Microwave-Assisted CH Activation of the Thiophene Ring: A Simple Approach to Access Substituted Thienopyridines

A practical microwave-assisted CH activation for the preparation of several phenoxythieno[3,2-b]pyridines is reported here. This new strategy is an efficient alternative to the conventional methods currently used. The optimized conditions can also be applied to a one-pot approach.

Automated summary

This paper presents a practical microwave-assisted CH activation method for the synthesis of phenoxythieno[3,2-b]pyridines, offering an efficient alternative to conventional methods currently used and suitable for one-pot synthesis.