Epidemiology and Cost of Peste des Petits Ruminants (PPR) Eradication in Small Ruminants in the United Arab Emirates-Disease Spread and Control Strategies Simulations

Simple Summary Peste des petits ruminants (PPR), also known as sheep and goat plague, is a highly contagious animal disease affecting small ruminants and camels. It is caused by a virus belonging to the genus Morbillivirus, family Paramixoviridae. Once newly introduced, the virus can infect up to 90 percent of an animal herd. A PPR outbreak is an emergency due to its rapid spread and high animal mortality rate. This study simulated three control strategies of PPR spread among animals in the United Arab Emirates. These strategies include implementing mass vaccination, ring vaccination and ceased vaccination strategies, combined with or without strict animal movement control simultaneously. The simulation results compared the level of the effectiveness and direct government costs for each of the three strategies. Such results aid the decision-makers in the country and globally in line with the World Animal Health Organization's goal to eradicate the disease by 2030. Peste des petits ruminants (PPR) is an important infectious viral disease of domestic small ruminants that threatens the food security and sustainable livelihood of farmers across Middle East, Africa, and Asia. The objective of this research is to analyze the disease's spread and its impacts on direct government costs through conducting three simulations of different control strategies to reduce and quickly eradicate PPR from the United Arab Emirates in the near future. A Modified Animal Disease Spread Model was developed in this study to suit the conditions of the United Arab Emirates. The initial scenario represents when mass vaccination is ceased, and moderate movement restrictions are applied. The second scenario is based on mass vaccination and stamping out the disease, whereas the third simulation scenario assumes mass and ring vaccination when needed, very strict movement control, and stamping out. This study found that the third scenario is the most effective in controlling and eradicating PPR from the UAE. The outbreak duration in days was reduced by 57% and the number of infected animals by 77% when compared to the other scenarios. These results are valuable to the country's animal health decision-makers and the government's efforts to report to the World Animal Health Organization (OIE) regarding the progress made towards declaration of the disease's eradication. They are also useful to other concerned entities in other Middle Eastern, North African, and Asian countries where the disease is spreading.

Automated summary

Peste des petits ruminants (PPR) is a highly contagious animal disease affecting small ruminants and camels, with a high mortality rate. This study simulated three control strategies in the UAE, finding that the third strategy, which includes mass and ring vaccination along with strict movement control, was most effective in reducing outbreak duration and infected animals. The results are valuable for decision-makers and government efforts towards eradicating PPR and are relevant for other countries facing similar challenges.