/PASC-Linker Region

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Transmembrane signaling and cytoplasmic signal conversion by dimeric transmembrane helix 2 and a linker domain of the DcuS sensor kinase

Marius Stopp et al.

Summary: The study demonstrates that the transmembrane helix TM2 of the DcuS sensor kinase forms a stable homodimer in both inactive and fumarate-activated states, with a conserved motif crucial for stability and function. TM2 helix extends into the PASP domain and PAS(C) domain, transmitting signals to the kinase domain. Structural rearrangements in a helical linker connecting TM2 with PAS(C) upon fumarate activation suggest piston-type transmembrane signaling.

JOURNAL OF BIOLOGICAL CHEMISTRY (2021)

Article Biochemistry & Molecular Biology

UniProt: a worldwide hub of protein knowledge

Alex Bateman et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Biochemistry & Molecular Biology

DcuA of aerobically grown Escherichia coli serves as a nitrogen shuttle (L-aspartate/fumarate) for nitrogen uptake

Alexander Strecker et al.

MOLECULAR MICROBIOLOGY (2018)

Review Biochemistry & Molecular Biology

Transporters as information processors in bacterial signalling pathways

Hannah Piepenbreier et al.

MOLECULAR MICROBIOLOGY (2017)

Article Biochemical Research Methods

Cryogenic optical localization provides 3D protein structure data with Angstrom resolution

Siegfried Weisenburger et al.

NATURE METHODS (2017)

Article Multidisciplinary Sciences

Sensory domain contraction in histidine kinase CitA triggers transmembrane signaling in the membrane-bound sensor

Michele Salvi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Biochemistry & Molecular Biology

I-TASSER server: new development for protein structure and function predictions

Jianyi Yang et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Multidisciplinary Sciences

Transmembrane signaling in the sensor kinase DcuS of Escherichia coli: A long-range piston-type displacement of transmembrane helix 2

Christian Monzel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemistry & Molecular Biology

Crystal structure of a substrate-free aspartate transporter

Sonja Jensen et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Structural Basis of a Rationally Rewired Protein-Protein Interface Critical to Bacterial Signaling

Anna I. Podgornaia et al.

STRUCTURE (2013)

Article Biochemical Research Methods

Unipro UGENE: a unified bioinformatics toolkit

Konstantin Okonechnikov et al.

BIOINFORMATICS (2012)

Review Microbiology

Bacterial Sensor Kinases: Diversity in the Recognition of Environmental Signals

Tino Krell et al.

ANNUAL REVIEW OF MICROBIOLOGY, VOL 64, 2010 (2010)

Article Biochemical Research Methods

Protein structure homology modeling using SWISS-MODEL workspace

Lorenza Bordoli et al.

NATURE PROTOCOLS (2009)

Article Biochemistry & Molecular Biology

Crystal structure of a functional dimer of the PhoQ sensor domain

Jonah Cheung et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA

Madhumati Sevvana et al.

JOURNAL OF MOLECULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS

Manuel Etzkorn et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)

Review Cell Biology

Membrane-protein topology

Gunnar von Heijne

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

Review Microbiology

Stimulus perception in bacterial signal-transducing histidine kinases

Thorsten Mascher et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2006)

Article Biochemistry & Molecular Biology

Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection

Tomoya Baba et al.

MOLECULAR SYSTEMS BIOLOGY (2006)

Article Biochemistry & Molecular Biology

The nature of the stimulus and of the fumarate binding site of the fumarate sensor DcuS of Escherichia coli

H Kneuper et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

MUSCLE: multiple sequence alignment with high accuracy and high throughput

RC Edgar

NUCLEIC ACIDS RESEARCH (2004)

Article Chemistry, Multidisciplinary

UCSF chimera - A visualization system for exploratory research and analysis

EF Pettersen et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)