Antibody responses after a single dose of ChAdOx1 nCoV-19 vaccine in healthcare workers previously infected with SARS-CoV-2

Letter Medicine, General & Internal

Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2

Saman Saadat et al.

Summary: This study compared the titers of binding and neutralizing antibodies in healthcare workers previously infected with SARS-CoV-2 after receiving a single dose of mRNA coronavirus vaccine.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Letter Medicine, General & Internal

Antibody response to first BNT162b2 dose in previously SARS-CoV-2-infected individuals

Charlotte Manisty et al.

LANCET (2021)

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Letter Medicine, General & Internal

Antibody Responses in Seropositive Persons after a Single Dose of SARS-CoV-2 mRNA Vaccine

Florian Krammer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Infectious Diseases

Single-dose BNT162b2 mRNA COVID-19 vaccine significantly boosts neutralizing antibody response in health care workers recovering from asymptomatic or mild natural SARS-CoV-2 infection

Ilaria Vicenti et al.

Summary: Vaccination after infection can boost neutralizing antibody levels significantly higher than in uninfected individuals. Asymptomatic individuals with previous infection show a significant increase in neutralizing antibody titres after receiving the first vaccine dose.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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Letter Medicine, General & Internal

Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers

Sebastian Havervall et al.

Summary: This study found that COVID-19-related symptoms can persist for 8 months among Swedish health care workers, and these symptoms have effects on their home, work, and social functions.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Letter Medicine, General & Internal

Spike Antibody Levels of Nursing Home Residents With or Without Prior COVID-19 3 Weeks After a Single BNT162b2 Vaccine Dose

Hubert Blain et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Article Multidisciplinary Sciences

Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose

Catherine J. Reynolds et al.

Summary: Vaccination with a single dose of BNT162b2 after prior infection with a heterologous variant substantially enhances neutralizing antibody responses against variants. In contrast, individuals without prior infection showed reduced immunity against variants after receiving a single vaccine dose.

SCIENCE (2021)

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Article Immunology

Distinct antibody and memory B cell responses in SARS-CoV-2 naive and recovered individuals after mRNA vaccination

Rishi R. Goel et al.

Summary: mRNA vaccines exhibit robust serological and cellular priming, with naïve individuals requiring two doses for optimal antibody responses, especially against the B.1.351 variant. Memory B cells specific for spike protein and RBD were efficiently primed by vaccination, while recovered individuals showed significant boosting after the first dose, correlating with preexisting memory B cell levels. Identifying distinct responses based on prior SARS-CoV-2 exposure suggests that recovered subjects may only need one vaccine dose for peak responses, which can inform vaccine distribution strategies in resource-limited settings.

SCIENCE IMMUNOLOGY (2021)

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Article Dentistry, Oral Surgery & Medicine

COVID-19: Seroprevalence and Vaccine Responses in UK Dental Care Professionals

A. M. Shields et al.

Summary: Dental care professionals are at increased risk of SARS-CoV-2 infection, but serological response can provide protection. Natural infection leads to a sustained serological response, and vaccination results in a quicker and stronger antibody response.

JOURNAL OF DENTAL RESEARCH (2021)

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Article Immunology

Long-term antibody persistence and exceptional vaccination response on previously SARS-CoV-2 infected subjects

Davide Ferrari et al.

Summary: The study found that individuals previously infected with COVID-19 had significantly higher levels of antibodies after vaccination compared to those who had never been infected. Seropositivity persisted for at least 11 months after vaccination, suggesting that in times of vaccine shortage, priority should be given to individuals who have not been infected with the virus.

VACCINE (2021)

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Letter Medicine, General & Internal

SARS-CoV-2 vaccines for all but a single dose for COVID-19 survivors

Matthew Frieman et al.

EBIOMEDICINE (2021)

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Article Multidisciplinary Sciences

SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden

Ann-Sofie Rudberg et al.

NATURE COMMUNICATIONS (2020)

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Antibody responses after a single dose of ChAdOx1 nCoV-19 vaccine in healthcare workers previously infected with SARS-CoV-2

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