4.6 Article

Low Concordance Between T-Cell Densities in Matched Primary Tumors and Liver Metastases in Microsatellite Stable Colorectal Cancer

Related references

Note: Only part of the references are listed.
Review Oncology

Immunotherapy for the treatment of colorectal cancer

Melissa A. Lumish et al.

Summary: Immune checkpoint inhibition has shown high efficacy in colorectal cancer with mismatch-repair deficiency, while the response is poor in cases with preserved MMR/microsatellite stability. Besides studying the application of ICI in dMMR/MSI-H mCRC, attention should also be paid to its role in locally advanced disease, response biomarkers, and future targets.

JOURNAL OF SURGICAL ONCOLOGY (2021)

Article Oncology

Primary tumor immune score fails to predict the prognosis of colorectal cancer liver metastases after hepatectomy in Chinese populations

Hao-Cheng Lin et al.

Summary: The study investigated 131 Chinese patients with CRLM and found that the immune score of the primary tumor failed to predict the postoperative survival of liver metastases in these patients. Additionally, analysis of data from the Gene Expression Omnibus showed no significant correlation between the tumor-infiltrating T cell profiles of the primary tumor and liver metastases.

ANNALS OF TRANSLATIONAL MEDICINE (2021)

Article Pathology

Multi-center real-world comparison of the fully automated Idylla™ microsatellite instability assay with routine molecular methods and immunohistochemistry on formalin-fixed paraffin-embedded tissue of colorectal cancer

Ana Velasco et al.

Summary: The Idylla (TM) MSI Assay has a lower failure rate and high concordance levels compared to routine diagnostic tests.

VIRCHOWS ARCHIV (2021)

Review Oncology

Regulatory T cells in cancer immunosuppression - implications for anticancer therapy

Yosuke Togashi et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2019)

Article Medicine, General & Internal

Biomarker concordance between primary colorectal cancer and its metastases

D. S. Bhullar et al.

EBIOMEDICINE (2019)

Article Immunology

Obstacles to T cell migration in the tumor microenvironment

Alba Nicolas-Boluda et al.

COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES (2019)

Review Medicine, General & Internal

Colorectal cancer

Evelien Dekker et al.

LANCET (2019)

Review Oncology

The clinical role of the TME in solid cancer

Nicolas A. Giraldo et al.

BRITISH JOURNAL OF CANCER (2019)

Review Biotechnology & Applied Microbiology

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

Jerome Galon et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

Article Oncology

Comprehensive Intrametastatic Immune Quantification and Major Impact of Immunoscore on Survival

Bernhard Mlecnik et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)

Article Oncology

Comprehensive Intrametastatic Immune Quantification and Major Impact of Immunoscore on Survival

Bernhard Mlecnik et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)

Review Biochemistry & Molecular Biology

CD4 and CD8 T lymphocyte interplay in controlling tumor growth

Dmitrij Ostroumov et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Article Medicine, Research & Experimental

Colorectal cancer-infiltrating T lymphocytes display a distinct chemokine receptor expression profile

Ann-Britt Lofroos et al.

EUROPEAN JOURNAL OF MEDICAL RESEARCH (2017)

Editorial Material Medicine, Research & Experimental

The Immune Score as a New Possible Approach for the Classification of Cancer

Jerome Galon et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2012)

Review Multidisciplinary Sciences

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

Robert D. Schreiber et al.

SCIENCE (2011)

Article Oncology

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

E. A. Eisenhauer et al.

EUROPEAN JOURNAL OF CANCER (2009)