Journal
FRONTIERS IN PEDIATRICS
Volume 9, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fped.2021.645063
Keywords
SARS-CoV-2 infection; T cell activation; inflammatory activation; cystic fibrosis; cytokines
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Funding
- Fondazione Cariplo
- Regione Lombardia
- Fondazione Umberto Veronesi [2020-1355, 2020-1376]
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The study compared inflammatory markers in CF patients with and without COVID-19, aiming to understand the changes in inflammation levels during the pandemic in individuals with cystic fibrosis.
Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, data registered in the European countries revealed increasing cases of infection in cystic fibrosis (CF) patients. In the course of this pandemic, we enrolled 17 CF patients for a study evaluating inflammatory markers. One of them developed COVID-19, giving us the possibility to analyze inflammatory markers in the acute phase as compared to levels detected before and after the infectious episode and to levels measured in the other CF patients enrolled to the study who did not experience COVID-19 and 23 patients referred to our center for SARS-CoV-2 infection.
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