4.7 Review

Management of Cataract in Patients with Age-Related Macular Degeneration

Journal

JOURNAL OF CLINICAL MEDICINE
Volume 10, Issue 12, Pages -

Publisher

MDPI
DOI: 10.3390/jcm10122538

Keywords

cataract surgery; age-related macular degeneration; clinical trials; real-world evidence

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Cataract and AMD are two common eye diseases in the elderly. Surgery can improve quality of life and reduce fall risk. Pre-operative OCT is recommended, and patients need careful counseling on expected outcomes and risks.
Cataract and age-related macular degeneration (AMD) are two of the most common eye diseases of aging. This review addresses the pre-operative, intra-operative, and post-operative considerations in managing cataract in patients with age-related macular degeneration. Surgery for visually significant cataracts in patients with AMD can substantially improve the quality of life and reduce the risk of falls. Pre-operative optical coherence tomography is now recommended where possible to identify pre-existing macula disease. Careful counselling of patients is required before cataract surgery, especially with respect to the expected visual outcome, intraocular lens choice and potential risks of surgery. Real-world data has suggested 6 months of intravitreal anti-VEGF therapy for neovascular AMD before cataract surgery is compatible with optimum long-term visual outcomes. Patients receiving intravitreal therapy for neovascular AMD should be advised of the slightly higher risk of intraoperative complications and the surgeon should be prepared to manage these during the operation. During cataract surgery, unnecessary light exposure should be avoided to reduce phototoxicity. Careful planning of intravitreal therapy for neovascular AMD just before cataract surgery allows the eye greater recovery time in the post-operative period before further planned intravitreal therapy.

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