Related references
Note: Only part of the references are listed.Receptor-Arrestin Interactions: The GPCR Perspective
Mohammad Seyedabadi et al.
BIOMOLECULES (2021)
Coevolution underlies GPCR-G protein selectivity and functionality
Min Jae Seo et al.
SCIENTIFIC REPORTS (2021)
Rapid Simulation of Unprocessed DEER Decay Data for Protein Fold Prediction
Diego del Alamo et al.
BIOPHYSICAL JOURNAL (2020)
Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor
Carl-Mikael Suomivuori et al.
SCIENCE (2020)
Single-molecule analysis reveals agonist-specific dimer formation of μ-opioid receptors
Jan Moeller et al.
NATURE CHEMICAL BIOLOGY (2020)
Phosphorylation barcode-dependent signal bias of the dopamine D1 receptor
Ali I. Kaya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Synthetic nanobodies as angiotensin receptor blockers
Conor McMahon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Structural insights into differences inGprotein activation by family Aand family BGPCRs
Daniel Hilger et al.
SCIENCE (2020)
Conformational Basis of G Protein-Coupled Receptor Signaling Versatility
Laura M. Wingler et al.
TRENDS IN CELL BIOLOGY (2020)
Probing the Y2Receptor on Transmembrane, Intra- and Extra-Cellular Sites for EPR Measurements
Jeannette M. Laugwitz et al.
MOLECULES (2020)
How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling
Naomi R. Latorraca et al.
CELL (2020)
Viewing rare conformations of the β2 adrenergic receptor with pressure-resolved DEER spectroscopy
Michael T. Lerch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Assembly of a GPCR-G Protein Complex
Yang Du et al.
CELL (2019)
Allostery in G protein-coupled receptors investigated by molecular dynamics simulations
Joao Marcelo Lamim Ribeiro et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2019)
Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement
Eugene O. Grushevskyi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Local membrane charge regulates β2 adrenergic receptor coupling to Gi3
M. J. Strohman et al.
NATURE COMMUNICATIONS (2019)
Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit
Ching-Ju Tsai et al.
ELIFE (2019)
Cryo-EM structure of the native rhodopsin dimer in nanodiscs
Dorothy Yanling Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations
Laura M. Wingler et al.
CELL (2019)
MMM: A toolbox for integrative structure modeling
Gunnar Jeschke
PROTEIN SCIENCE (2018)
A Bioresistant Nitroxide Spin Label for In-Cell EPR Spectroscopy: In Vitro and In Oocytes Protein Structural Dynamics Studies
Ganesan Karthikeyan et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Lipids Alter Rhodopsin Function via Ligand-like and Solvent-like Interactions
Leslie A. Salas-Estrada et al.
BIOPHYSICAL JOURNAL (2018)
The arrestin-1 finger loop interacts with two distinct conformations of active rhodopsin
Matthias Elgeti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Biased signalling: from simple switches to allosteric microprocessors
Jeffrey S. Smith et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Structure and dynamics of GPCR signaling complexes
Daniel Hilger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
G(i)- and G(s)-coupled GPCRs show different modes of G-protein binding
Ned Van Eps et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Dynamic tuneable G protein-coupled receptor monomer-dimer populations
Patricia M. Dijkman et al.
NATURE COMMUNICATIONS (2018)
Structure and dynamics of GPCR signaling complexes
Daniel Hilger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Measuring ligand efficacy at the muopioid receptor using a conformational biosensor
Kathryn E. Livingston et al.
ELIFE (2018)
The Molecular Basis of G Protein-Coupled Receptor Activation
William I. Weis et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 87 (2018)
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein
Yanyong Kang et al.
NATURE (2018)
GPCR Dynamics: Structures in Motion
Naomi R. Latorraca et al.
CHEMICAL REVIEWS (2017)
Phosphorylation of G Protein-Coupled Receptors: From the Barcode Hypothesis to the Flute Model
Zhao Yang et al.
MOLECULAR PHARMACOLOGY (2017)
Single-molecule analysis of ligand efficacy in β2AR-G-protein activation
G. Glenn Gregorio et al.
NATURE (2017)
Conformational equilibria of light-activated rhodopsin in nanodiscs
Ned Van Eps et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Allosteric regulation of G protein-coupled receptor activity by phospholipids
Rosie Dawaliby et al.
NATURE CHEMICAL BIOLOGY (2016)
GPCR-styrene maleic acid lipid particles (GPCR-SMALPs): their nature and potential
Mark Wheatley et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2016)
Toward Precise Interpretation of DEER-Based Distance Distributions: Insights from Structural Characterization of V1 Spin-Labeled Side Chains
Aidin R. Balo et al.
BIOCHEMISTRY (2016)
Ligand-Dependent Modulation of G Protein Conformation Alters Drug Efficacy
Sebastian George Barton Furness et al.
CELL (2016)
Mechanistic insights into GPCR-G protein interactions
Jacob P. Mahoney et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2016)
A triarylmethyl spin label for long-range distance measurement at physiological temperatures using T1 relaxation enhancement
Zhongyu Yang et al.
JOURNAL OF MAGNETIC RESONANCE (2016)
β2-Adrenergic Receptor Conformational Response to Fusion Protein in the Third Intracellular Loop
Matthew T. Eddy et al.
STRUCTURE (2016)
A mechanistic role of Helix 8 in GPCRs: Computational modeling of the dopamine D2 receptor interaction with the GIPC1-PDZ-domain
Ozge Sensoy et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
Room-Temperature Distance Measurements of Immobilized Spin-Labeled Protein by DEER/PELDOR
Virginia Meyer et al.
BIOPHYSICAL JOURNAL (2015)
Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling
Aashish Manglik et al.
CELL (2015)
NMR studies of membrane proteins
Rob Kaptein et al.
JOURNAL OF BIOMOLECULAR NMR (2015)
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Yanyong Kang et al.
NATURE (2015)
Structure-relaxation mechanism for the response of T4 lysozyme cavity mutants to hydrostatic pressure
Michael T. Lerch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Single-Molecule Observation of the Ligand-Induced Population Shift of Rhodopsin, A G-Protein-Coupled Receptor
Ryo Maeda et al.
BIOPHYSICAL JOURNAL (2014)
Divergent Transducer-specific Molecular Efficacies Generate Biased Agonism at a G Protein-coupled Receptor ( GPCR)
Ryan T. Strachan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Position of Transmembrane Helix 6 Determines Receptor G Protein Coupling Specificity
Alexander S. Rose et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Long-Range Distance Measurements in Proteins at Physiological Temperatures Using Saturation Recovery EPR Spectroscopy
Zhongyu Yang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Crystal structure of a common GPCR-binding interface for G protein and arrestin
Michal Szczepek et al.
NATURE COMMUNICATIONS (2014)
G Protein-Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives
Sergi Ferre et al.
PHARMACOLOGICAL REVIEWS (2014)
Cooperative Unfolding of Compact Conformations of the Intrinsically Disordered Protein Osteopontin
Dennis Kurzbach et al.
BIOCHEMISTRY (2013)
Technological advances in site-directed spin labeling of proteins
Wayne L. Hubbell et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2013)
Structure and dynamics of an imidazoline nitroxide side chain with strongly hindered internal motion in proteins
Dora Toledo Warshaviak et al.
JOURNAL OF MAGNETIC RESONANCE (2013)
The Role of Ligands on the Equilibria Between Functional States of a G Protein-Coupled Receptor
Tae Hun Kim et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Effect of intracellular loop 3 on intrinsic dynamics of human β2-adrenergic receptor
Ozer Ozcan et al.
BMC STRUCTURAL BIOLOGY (2013)
Ice breaking in GPCR structural biology
Qiang Zhao et al.
ACTA PHARMACOLOGICA SINICA (2012)
DEER Distance Measurements on Proteins
Gunnar Jeschke
ANNUAL REVIEW OF PHYSICAL CHEMISTRY, VOL 63 (2012)
Spatial arrangement of rhodopsin in retinal rod outer segment membranes studied by spin-labeling and pulsed electron double resonance
Satoshi Yasuda et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Mapping Molecular Flexibility of Proteins with Site-Directed Spin Labeling: A Case Study of Myoglobin
Carlos J. Lopez et al.
BIOCHEMISTRY (2012)
Computer Modeling of Nitroxide Spin Labels on Proteins
Ma'mon M. Hatmal et al.
BIOPOLYMERS (2012)
Role of Detergents in Conformational Exchange of a G Protein-coupled Receptor
Ka Young Chung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
DEER-Stitch: Combining three- and four-pulse DEER measurements for high sensitivity, deadtime free data
J. E. Lovett et al.
JOURNAL OF MAGNETIC RESONANCE (2012)
Structural Transitions of Transmembrane Helix 6 in the Formation of Metarhodopsin I
Markus Eilers et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2012)
Biased Signaling Pathways in β2-Adrenergic Receptor Characterized by 19F-NMR
Jeffrey J. Liu et al.
SCIENCE (2012)
Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors
Eugene Chun et al.
STRUCTURE (2012)
Diversity and modularity of G protein-coupled receptor structures
Vsevolod Katritch et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
A rigid disulfide-linked nitroxide side chain simplifies the quantitative analysis of PRE data
Nicolas L. Fawzi et al.
JOURNAL OF BIOMOLECULAR NMR (2011)
Conserved Tyr2235.58 Plays Different Roles in the Activation and G-Protein Interaction of Rhodopsin
Matthias Elgeti et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
Soren G. F. Rasmussen et al.
NATURE (2011)
Crystal structure of the β2 adrenergic receptor-Gs protein complex
Soren G. F. Rasmussen et al.
NATURE (2011)
Structure and dynamics of a conformationally constrained nitroxide side chain and applications in EPR spectroscopy
Mark R. Fleissner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Activation mechanism of the β2-adrenergic receptor
Ron O. Dror et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Structure and Activation of the Visual Pigment Rhodopsin
Steven O. Smith
ANNUAL REVIEW OF BIOPHYSICS, VOL 39 (2010)
Comparative Sequence and Structural Analyses of G-Protein-Coupled Receptor Crystal Structures and Implications for Molecular Models
Catherine L. Worth et al.
PLOS ONE (2009)
Crystal structure of opsin in its G-protein-interacting conformation
Patrick Scheerer et al.
NATURE (2008)
Two protonation switches control rhodopsin activation in membranes
Mohana Mahalingam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation
Christian Altenbach et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution
Oliver F. Lange et al.
SCIENCE (2008)
Sequence of late molecular events in the activation of rhodopsin
Bernhard Knierim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function
Daniel M. Rosenbaum et al.
SCIENCE (2007)
Structural and dynamical changes in an α-subunit of a heterotrimeric G protein along the activation pathway
Ned Van Eps et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Conformational states and dynamics of rhodopsin in micelles and bilayers
AK Kusnetzow et al.
BIOCHEMISTRY (2006)
Assessing oligomerization of membrane proteins by four-pulse DEER:: pH-dependent dimerization of NhaA Na+/H+ antiporter of E-coli
D Hilger et al.
BIOPHYSICAL JOURNAL (2005)
The study of G-protein coupled receptor oligomerization with computational modeling and bioinformatics
M Filizola et al.
FEBS JOURNAL (2005)
Light-driven activation of β2-adrenergic receptor signaling by a chimeric rhodopsin containing the β2-adrenergic receptor cytoplasmic loops
JM Kim et al.
BIOCHEMISTRY (2005)
G protein-coupled receptors show unusual patterns of intrinsic unfolding
VP Jaakola et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2005)
Electron crystallography reveals the structure of metarhodopsin I
JJ Ruprecht et al.
EMBO JOURNAL (2004)
The G-protein-coupled receptors in the human genome form five main families.: Phylogenetic analysis, paralogon groups, and fingerprints
R Fredriksson et al.
MOLECULAR PHARMACOLOGY (2003)
Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation
O Fritze et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor - Identification of a novel locked-on phenotype and double revertant mutations
C Prioleau et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Estimation of inter-residue distances in spin labeled proteins at physiological temperatures: Experimental strategies and practical limitations
C Altenbach et al.
BIOCHEMISTRY (2001)
Molecular motion of spin labeled side chains in α-helices:: Analysis by variation of side chain structure
L Columbus et al.
BIOCHEMISTRY (2001)
Dead-time free measurement of dipole-dipole interactions between electron spins
M Pannier et al.
JOURNAL OF MAGNETIC RESONANCE (2000)
Share Paper
