4.6 Review

In Planta Nanosensors: Understanding Biocorona Formation for Functional Design

Journal

ACS SENSORS
Volume 6, Issue 8, Pages 2802-2814

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acssensors.1c01159

Keywords

Nanosensor; biocorona; in planta; engineered nanomaterial; agricultural engineering

Funding

  1. IGI LGR ERA
  2. GlaxoSmithKline
  3. Citris/Banatao Seed Funding
  4. Burroughs Wellcome Fund Career Award at the Scientific Interface (CASI)
  5. Dreyfus foundation award
  6. Stanley Fahn PDF Junior Faculty Grant [PF-JFA-1760]
  7. Beckman Foundation Young Investigator Award
  8. NIH MIRA award
  9. NSF CAREER award
  10. NSF CBET award
  11. NSF CGEM award
  12. FFAR Young Investigator award
  13. CZI investigator award
  14. Sloan Foundation Award
  15. USDA BBT EAGER award
  16. USDA NIFA Award
  17. Moore Foundation Award
  18. Cisco Research Center grant
  19. DARPA Young Investigator Award
  20. National Science Foundation Graduate Research Fellowship [NSF DGE 1752814]
  21. Foundation for Food and Agriculture Research (FFAR) Fellows program

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As climate change and population growth strain agricultural output, monitoring and engineering of crops are increasingly necessary to meet the growing demand for food and energy. Nanoparticle-based sensors have emerged as new tools to advance agricultural practices, where understanding nanoparticle-biomolecule interactions in plants is essential for successful development and application of these sensors.
Climate change and population growth are straining agricultural output. To counter these changes and meet the growing demand for food and energy, the monitoring and engineering of crops are becoming increasingly necessary. Nanoparticle-based sensors have emerged in recent years as new tools to advance agricultural practices. As these nanoparticle-based sensors enter and travel through the complex biofluids within plants, biomolecules including proteins, metabolites, lipids, and carbohydrates adsorb onto the nanoparticle surfaces, forming a coating known as the bio-corona. Understanding these nanoparticle-biomolecule interactions that govern nanosensor function in plants will be essential to successfully develop and translate nanoparticle-based sensors into broader agricultural practice.

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