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INFLAMMATORY BOWEL DISEASES (2007)
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
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NATURE GENETICS (2007)
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease
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GUT (2007)
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae (Vol 2, pg 119, 2007)
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CELL HOST & MICROBE (2007)
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
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CELLULAR MICROBIOLOGY (2006)
Association of trough serum infliximab to clinical outcome after scheduled maintenance treatment for Crohn's disease
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CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2006)
The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
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CELL (2006)
Metagenomic analysis of the human distal gut microbiome
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SCIENCE (2006)
Heterogeneous expression of human cathelicidin hCAP18/LL-37 in inflammatory bowel diseases
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EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2006)
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
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NATURE (2006)
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GASTROENTEROLOGY (2006)
Genetic basis for increased intestinal permeability in families with Crohn's disease:: role of CARD15 3020insC mutation?
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GUT (2006)
TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
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IMMUNITY (2006)
Increased number of mature dendritic cells in Crohn's disease: evidence for a chemokine mediated retention mechanism
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GUT (2006)
Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach
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GUT (2006)
Reduced Paneth cell α-defensins in ileal Crohn's disease
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Inducing and expanding regulatory T cell populations by foreign antigen
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NATURE IMMUNOLOGY (2005)
Bacterial interactions with cells of the intestinal mucosa: toll-like receptors and NOD2
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GUT (2005)
Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota
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IMMUNOLOGICAL REVIEWS (2005)
Characteristics of intestinal dendritic cells in inflammatory bowel diseases
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GASTROENTEROLOGY (2005)
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SCIENCE (2005)
Peripheral and intestinal regulatory CD4+CD25high T cells in inflammatory bowel disease
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GASTROENTEROLOGY (2005)
NOD2 and Crohn's disease: Loss or gain of function?
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IMMUNITY (2005)
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
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SCIENCE (2005)
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
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JOURNAL OF EXPERIMENTAL MEDICINE (2005)
The pathogenesis of gastrointestinal bacterial overgrowth
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CHEMOTHERAPY (2005)
Infliximab maintenance therapy for fistulizing Crohn's disease
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NEW ENGLAND JOURNAL OF MEDICINE (2004)
Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease
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GASTROENTEROLOGY (2004)
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease
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GASTROENTEROLOGY (2004)
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal α-defensin expression
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GUT (2004)
Antibiotic treatment of small bowel bacterial overgrowth in patients with Crohn's disease
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ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2003)
Porphyria cutanea tarda as a predictor of poor response to interferon alfa therapy in chronic hepatitis C
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SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2003)
Upregulation of interleukin-12 and-17 in active inflammatory bowel disease
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SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2003)
Increased expression of interleukin 17 in inflammatory bowel disease
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GUT (2003)
Differential expression of alpha- and beta-defensins in human peripheral blood
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EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2003)
Bacterial translocation in patients with Crohn's disease undergoing surgery
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DISEASES OF THE COLON & RECTUM (2002)
Decoding the patterns of self and nonself by the innate immune system
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SCIENCE (2002)
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
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NATURE (2001)
Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria
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NATURE IMMUNOLOGY (2001)
A Toll-like receptor recognizes bacterial DNA
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NATURE (2000)
Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk
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GASTROENTEROLOGY (2000)
Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease
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GASTROENTEROLOGY (2000)
Use of short-term culture for identification of Mycobacterium avium subsp paratuberculosis in tissue from Crohn's disease patients
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CLINICAL MICROBIOLOGY AND INFECTION (2000)
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation:: Evidence in Crohn disease and experimental colitis in vivo
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NATURE MEDICINE (2000)
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