Related references
Note: Only part of the references are listed.Transmission of cerebral amyloid pathology by peripheral administration of misfolded Aβ aggregates
Rodrigo Morales et al.
MOLECULAR PSYCHIATRY (2021)
Amyloid pathology arrangements in Alzheimer's disease brains modulate in vivo seeding capability
Claudia Duran-Aniotz et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2021)
Insulin Resistance and Diabetes Mellitus in Alzheimer's Disease
Jesus Burillo et al.
CELLS (2021)
mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder
M. Perluigi et al.
FREE RADICAL BIOLOGY AND MEDICINE (2021)
Clock-Modulating Activities of the Anti-Arrhythmic Drug Moricizine
Chorong Han et al.
CLOCKS & SLEEP (2021)
Genetics of the human circadian clock and sleep homeostat
Liza H. Ashbrook et al.
NEUROPSYCHOPHARMACOLOGY (2020)
Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease
Jiyeon Lee et al.
AGING CELL (2020)
Systems Level Understanding of Circadian Integration with Cell Physiology
Andrew R. Morris et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis
Volodymyr Petrenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer's Disease
Md. Sahab Uddin et al.
MOLECULES (2020)
Cardiolipin Synthesis in Skeletal Muscle Is Rhythmic and Modifiable by Age and Diet
Kazunari Nohara et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)
Circadian regulation of chemotherapy-induced peripheral neuropathic pain and the underlying transcriptomic landscape
Hee Kee Kim et al.
SCIENTIFIC REPORTS (2020)
The GSK-3 beta-FBXL21 Axis Contributes to Circadian TCAP Degradation and Skeletal Muscle Function
Marvin Wirianto et al.
CELL REPORTS (2020)
Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior
Marion Soto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans
Jerrah K. Holth et al.
SCIENCE (2019)
Sex differences in Alzheimer's disease: Understanding the molecular impact
Carlos A. Toro et al.
BRAIN RESEARCH (2019)
Mitochondrial (Dys) function and Insulin Resistance: From Pathophysiological Molecular Mechanisms to the Impact of Diet
Domenico Sergi et al.
FRONTIERS IN PHYSIOLOGY (2019)
Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer's Disease and Parkinson's Disease
Akira Nakajima et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer's disease
Deborah A. Roby et al.
PLOS ONE (2019)
Coordinate Regulation of Cholesterol and Bile Acid Metabolism by the Clock Modifier Nobiletin in Metabolically Challenged Old Mice
Kazunari Nohara et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge
Kazunari Nohara et al.
NATURE COMMUNICATIONS (2019)
Inhibition of casein kinase 1δ/ε improves cognitive-affective behavior and reduces amyloid load in the APP-PS1 mouse model of Alzheimer's disease
S. Sundaram et al.
SCIENTIFIC REPORTS (2019)
Calorie restriction reprograms diurnal rhythms in protein translation to regulate metabolism
Kuldeep Makwana et al.
FASEB JOURNAL (2019)
Crosstalk between NFκB-dependent astrocytic CXCL1 and neuron CXCR2 plays a role in descending pain facilitation
Huadong Ni et al.
JOURNAL OF NEUROINFLAMMATION (2019)
Timing Matters: Circadian Effects on Energy Homeostasis and Alzheimer's Disease
Aline Loehfelm et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2019)
Housefly (Musca domestica) larvae powder, preventing oxidative stress injury via regulation of UCP4 and CyclinD1 and modulation of JNK and P38 signaling in APP/PS1 mice
Yinru He et al.
FOOD & FUNCTION (2019)
Development and Therapeutic Potential of Small-Molecule Modulators of Circadian Systems
Zheng Chen et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 58 (2018)
Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States
Mark P. Mattson et al.
CELL METABOLISM (2018)
Regulation of amyloid-β dynamics and pathology by the circadian clock
Geraldine J. Kress et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
Palmitate-induced C/EBP homologous protein activation leads to NF-κB-mediated increase in BACE1 activity and amyloid beta genesis
Gurdeep Marwarha et al.
JOURNAL OF NEUROCHEMISTRY (2018)
Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums
Steven E. Arnold et al.
NATURE REVIEWS NEUROLOGY (2018)
Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases
Gabriele Sulli et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Transcriptional architecture of the mammalian circadian clock
Joseph S. Takahashi
NATURE REVIEWS GENETICS (2017)
Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer's disease
Jennifer M. Walker et al.
NEUROBIOLOGY OF DISEASE (2017)
YXQN Reduces Alzheimer's Disease-Like Pathology and Cognitive Decline in APPswePS1dE9 Transgenic Mice
Xiaowan Wang et al.
FRONTIERS IN AGING NEUROSCIENCE (2017)
Mice under Caloric Restriction Self-Impose a Temporal Restriction of Food Intake as Revealed by an Automated Feeder System
Victoria A. Acosta-Rodriguez et al.
CELL METABOLISM (2017)
Intranasal insulin alleviates cognitive deficits and amyloid pathology in young adult APPswe/PS1dE9 mice
Yan-Fang Mao et al.
AGING CELL (2016)
Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis
Erin E. Mulvihill et al.
ANNUAL REVIEW OF NUTRITION, VOL 36 (2016)
The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome
Baokun He et al.
CELL METABOLISM (2016)
The Multifunctional Effects of Nobiletin and Its Metabolites In Vivo and In Vitro
Hao Huang et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2016)
Neurodegenerative Diseases: Might Citrus Flavonoids Play a Protective Role?
Santa Cirmi et al.
MOLECULES (2016)
Impaired thermoregulation and beneficial effects of thermoneutrality in the 3xTg-AD model of Alzheimer's disease
Milene Vandal et al.
NEUROBIOLOGY OF AGING (2016)
Circadian time signatures of fitness and disease
Joseph Bass et al.
SCIENCE (2016)
Mechanisms linking circadian clocks, sleep, and neurodegeneration
Erik S. Musiek et al.
SCIENCE (2016)
Circadian Rhythms, Sleep, and Disorders of Aging
Joanna Mattis et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2016)
Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer's disease-risk genes
Zhixiong Ma et al.
SCIENTIFIC REPORTS (2016)
Ammonia-lowering activities and carbamoyl phosphate synthetase 1 (Cps1) induction mechanism of a natural flavonoid
Kazunari Nohara et al.
NUTRITION & METABOLISM (2015)
Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease
Jee Hoon Roh et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
REV-ERB and ROR nuclear receptors as drug targets
Douglas J. Kojetin et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
'The clocks that time us'-circadian rhythms in neurodegenerative disorders
Aleksandar Videnovic et al.
NATURE REVIEWS NEUROLOGY (2014)
The Circadian System in Alzheimer's Disease: Disturbances, Mechanisms, and Opportunities
Andrew N. Coogan et al.
BIOLOGICAL PSYCHIATRY (2013)
Nobiletin-rich Citrus reticulata peels, a kampo medicine for Alzheimer's disease: A case series
Takashi Seki et al.
GERIATRICS & GERONTOLOGY INTERNATIONAL (2013)
Sleep Drives Metabolite Clearance from the Adult Brain
Lulu Xie et al.
SCIENCE (2013)
Modification of the Relationship of the Apolipoprotein E ε4 Allele to the Risk of Alzheimer Disease and Neurofibrillary Tangle Density by Sleep
Andrew S. P. Lim et al.
JAMA NEUROLOGY (2013)
Central and Peripheral Circadian Clocks in Mammals
Jennifer A. Mohawk et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 35 (2012)
Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet
Megumi Hatori et al.
CELL METABOLISM (2012)
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
Konrad Talbot et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
The circadian clock and pathology of the ageing brain
Anna A. Kondratova et al.
NATURE REVIEWS NEUROSCIENCE (2012)
Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women
Gregory J. Tranah et al.
ANNALS OF NEUROLOGY (2011)
Circadian Clock Gene Expression in Brain Regions of Alzheimer's Disease Patients and Control Subjects
Nicolas Cermakian et al.
JOURNAL OF BIOLOGICAL RHYTHMS (2011)
Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Aβ deposition in an Alzheimer mouse model with diabetes
Shuko Takeda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle
Jae-Eun Kang et al.
SCIENCE (2009)
Metabolic syndrome and the role of dietary lifestyles in Alzheimer's disease
Giulio Maria Pasinetti et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Amyloid beta deposition is related to decreased glucose transporter-1 levels and hippocampal atrophy in brains of aged APP/PS1 mice
Carlijn R. Hooijmans et al.
BRAIN RESEARCH (2007)
Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?
Thomas Walle
SEMINARS IN CANCER BIOLOGY (2007)
Intercellular coupling confers robustness against mutations in the SCN circadian clock network
Andrew C. Liu et al.
CELL (2007)
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
Michael T. Lin et al.
NATURE (2006)
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - is this type 3 diabetes?
E Steen et al.
JOURNAL OF ALZHEIMERS DISEASE (2005)
Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease
L Ho et al.
FASEB JOURNAL (2004)
Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo:: evidence for augmentation of a 42-specific γ secretase
JL Jankowsky et al.
HUMAN MOLECULAR GENETICS (2004)
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
KF Petersen et al.
SCIENCE (2003)