Evaluation of Frailty Syndrome and Adherence to Recommendations in Elderly Patients with Hypertension

Frailty syndrome (FS) often coexists with many diseases of the elderly, including arterial hypertension, and may affect the disease course and adherence to therapeutic recommendations. This study aimed to evaluate the relationship between frailty and adherence to therapeutic recommendations in elderly hypertensive patients. The study included 259 patients hospitalized between January 2019 and November 2020 due to exacerbation of hypertension symptoms. Medical records were used to obtain basic sociodemographic and clinical data. The study was based on the Tilburg Frailty Indicator (TFI) and the Hill-Bone Scale (HBCS). The obtained data were analyzed within a cross-sectional design. The mean frailty score indicated by the TFI questionnaire was 7.09 +/- 3.73. The most prominent FS component was associated with the physical domain (4.24 +/- 2.54). The mean overall adherence measured with the HBCS was 20.51 +/- 3.72. The linear regression model testing the Hill-Bone reduced sodium intake score against the TFI domains showed no relationships between the variables. Another regression model for the Hill-Bone appointment-keeping subscale indicated significant predictors for physical and social TFI domains (p = 0.002 and p < 0.0001, respectively). For the Hill-Bone taking antihypertensive drugs variable, the regression model found significant relationships with all TFI domains: physical (p < 0.0001), psychological (p = 0.003) and social (p < 0.0001). Our study suggests that frailty in patients with arterial hypertension can negatively impact their adherence to therapeutic recommendations.

Automated summary

This study on 259 elderly hypertensive patients found that frailty syndrome may negatively impact patients' adherence to therapeutic recommendations, especially in physical and social domains. However, there was no relationship observed between reduced sodium intake and frailty indicators.