4.7 Review

The Pivotal Role of Oxidative Stress in the Pathophysiology of Cardiovascular-Renal Remodeling in Kidney Disease

Related references

Note: Only part of the references are listed.
Article Cardiac & Cardiovascular Systems

Nutrition in adult patients with selected lysosomal storage diseases

Francesca Carubbi et al.

Summary: Lysosomal storage disorders impact lysosome function, leading to accumulation of undigested substances. While advances in care and treatment have improved survival in certain diseases, symptoms persist. Nutritional therapy may be a potential way to improve quality of life, but specific dietary recommendations remain lacking due to insufficient data.

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2021)

Article Cell Biology

Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress

Linmao Lyu et al.

Summary: Scoparone can alleviate Ang II-induced myocardial hypertrophy and fibrosis by inhibiting oxidative stress mediated by RAC1. It also blocks Ang II-induced cardiomyocyte hypertrophy and cardiac fibroblast collagen synthesis.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

Review Cell Biology

Reactive Oxygen Species and Their Involvement in Red Blood Cell Damage in Chronic Kidney Disease

Krzysztof Gwozdzinski et al.

Summary: Reactive oxygen species are key signaling molecules in cells, but can also lead to oxidative stress if not balanced by antioxidants. Red blood cells play a crucial role in maintaining redox balance in the blood, with hemoglobin being a major player in oxidative stress. Antioxidants like SOD, CAT, and GPx are essential for counteracting oxidative damage, but an imbalance in redox can lead to oxidative stress and disease progression.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)

Article Toxicology

Structural component changes of erythrocytes caused by oxidative stress generated by indoxyl sulfate

Anna Pieniazek et al.

Summary: The findings suggest that IS induces oxidative damage to erythrocyte components, which may affect the functional properties of erythrocytes in CKD patients.

TOXICOLOGY IN VITRO (2021)

Review Urology & Nephrology

Uraemic solutes as therapeutic targets in CKD-associated cardiovascular disease

Jonathan D. Ravid et al.

Summary: Chronic kidney disease is characterized by the retention of uraemic toxins that damage organs, including the cardiovascular system. Targeting uraemic toxins through pharmacological and non-pharmacological approaches can help lower the risk of cardiovascular disease.

NATURE REVIEWS NEPHROLOGY (2021)

Article Multidisciplinary Sciences

Plasminogen Activator Inhibitor-1 in poorly controlled vs well controlled Type-2 Diabetes Mellitus patients: A case-control study in a district hospital in Ghana

Charles Nkansah et al.

Summary: Elevated PAI-1 antigen/activity levels were observed in poorly controlled Ghanaian T2DM patients, with a significant positive correlation between HbA1c and PAI-1 enzymes. Good glycemic control is essential in managing T2DM and regulating plasma PAI-1 levels to reduce the risk of cardiovascular diseases.

PLOS ONE (2021)

Article Engineering, Biomedical

Oxidative stress, inflammation, and peritoneal dialysis: A molecular biology approach

Georgie Innico et al.

Summary: The study found that oxidative stress and inflammation increase in peritoneal dialysis patients, despite certain specific hemodialysis procedures may be beneficial. To improve the oxidative stress state in peritoneal dialysis patients, a multitarget approach is necessary, including adjustments in dialysis solution composition, strict glycemic control, optimal volume management, and the administration of antioxidants.

ARTIFICIAL ORGANS (2021)

Review Medicine, General & Internal

ROCK (RhoA/Rho Kinase) in Cardiovascular-Renal Pathophysiology: A Review of New Advancements

Teresa M. Seccia et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Review Cell Biology

NF-κB and tPA Signaling in Kidney and Other Diseases

Samantha White et al.

CELLS (2020)

Article Cardiac & Cardiovascular Systems

Short-Term Systolic Blood Pressure Variability and Kidney Disease Progression in Patients With Chronic Kidney Disease: Results From C-STRIDE

Qin Wang et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2020)

Review Endocrinology & Metabolism

New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity

Masato Furuhashi

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2020)

Review Urology & Nephrology

Is oxidative stress an issue in peritoneal dialysis?

Stefanos Roumeliotis et al.

SEMINARS IN DIALYSIS (2019)

Review Cell Biology

Sodium-glucose cotransporter inhibitors and oxidative stress: An update

Habib Yaribeygi et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Review Biochemistry & Molecular Biology

Effects of Glucagon-Like Peptide-1 on Oxidative Stress and Nrf2 Signaling

Yoon Sin Oh et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Cardiac & Cardiovascular Systems

Expression of Rho Kinase and Its Mechanism in the Left Atrial Appendage in Patients with Atrial Fibrillation

Chen Yongqing et al.

HEART SURGERY FORUM (2018)

Review Physiology

ANGIOTENSIN II SIGNAL TRANSDUCTION: AN UPDATE ON MECHANISMS OF PHYSIOLOGY AND PATHOPHYSIOLOGY

Steven J. Forrester et al.

PHYSIOLOGICAL REVIEWS (2018)

Review Medicine, Research & Experimental

Oxidative stress - chronic kidney disease - cardiovascular disease: A vicious circle

Verdiana Ravarotto et al.

LIFE SCIENCES (2018)

Review Peripheral Vascular Disease

Hypertensive nephropathy. Moving from classic to emerging pathogenetic mechanisms

Teresa M. Seccia et al.

JOURNAL OF HYPERTENSION (2017)

Review Cell Biology

Role of ROS and RNS Sources in Physiological and Pathological Conditions

Sergio Di Meo et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

Review Cardiac & Cardiovascular Systems

Oxidative Stress and Human Hypertension: Vascular Mechanisms, Biomarkers, and Novel Therapies

Augusto C. Montezano et al.

CANADIAN JOURNAL OF CARDIOLOGY (2015)

Article Biochemistry & Molecular Biology

Oxidative stress and autophagy: Crucial modulators of kidney injury

Angara Sureshbabu et al.

REDOX BIOLOGY (2015)

Review Peripheral Vascular Disease

Angiotensin II and Cardiovascular-Renal Remodelling in Hypertension: Insights from a Human Model Opposite to Hypertension

Verdiana Ravarotto et al.

HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION (2015)

Article Pharmacology & Pharmacy

Blood pressure measurements, blood pressure variability and endothelial function in renal transplant recipients

Nihal Ozkayar et al.

CLINICAL AND EXPERIMENTAL HYPERTENSION (2014)

Article Peripheral Vascular Disease

Angiotensin II and Vascular Injury

Augusto C. Montezano et al.

CURRENT HYPERTENSION REPORTS (2014)

Article Peripheral Vascular Disease

Increased level of p63RhoGEF and RhoA/Rho kinase activity in hypertensive patients

Lorenzo A. Calo et al.

JOURNAL OF HYPERTENSION (2014)

Review Endocrinology & Metabolism

Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells

Young-Sun Lee et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2014)

Review Cell Biology

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

Antonio Ayala et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)

Review Pediatrics

Trace elements in dialysis

Guido Filler et al.

PEDIATRIC NEPHROLOGY (2014)

Article Cell Biology

Beneficial effect of prolonged heme oxygenase 1 activation in a rat model of chronic heart failure

Massimo Collino et al.

DISEASE MODELS & MECHANISMS (2013)

Review Cell Biology

Oxidative Stress and Nucleic Acid Oxidation in Patients with Chronic Kidney Disease

Chih-Chien Sung et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)

Review Urology & Nephrology

The Renin-Angiotensin-Aldosterone System in Podocytes

Dirk Oliver Wennmann et al.

SEMINARS IN NEPHROLOGY (2012)

Review Cardiac & Cardiovascular Systems

Rho-kinase: important new therapeutic target in cardiovascular diseases

Kimio Satoh et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)

Review Biochemistry & Molecular Biology

Heme Oxygenase in the Regulation of Vascular Biology: From Molecular Mechanisms to Therapeutic Opportunities

Young-Myeong Kim et al.

ANTIOXIDANTS & REDOX SIGNALING (2011)

Article Peripheral Vascular Disease

Cell Signaling of Angiotensin II on Vascular Tone: Novel Mechanisms

Aurelie Nguyen Dinh Cat et al.

CURRENT HYPERTENSION REPORTS (2011)

Review Biochemistry & Molecular Biology

Cross talk between mitochondria and NADPH oxidases

Sergey Dikalov

FREE RADICAL BIOLOGY AND MEDICINE (2011)

Article Biochemistry & Molecular Biology

The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure

Christophe Guilluy et al.

NATURE MEDICINE (2010)

Review Urology & Nephrology

Red Blood Cell Damage from Extracorporeal Circulation in Hemodialysis

Hans-Dietrich Polaschegg

SEMINARS IN DIALYSIS (2009)

Article Urology & Nephrology

Blood-Membrane Interactions During Dialysis

Zhongping Huang et al.

SEMINARS IN DIALYSIS (2009)

Article Cardiac & Cardiovascular Systems

Why have antioxidants failed in clinical trials?

Steven R. Steinhubl

AMERICAN JOURNAL OF CARDIOLOGY (2008)

Article Cardiac & Cardiovascular Systems

Xanthine oxidase and mitochondria contribute to vascular superoxide anion generation in DOCA-salt hypertensive rats

Emilie C. Viel et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2008)

Review Biochemistry & Molecular Biology

Redox control of renal function and hypertension

Ravi Nistala et al.

ANTIOXIDANTS & REDOX SIGNALING (2008)

Review Hematology

Final common molecular pathways of aging and cardiovascular disease - Role of the p66(Shc) protein

Francesco Cosentino et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2008)

Article Transplantation

Effect of haemodiafiltration with online regeneration of ultrafiltrate on oxidative stress in dialysis patients

Lorenzo A. Calo et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2007)

Review Medicine, General & Internal

Mortality in randomized trials of antioxidant supplements for primary and secondary prevention - Systematic review and meta-analysis

Goran Bjelakovic et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)

Review Peripheral Vascular Disease

RhoA/Rho-kinase pathway:: much more than just a modulation of vascular tone.: Evidence from studies in humans

Lorenzo A. Calo et al.

JOURNAL OF HYPERTENSION (2007)

Review Urology & Nephrology

Involvement of NADPH oxidases in cardiac remodelling and heart failure

Alexander Sirker et al.

AMERICAN JOURNAL OF NEPHROLOGY (2007)

Review Urology & Nephrology

Plasminogen activator inhibitor-1 in chronic kidney disease: Evidence and mechanisms of action

Allison A. Eddy et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)

Review Cardiac & Cardiovascular Systems

Rho kinases in cardiovascular physiology and pathophysiology

G Loirand et al.

CIRCULATION RESEARCH (2006)

Review Biochemistry & Molecular Biology

Regulation of the phagocyte NADPH oxidase by Rac GTPase

Gary M. Bokoch et al.

ANTIOXIDANTS & REDOX SIGNALING (2006)

Article Peripheral Vascular Disease

Rho kinase and PAI-1 in Bartter/Gitelman syndromes.: Relationship to angiotensin II signaling

E Pagnin et al.

JOURNAL OF HYPERTENSION (2004)

Review Physiology

Vascular NAD(P)H oxidases:: specific features, expression, and regulation

B Lassègue et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2003)

Article Transplantation

Oxidative stress in end-stage renal disease: an emerging threat to patient outcome

F Locatelli et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2003)

Article Cardiac & Cardiovascular Systems

Oxidative stress in kidney transplant patients with calcineurin inhibitor-induced hypertension:: Effect of ramipril

LA Calò et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2002)