Journal
MATERIALS & DESIGN
Volume 204, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.matdes.2021.109672
Keywords
Noble metals; Implants; Coatings; Nanoparticles; Antibacterial properties; Biocompatible materials
Categories
Funding
- RSF [20-15-00222]
- Russian Science Foundation [20-15-00222] Funding Source: Russian Science Foundation
Ask authors/readers for more resources
This review discusses the use of noble metals and silver and gold nanoparticles to improve the performance of medical implants in orthopedic and reconstructive surgery. It analyzes the current use and limitations of traditional biomaterials, while exploring alternative solutions. The focus is on the analysis of noble metals as biocompatible and antibacterial materials, and the importance of modifying implant surfaces with thin films and nanoparticles for future implant development.
This review provides information on the use of noble metals, as well as silver and gold nanoparticles to improve the performance of medical implants related to orthopedic and reconstructive surgery. Traditionally, modern biomaterials used for implantation in various fields of medicine are metals and alloys, ceramics, carbon materials, polymers and composites. The existing limitations for the practical application of these materials are also analyzed and various alternatives are discussed. The main attention is paid to the analysis of experimental results on investigation of noble metals (Ir, Pt, Pd, Ag, Au) as multifunctional biocompatible and antibacterial materials in medical practice. In contrast to recent reviews that discussed individual classes of implantable materials or properties and applications of metal nanoparticles, this review attempts to generalize data on the modification of implant surfaces by thin films of platinum group metals and silver or gold nanoparticles. The formation of the implant of the future requires a comprehensive approach and solution of interrelated tasks, including selection of effective implant materials and methods of implant surface modification. This review is expected to promote further interest of researchers who are involved in the current level of evaluation and selection of modern biomaterials for medical implant applications. (C) 2021 The Author(s). Published by Elsevier Ltd.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available