4.5 Article

Pu-erh tea extraction alleviates intestinal inflammation in mice with flora disorder by regulating gut microbiota

Journal

FOOD SCIENCE & NUTRITION
Volume 9, Issue 9, Pages 4883-4892

Publisher

WILEY
DOI: 10.1002/fsn3.2437

Keywords

16S rRNA; gut microbiota; intestinal inflammation; Pu-erh tea extract

Funding

  1. China Agriculture Research System-23 [CARS-23]

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Pu-erh tea aqueous extracts have beneficial effects on an intestinal flora disorder mouse model by promoting the growth of intestinal probiotics and inhibiting pathogenic bacteria, which helps in the treatment of enteritis.
Pu-erh tea is very popular in Southwestern China and South Asian countries and is now becoming increasingly popular in Europe due to its well-documented beneficial effects on human health. Pu-erh tea aqueous extracts can maintain intestinal homeostasis. However, the mechanism of its beneficial effects on intestinal flora disorder is not clear. In this study, we focused on the effects of ripe Pu-erh tea aqueous extracts on the intestinal microbiota in an intestinal flora disorder mouse model. Physiological indexes and the tissue section staining results showed that feeding Pu-erh tea extract could help mice regain weight and alleviate intestinal inflammation. Further assessment of the intestinal microflora found that Pu-erh tea extract could promote the growth of intestinal probiotics and inhibit pathogenic bacteria, thereby achieving a treatment effect for enteritis. This study provides new evidence for the therapeutic effect of Pu-erh tea.

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