Journal
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
Volume 8, Issue 8, Pages 1760-1763Publisher
WILEY
DOI: 10.1002/acn3.51413
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- Projekt DEAL
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This case presents a rare dual diagnosis of sarcoidosis and neuromyelitis optica with aquaporin-4 antibodies in a patient with atypical recurrent optic neuritis. Long-term immunosuppression is required for management, highlighting the importance of identifying the features and cause of atypical optic neuritis.
We present a case of atypical recurrent optic neuritis. A man in his 50s presented with right optic neuritis and profound visual loss, associated with elevated inflammatory markers. Lymph-node biopsy was consistent with sarcoidosis. Aquaporin-4 antibodies were also present. Three months following corticosteroid treatment, his right optic neuritis relapsed, again with raised inflammatory markers. He was started on azathioprine and prednisolone with good effect. A dual diagnosis of sarcoidosis and neuromyelitis optica with aquaporin-4 antibodies is very rare. Long-term immunosuppression is required. The case highlights the importance of identifying the features and cause of atypical optic neuritis.
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