Related references
Note: Only part of the references are listed.Targeting BTK Signaling in the Microenvironment of Solid Tumors as a Feasible Cancer Therapy Option
Justin K. Messex et al.
CANCERS (2021)
MM-129 as a Novel Inhibitor Targeting PI3K/AKT/mTOR and PD-L1 in Colorectal Cancer
Justyna Magdalena Hermanowicz et al.
CANCERS (2021)
Exploration of novel heterofused 1,2,4-triazine derivative in colorectal cancer
Justyna Magdalena Hermanowicz et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2021)
Use of Zebrafish in Drug Discovery Toxicology
Steven Cassar et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2020)
The Acute Effects of 5 Fluorouracil on Skeletal Muscle Resident and Infiltrating Immune Cells in Mice
Brandon N. VanderVeen et al.
FRONTIERS IN PHYSIOLOGY (2020)
The intensification of anticancer activity of LFM-A13 by erythropoietin as a possible option for inhibition of breast cancer
Dariusz Rozkiewicz et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2020)
Impact of 5 fluorouracil chemotherapy on gut inflammation, functional parameters, and gut microbiota
A. T. Sougiannis et al.
BRAIN BEHAVIOR AND IMMUNITY (2019)
In vivo toxicity assays in zebrafish embryos: a pre-requisite for xenograft preclinical studies
Carlha Gutierrez-Lovera et al.
TOXICOLOGY MECHANISMS AND METHODS (2019)
5-Fluorouracil induced liver toxicity in patients with colorectal cancer: role of computed tomography texture analysis as a potential biomarker
Francesco Alessandrino et al.
ABDOMINAL RADIOLOGY (2019)
Toxicity study on Clinacanthus nutans leaf hexane fraction using Danio rerio embryos
Suganya Murugesu et al.
TOXICOLOGY REPORTS (2019)
Simultaneous use of erythropoietin and LFM-A13 as a new therapeutic approach for colorectal cancer
Anna Tankiewicz-Kwedlo et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Synthesis, Structure and Antiproliferative Activity of New pyrazolo[4,3-e] triazolo[4,5-b][1,2,4] triazine Derivatives
Mariusz Mojzych et al.
MEDICINAL CHEMISTRY (2018)
An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds
Stella Cascioferro et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
The potential protective role of taurine against 5-fluorouracil-induced nephrotoxicity in adult male rats
Hany N. Yousef et al.
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY (2017)
Tris(1,3-dichloro-2-propyl) phosphate disrupts axonal growth, cholinergic system and motor behavior in early life zebrafish
Rui Cheng et al.
AQUATIC TOXICOLOGY (2017)
Toxicology Strategies for Drug Discovery: Present and Future
Eric A. G. Blomme et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2016)
Textile dyes induce toxicity on zebrafish early life stages
Gisele Augusto Rodrigues de Oliveira et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2016)
Effects of Cyclin Dependent Kinase 9 inhibition on zebrafish larvae
Gianfranco Matrone et al.
CELL CYCLE (2016)
Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity
R. Dixon Dorand et al.
SCIENCE (2016)
New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors
Mariusz Mojzych et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Antibiotic Toxicity and Absorption in Zebrafish Using Liquid Chromatography-Tandem Mass Spectrometry
Fan Zhang et al.
PLOS ONE (2015)
Mitigation of 5-Fluorouracil induced renal toxicity by chrysin via targeting oxidative stress and apoptosis in wistar rats
Summya Rashid et al.
FOOD AND CHEMICAL TOXICOLOGY (2014)
Liver Regeneration by Stem/Progenitor Cells
Tohru Itoh et al.
HEPATOLOGY (2014)
1,2,4-Triazine Analogs as Novel Class of Therapeutic Agents
Rajeev Kumar et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2014)
OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing
Francois Busquet et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2014)
Chemotherapy induced liver abnormalities: an imaging perspective
Ankush Sharma et al.
CLINICAL AND MOLECULAR HEPATOLOGY (2014)
Cardiovascular risk assessment of atypical antipsychotic drugs in a zebrafish model
Sung Hak Lee et al.
JOURNAL OF APPLIED TOXICOLOGY (2013)
Ibrutinib and novel BTK inhibitors in clinical development
Akintunde Akinleye et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2013)
Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor-CR8-in mice
Hatem Sallam et al.
BMC PHARMACOLOGY & TOXICOLOGY (2013)
Apoptosis and Necrosis in the Liver
Maria Eugenia Guicciardi et al.
COMPREHENSIVE PHYSIOLOGY (2013)
Dietary emu oil supplementation suppresses 5-fluorouracil chemotherapy-induced inflammation, osteoclast formation, and bone loss
Rethi Raghu Nadhanan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)
Prognostic value of chemotherapy-induced neutropenia in early-stage breast cancer
Yunwei Han et al.
BREAST CANCER RESEARCH AND TREATMENT (2012)
From Omics to Drug Metabolism and High Content Screen of Natural Product in Zebrafish: A New Model for Discovery of Neuroactive Compound
Ming Wai Hung et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2012)
Adverse Event Profiles of 5-Fluorouracil and Capecitabine: Data Mining of the Public Version of the FDA Adverse Event Reporting System, AERS, and Reproducibility of Clinical Observations
Kaori Kadoyama et al.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2012)
The toxic effect of Amiodarone on valve formation in the developing heart of zebrafish embryos
Ying-Hsin Chen et al.
REPRODUCTIVE TOXICOLOGY (2012)
Zebrafish embryos as an alternative to animal experiments-A commentary on the definition of the onset of protected life stages in animal welfare regulations
Uwe Straehle et al.
REPRODUCTIVE TOXICOLOGY (2012)
Concentration-Response Analysis of Differential Gene Expression in the Zebrafish Embryotoxicity Test Following Flusilazole Exposure
Sanne A. B. Hermsen et al.
TOXICOLOGICAL SCIENCES (2012)
Btk regulation in human and mouse B cells via protein kinase C phosphorylation of IBtkγ
Elzbieta Janda et al.
BLOOD (2011)
Chemotherapy-induced myelotoxicity and incidence of lung metastasis in an animal model
Jin-Young Son et al.
HUMAN & EXPERIMENTAL TOXICOLOGY (2011)
A Novel Xenograft Model in Zebrafish for High-Resolution Investigating Dynamics of Neovascularization in Tumors
Chengjian Zhao et al.
PLOS ONE (2011)
Zebrafish: A Complete Animal Model for In Vivo Drug Discovery and Development
Chiranjib Chakraborty et al.
CURRENT DRUG METABOLISM (2009)
Neutropaenia as a prognostic factor in metastatic colorectal cancer patients undergoing chemotherapy with first-line FOLFOX
Kohei Shitara et al.
EUROPEAN JOURNAL OF CANCER (2009)
Protein Profiles in Zebrafish (Danio rerio) Embryos Exposed to Perfluorooctane Sulfonate
Xiongjie Shi et al.
TOXICOLOGICAL SCIENCES (2009)
Severe adverse effects of 5-fluorouracil in S-1 were lessened by haemodialysis due to elimination of the drug
Kazunori Inoue et al.
CLINICAL KIDNEY JOURNAL (2009)
Effect of the Cdk-inhibitor roscovitine on mouse hematopoietic progenitors in vivo and in vitro
Hairong Song et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2007)
A phase I trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; R-Roscovitine), administered twice daily for 7 days every 21 days
C. Benson et al.
BRITISH JOURNAL OF CANCER (2007)
Effects of smoking on the pharmacokinetics of erlotinib
M Hamilton et al.
CLINICAL CANCER RESEARCH (2006)
Zebrafish as a model vertebrate for investigating chemical toxicity
AJ Hill et al.
TOXICOLOGICAL SCIENCES (2005)
Reversal of collapsing glomerulopathy in mice with the cyclin-dependent kinase inhibitor CYC202
D Gherardi et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2004)
Zebrafish: a model system for the study of human disease
K Dooley et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2000)
Synthesis and antimycobacterial activity of some 4H-1,2,4-triazin-5-one derivatives
MG Mamolo et al.
FARMACO (2000)