4.4 Article

Transmission of SARS-CoV-2 Alpha Variant (B.1.1.7) From a BNT162b2-Vaccinated Individual

Journal

OPEN FORUM INFECTIOUS DISEASES
Volume 8, Issue 8, Pages -

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofab369

Keywords

BNT162b2; SARS-CoV-2; transmission; vaccination

Funding

  1. Vaccine Research Institute
  2. IDEX AAP EMERGENCE-Universite de Paris (EMER-VEYER project)
  3. Mecenat COVID APHP-CUP

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This report describes a case of confirmed transmission of the SARS-CoV-2 alpha variant (B.1.1.7) from a symptomatic immunocompetent woman 4 weeks after her second dose of the BNT162b2 vaccine, despite antispike seroconversion.
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) acquisition after vaccination with BNT162b2 have been described, but the risk of secondary transmission from fully vaccinated individuals remains ill defined. Herein we report a confirmed transmission of SARS-CoV-2 alpha variant (B.1.1.7) from a symptomatic immunocompetent woman 4 weeks after her second dose of BNT162b2, despite antispike seroconversion.

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