Journal
CURRENT MOLECULAR PHARMACOLOGY
Volume 15, Issue 1, Pages 51-76Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1874467214666210910114324
Keywords
Traumatic brain injuries; Concussion; Parkinson's disease; Alzheimer's disease; Demntia; Nutraceuticals; Dietary supplements
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Sports play a significant role in human life, but contact sports can lead to brain injuries for athletes. These injuries can cause various dysfunctions and may even be related to chronic diseases. By studying post-concussion neurobehavioral changes, early detection signs, and improving neuropsychiatric diseases in athletes, we can better understand and address these issues.
Sports deserve a special place in human life to impart healthy and refreshing wellbeing. However, sports activities, especially contact sports, renders athlete vulnerable to brain injuries. Athletes participating in a contact sport like boxing, rugby, American football, wrestling, and basketball are exposed to traumatic brain injuries (TBI) or concussions. The acute and chronic nature of these heterogeneous injuries provides a spectrum of dysfunctions that alters the neuronal, musculoskeletal, and behavioral responses of an athlete. Many sports-related brain injuries go unreported, but these head impacts trigger neurometabolic disruptions that contribute to long-term neuronal impairment. The pathophysiology of post-concussion and its underlying mechanisms are undergoing intense research. It also shed light on chronic disorders like Parkinson's disease, Alzheimer's disease, and dementia. In this review, we examined post-concussion neurobehavioral changes, tools for early detection of signs, and their impact on the athlete. Further, we discussed the role of nutritional supplements in ameliorating neuropsychiatric diseases in athletes.
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