Journal
PROCESSES
Volume 9, Issue 8, Pages -Publisher
MDPI
DOI: 10.3390/pr9081370
Keywords
Strobilanthes crispus; anticancer; bioactive compound; phytochemical; natural product
Categories
Funding
- Ministry of Higher Education, Malaysia [FRGS/1/2019/SKK08/MUSM/02/2]
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Cancer is a leading cause of death globally, and chemotherapy has many drawbacks, making the search for better anticancer drugs from natural sources crucial. S. crispus is a herbal medicinal plant with high vitamin and mineral content, as well as therapeutic phytochemicals, with numerous studies demonstrating its potential anticancer effects.
Cancer is a major cause of death worldwide, as exemplified by millions of cancer diagnoses every year. The use of chemotherapy in treating cancer has many disadvantages which include recurrence of cancer, associated with drug resistance, and severe side effects that are harmful to the patients. A better source of anticancer drugs can come from nature. Strobilanthes crispus (S. crispus) is a herbal medicinal plant that is indigenous in Madagascar and the Malay Archipelago. The plant possesses high vitamin and mineral content as well as phytochemicals-like phenols, catechins, tannins, and flavonoids-that are known to have therapeutic effects. Numerous preclinical studies have reported very versatile pharmacological effects of this plant, such as anticancer, antimicrobial, antioxidant, anti-angiogenesis, anti-diabetes, anti-ulcerogenic, and wound healing. Herein, this paper reviews the anticancer properties of S. crispus, providing information for future research and further exploration.
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