4.6 Review

A Review on Recent Progress in Machine Learning and Deep Learning Methods for Cancer Classification on Gene Expression Data

Journal

PROCESSES
Volume 9, Issue 8, Pages -

Publisher

MDPI
DOI: 10.3390/pr9081466

Keywords

machine learning; deep learning; cancer classification; biomarker; gene expression

Funding

  1. Ministry of Higher Education [RACER/1/2019/ICT02/UMP//3]
  2. Universiti Malaysia Pahang under RDU scheme [RDU192624]

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This paper discusses the importance of using data-driven models with predictive ability in medical and healthcare, particularly focusing on the application of machine learning (ML) and deep learning (DL) in cancer classification. While various methods have been applied to cancer classification, successful techniques mainly revolve around supervised and deep learning methods.
Data-driven model with predictive ability are important to be used in medical and healthcare. However, the most challenging task in predictive modeling is to construct a prediction model, which can be addressed using machine learning (ML) methods. The methods are used to learn and trained the model using a gene expression dataset without being programmed explicitly. Due to the vast amount of gene expression data, this task becomes complex and time consuming. This paper provides a recent review on recent progress in ML and deep learning (DL) for cancer classification, which has received increasing attention in bioinformatics and computational biology. The development of cancer classification methods based on ML and DL is mostly focused on this review. Although many methods have been applied to the cancer classification problem, recent progress shows that most of the successful techniques are those based on supervised and DL methods. In addition, the sources of the healthcare dataset are also described. The development of many machine learning methods for insight analysis in cancer classification has brought a lot of improvement in healthcare. Currently, it seems that there is highly demanded further development of efficient classification methods to address the expansion of healthcare applications.

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