4.6 Review

Genetic and Environmental Determinants of T Helper 17 Pathogenicity in Spondyloarthropathies

Related references

Note: Only part of the references are listed.
Article Immunology

Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93

Jinling Huang et al.

Summary: The poorly understood member IL-17D in the IL-17 family plays a crucial role in maintaining intestinal homeostasis by regulating ILC3 function. Its deficiency leads to increased susceptibility to colitis, bacterial infection, and colon cancer. IL-17D binds CD93, a glycoprotein on mature ILC3s, and the IL-17D-CD93 axis is crucial in preserving intestinal health.

IMMUNITY (2021)

Article Medicine, Research & Experimental

TYK2 inhibition reduces type 3 immunity and modifies disease progression in murine spondyloarthritis

Eric Gracey et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Review Immunology

The IL-17 Family of Cytokines in Health and Disease

Mandy J. McGeachy et al.

IMMUNITY (2019)

Article Rheumatology

Association of synovial tissue polyfunctional T-cells with DAPSA in psoriatic arthritis

Sarah M. Wade et al.

ANNALS OF THE RHEUMATIC DISEASES (2019)

Review Rheumatology

The ties that bind: skin, gut and spondyloarthritis

Eric Gracey et al.

CURRENT OPINION IN RHEUMATOLOGY (2019)

Review Rheumatology

IL-17 in the immunopathogenesis of spondyloarthritis

Leonie S. Taams et al.

NATURE REVIEWS RHEUMATOLOGY (2018)

Article Multidisciplinary Sciences

Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases

Ariane Hammitzsch et al.

SCIENTIFIC REPORTS (2018)

Article Multidisciplinary Sciences

Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis

M. H. Al-Mossawi et al.

NATURE COMMUNICATIONS (2017)

Article Immunology

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Jason D. Fontenot et al.

JOURNAL OF IMMUNOLOGY (2017)

Article Immunology

Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity

Yasuhiro Kishi et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2016)

Article Biochemistry & Molecular Biology

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity

Jellert T. Gaublomme et al.

Article Biochemistry & Molecular Biology

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

Chao Wang et al.

Article Multidisciplinary Sciences

TH17 cells transdifferentiate into regulatory T cells during resolution of inflammation

Nicola Gagliani et al.

NATURE (2015)

Review Gastroenterology & Hepatology

Interleukin 23 in Crohn's Disease

Ahmet Eken et al.

INFLAMMATORY BOWEL DISEASES (2014)

Review Genetics & Heredity

Genomic modulators of the immune response

Julian C. Knight

TRENDS IN GENETICS (2013)

Article Biochemistry & Molecular Biology

A Validated Regulatory Network for Th17 Cell Specification

Maria Ciofani et al.

Article Immunology

Microbial-Induced Th17: Superhero or Supervillain?

Mandy J. McGeachy et al.

JOURNAL OF IMMUNOLOGY (2012)

Article Multidisciplinary Sciences

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

Christina E. Zielinski et al.

NATURE (2012)

Article Immunology

Induction and molecular signature of pathogenic TH17 cells

Youjin Lee et al.

NATURE IMMUNOLOGY (2012)

Article Immunology

Fate mapping of IL-17-producing T cells in inflammatory responses

Keiji Hirota et al.

NATURE IMMUNOLOGY (2011)

Article Multidisciplinary Sciences

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

Kamran Ghoreschi et al.

NATURE (2010)

Article Multidisciplinary Sciences

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

Kiran Nistala et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivaylo I. Ivanov et al.

Article Immunology

Late Developmental Plasticity in the T Helper 17 Lineage

Yun Kyung Lee et al.

IMMUNITY (2009)

Article Multidisciplinary Sciences

The AP-1 transcription factor Batf controls TH17 differentiation

Barbara U. Schraml et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

Hania Kebir et al.

NATURE MEDICINE (2007)

Article Biochemistry & Molecular Biology

STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

Xuexian O. Yang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Multidisciplinary Sciences

Transforming growth factor-β induces development of the TH17 lineage

PR Mangan et al.

NATURE (2006)

Article Immunology

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

CL Langrish et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2005)

Article Immunology

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

JD Fontenot et al.

NATURE IMMUNOLOGY (2003)

Article Biochemistry & Molecular Biology

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

S Aggarwal et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)