4.6 Review

Cellular Therapy via Spermatogonial Stem Cells for Treating Impaired Spermatogenesis, Non-Obstructive Azoospermia

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Preliminary study on testicular germ cell isolation and transplantation in an endangered endemic species Brycon orbignyanus (Characiformes: Characidae)

Diogenes Henrique de Siqueira-Silva et al.

Summary: The study established a simplified protocol for the transplantation of Brycon orbignyanus spermatogonial stem cells into Astyanax altiparanae testes, leading to successful xenogenic germ cell transplantation in sexually mature Characiformes fish species.

FISH PHYSIOLOGY AND BIOCHEMISTRY (2021)

Review Immunology

The impact of autoimmune systemic inflammation and associated medications on male reproductive health in patients with chronic rheumatological, dermatological, and gastroenterological diseases: A systematic review

Renata Finelli et al.

Summary: Autoimmune disorders and related treatments may adversely affect male fertility parameters, necessitating further research to develop appropriate guidelines.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2021)

Article Obstetrics & Gynecology

Fertility preservation for prepubertal boys: lessons learned from the past and update on remaining challenges towards clinical translation

Christine Wyns et al.

Summary: With the increase in childhood cancer incidence and survivorship, there is a growing interest in using cryopreserved immature testicular tissue for fertility preservation in prepubertal boys. Current research suggests that autotransplantation of frozen-thawed testicular tissue may be a feasible technique.

HUMAN REPRODUCTION UPDATE (2021)

Article Obstetrics & Gynecology

SCF Improves In Vitro Differentiation of SSCs Through Transcriptionally Up-regulating PRTM1, STRA8, c-KIT, PIWIL2, and OCT4 Genes

Mahnaz Nasimi et al.

Summary: The study found that SCF improves in vitro differentiation of SSCs in OA rats by transcriptionally upregulating PRTM1, STRA8, c-KIT, PIWIL2, and OCT4 genes.

REPRODUCTIVE SCIENCES (2021)

Review Biochemistry & Molecular Biology

Metabolic Requirements for Spermatogonial Stem Cell Establishment and Maintenance In Vivo and In Vitro

Anna Laura Voigt et al.

Summary: Spermatogonial stem cells are unique adult stem cells that play a crucial role in treating infertility. Understanding the factors necessary for their lifelong maintenance and in vitro expansion is essential for successful clinical applications. Metabolism is discussed as vital for cell biology, stem cell integrity, and decision-making in the context of SSC maintenance, differentiation, and expansion.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Multidisciplinary Sciences

Rat in vitro spermatogenesis promoted by chemical supplementations and oxygen-tension control

Takafumi Matsumura et al.

Summary: By modifying culture conditions and supplementing chemical substances, successful IVS of rats was achieved, maintaining rat spermatogenesis up to round spermatids over 70 days in culture. This progress is a significant step towards successful IVS in various animal species, including humans.

SCIENTIFIC REPORTS (2021)

Review Cell & Tissue Engineering

Mesenchymal stromal/stem cells and their exosomes for restoration of spermatogenesis in non-obstructive azoospermia: a systemic review

Rano Zhankina et al.

Summary: Stem cells, especially MSCs, have shown potential in treating reproductive diseases like NOA by differentiating into germ cells and even inducing spermatogenesis in infertile animal models. Despite these promising results, clinical trials on MSC therapy for NOA in men have not yet been completed.

STEM CELL RESEARCH & THERAPY (2021)

Article Andrology

Postpubertal spermatogonial stem cell transplantation restores functional sperm production in rhesus monkeys irradiated before and after puberty

Gunapala Shetty et al.

Summary: The study successfully restored sperm production in non-human primates who had undergone gonadotoxic treatment before and after puberty by transplanting cryopreserved testicular cells into the seminiferous tubules. In some monkeys, functional sperm derived from the donor were produced after transplantation, with pretreatment not significantly affecting the ability to recover donor-derived sperm production.

ANDROLOGY (2021)

Review Obstetrics & Gynecology

Review of injection techniques for spermatogonial stem cell transplantation

Murat Gul et al.

HUMAN REPRODUCTION UPDATE (2020)

Article Medicine, Research & Experimental

Hsa-miR-1908-3p Mediates the Self-Renewal and Apoptosis of Human Spermatogonial Stem Cells via Targeting KLF2

Wei Chen et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2020)

Article Cell & Tissue Engineering

Derivation and propagation of spermatogonial stem cells from human pluripotent cells

Huiming Xu et al.

STEM CELL RESEARCH & THERAPY (2020)

Review Environmental Sciences

Effects of environmental contaminants on fertility and reproductive health

Yanmin Ma et al.

JOURNAL OF ENVIRONMENTAL SCIENCES (2019)

Article Medicine, General & Internal

Paediatric and adult-onset male hypogonadism

Andrea Salonia et al.

NATURE REVIEWS DISEASE PRIMERS (2019)

Article Cell & Tissue Engineering

Does co-transplantation of mesenchymal and spermatogonial stem cells improve reproductive efficiency and safety in mice?

Prashant Kadam et al.

STEM CELL RESEARCH & THERAPY (2019)

Review Medical Laboratory Technology

Fertility and infertility: Definition and epidemiology

Melodie Vander Borght et al.

CLINICAL BIOCHEMISTRY (2018)

Review Cell Biology

Current approaches for the treatment of male infertility with stem cell therapy

Zahra Pourmoghadam et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2018)

Article Endocrinology & Metabolism

Decline in seminal quality in Indian men over the last 37 years

Priyanka Mishra et al.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2018)

Article Physiology

Haploid Germ Cells Generated in Organotypic Culture of Testicular Tissue From Prepubertal Boys

Francesca de Michele et al.

FRONTIERS IN PHYSIOLOGY (2018)

Article Veterinary Sciences

In vitro differentiation of spermatogonial stem cells using testicular cells from Guangxi Bama mini-pig

Huimin Zhao et al.

JOURNAL OF VETERINARY SCIENCE (2018)

Review Urology & Nephrology

Spermatogonial stem cell transplantation and male infertility: Current status and future directions

Connor M. Forbes et al.

ARAB JOURNAL OF UROLOGY (2018)

Article Urology & Nephrology

Lifestyle causes of male infertility

Damayanthi Durairajanayagam

ARAB JOURNAL OF UROLOGY (2018)

Article Obstetrics & Gynecology

The International Glossary on Infertility and Fertility Care, 2017

Fernando Zegers-Hochschild et al.

FERTILITY AND STERILITY (2017)

Review Obstetrics & Gynecology

Temporal trends in sperm count: a systematic review and meta-regression analysis

Hagai Levine et al.

HUMAN REPRODUCTION UPDATE (2017)

Review Obstetrics & Gynecology

Semen quality and alcohol intake: a systematic review and meta-analysis

Elena Ricci et al.

REPRODUCTIVE BIOMEDICINE ONLINE (2017)

Article Cell & Tissue Engineering

Enrichment and In Vitro Culture of Spermatogonial Stem Cells from Pre-Pubertal Monkey Testes

Yong-Hee Kim et al.

TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2017)

Review Andrology

The impact of drugs on male fertility: a review

M. Semet et al.

ANDROLOGY (2017)

Article Cell & Tissue Engineering

Enrichment and In Vitro Culture of Spermatogonial Stem Cells from Pre-Pubertal Monkey Testes

Yong-Hee Kim et al.

TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2017)

Article Medicine, Research & Experimental

Expansion and long-term culture of human spermatogonial stem cells via the activation of SMAD3 and AKT pathways

Ying Guo et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2015)

Article Obstetrics & Gynecology

On-label and off-label drugs used in the treatment of male infertility

Mahmoud Chehab et al.

FERTILITY AND STERILITY (2015)

Review Urology & Nephrology

Effects of psychological stress on male fertility

Vinod H. Nargund

NATURE REVIEWS UROLOGY (2015)

Article Endocrinology & Metabolism

Very small embryonic-like stem cells (VSELs) detected in azoospermic testicular biopsies of adult survivors of childhood cancer

Purna Kurkure et al.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2015)

Review Obstetrics & Gynecology

Causes, effects and molecular mechanisms of testicular heat stress

Damayanthi Durairajanayagam et al.

REPRODUCTIVE BIOMEDICINE ONLINE (2015)

Article Biochemistry & Molecular Biology

A Novel Feeder-Free Culture System for Expansion of Mouse Spermatogonial Stem Cells

Na Young Choi et al.

MOLECULES AND CELLS (2014)

Article Multidisciplinary Sciences

Offspring production with sperm grown in vitro from cryopreserved testis tissues

Tetsuhiro Yokonishi et al.

NATURE COMMUNICATIONS (2014)

Article Obstetrics & Gynecology

Time costs of fertility care: the hidden hardship of building a family

Alex K. Wu et al.

FERTILITY AND STERILITY (2013)

Review Biotechnology & Applied Microbiology

Propagation of Adult SSCs: From Mouse to Human

Laura A. Martin et al.

BIOMED RESEARCH INTERNATIONAL (2013)

Article Biotechnology & Applied Microbiology

Recovery of Fertility in Azoospermia Rats after Injection of Adipose-Tissue-Derived Mesenchymal Stem Cells: The Sperm Generation

Cihangir Cakici et al.

BIOMED RESEARCH INTERNATIONAL (2013)

Article Andrology

Hormonal Imbalances and Psychological Scars Left Behind in Infertile Men

Chong Won Bak et al.

JOURNAL OF ANDROLOGY (2012)

Article Multidisciplinary Sciences

Testis tissue explantation cures spermatogenic failure in c-Kit ligand mutant mice

Takuya Sato et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Endocrinology & Metabolism

Male infertility: Pathogenesis and clinical diagnosis

Csilla Krausz

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2011)

Review Andrology

Human spermatogonial stem cells: a possible origin for spermatocytic seminoma

R. Waheeb et al.

INTERNATIONAL JOURNAL OF ANDROLOGY (2011)

Article Multidisciplinary Sciences

In vitro production of functional sperm in cultured neonatal mouse testes

Takuya Sato et al.

NATURE (2011)

Article Endocrinology & Metabolism

Isolation and characterization of human spermatogonial stem cells

Shixue Liu et al.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2011)

Article Developmental Biology

Testicular Gene Expression in Cryptorchid Boys at Risk of Azoospermia

F. Hadziselimovic et al.

SEXUAL DEVELOPMENT (2011)

Article Reproductive Biology

Isolation, Characterization, and Culture of Human Spermatogonia

Zuping He et al.

BIOLOGY OF REPRODUCTION (2010)

Article Obstetrics & Gynecology

Complicity in stem cell research: the case of induced pluripotent stem cells

Katrien Devolder

HUMAN REPRODUCTION (2010)

Review Biology

Spermatogonial stem cell regulation and spermatogenesis

Bart T. Phillips et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2010)

Article Obstetrics & Gynecology

Infertility services reported by men in the United States: national survey data

John E. Anderson et al.

FERTILITY AND STERILITY (2009)

Article Anatomy & Morphology

The Spermatogonial Stem Cell Niche

Dirk G. De Rooij

MICROSCOPY RESEARCH AND TECHNIQUE (2009)

Article Multidisciplinary Sciences

Phenotypic Plasticity of Mouse Spermatogonial Stem Cells

Hiroko Morimoto et al.

PLOS ONE (2009)

Article Andrology

Chronic orchitis: a neglected cause of male infertility?

H. -C. Schuppe et al.

ANDROLOGIA (2008)

Article Obstetrics & Gynecology

The management of infertility due to obstructive azoospermia

FERTILITY AND STERILITY (2008)

Review Biochemistry & Molecular Biology

The biology of infertility: research advances and clinical challenges

Martin M. Matzuk et al.

NATURE MEDICINE (2008)

Article Agriculture, Dairy & Animal Science

Regulation of the spermatogonial stem cell niche

N. Kostereva et al.

REPRODUCTION IN DOMESTIC ANIMALS (2008)

Article Urology & Nephrology

Hormonal evaluation of the infertile male: Has it evolved?

Ernest M. Sussman et al.

UROLOGIC CLINICS OF NORTH AMERICA (2008)

Review Urology & Nephrology

Endocrine manipulation in male infertility

Howard H. Kim et al.

UROLOGIC CLINICS OF NORTH AMERICA (2008)

Article Multidisciplinary Sciences

Generation of functional multipotent adult stem cells from GPR125+ germline progenitors

Marco Seandel et al.

NATURE (2007)

Review Obstetrics & Gynecology

Male infertility: role of genetic background

Alberto Ferlin et al.

REPRODUCTIVE BIOMEDICINE ONLINE (2007)

Article Medicine, General & Internal

Age at surgery for undescended testis and risk of testicular cancer

Andreas Pettersson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Article Obstetrics & Gynecology

Effect of chemo- or radiotherapy on sperm parameters of testicular cancer patients

Loredana Gandini et al.

HUMAN REPRODUCTION (2006)

Article Multidisciplinary Sciences

Pluripotency of spermatogonial stem cells from adult mouse testis

K Guan et al.

NATURE (2006)

Article Pediatrics

Testicular torsion and risk factors for orchiectomy

JM Mansbach et al.

ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE (2005)

Article Obstetrics & Gynecology

Germline niche transplantation restores fertility in infertile mice

M Kanatsu-Shinohara et al.

HUMAN REPRODUCTION (2005)

Review Obstetrics & Gynecology

Molecular pathology of the CFTR locus in male infertility

M Claustres

REPRODUCTIVE BIOMEDICINE ONLINE (2005)

Article Obstetrics & Gynecology

Restoration of fertility in infertile mice by transplantation of cryopreserved male germline stem cells

M Kanatsu-Shinohara et al.

HUMAN REPRODUCTION (2003)

Article Obstetrics & Gynecology

Completion of meiosis in human primary spermatocytes through in vitro coculture with Vero cells

A Tanaka et al.

FERTILITY AND STERILITY (2003)

Review Obstetrics & Gynecology

The present and future state of hormonal treatment for male infertility

PY Liu et al.

HUMAN REPRODUCTION UPDATE (2003)

Review Urology & Nephrology

Comprehensive office evaluation in the new millennium

PJ Burrows et al.

UROLOGIC CLINICS OF NORTH AMERICA (2002)

Review Urology & Nephrology

A new look at the medical management of infertility

FM Siddiq et al.

UROLOGIC CLINICS OF NORTH AMERICA (2002)

Article Urology & Nephrology

Diagnosis and treatment of ejaculatory dysfunction

TG Schuster et al.

UROLOGIC CLINICS OF NORTH AMERICA (2002)

Article Urology & Nephrology

The diagnosis and treatment of the azoospermic patient in the age of intracytoplasmic sperm injection

CV Hopps et al.

UROLOGIC CLINICS OF NORTH AMERICA (2002)

Article Environmental Sciences

The question of declining sperm density revisited: An analysis of 101 studies published 1934-1996

SH Swan et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2000)

Article Oncology

Persistent altered spermatogenesis in long-term childhood cancer survivors

JAL Andreu et al.

PEDIATRIC HEMATOLOGY AND ONCOLOGY (2000)