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Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis
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The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and-2
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LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice
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Rosalind A. Coleman et al.
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Hepatic Free Cholesterol Accumulates in Obese, Diabetic Mice and Causes Nonalcoholic Steatohepatitis
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Adipose Triglyceride Lipase Is a Major Hepatic Lipase That Regulates Triacylglycerol Turnover and Fatty Acid Signaling and Partitioning
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Deficiency of Liver Adipose Triglyceride Lipase in Mice Causes Progressive Hepatic Steatosis
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The role of lipid droplets in metabolic disease in rodents and humans
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Endoplasmic reticulum stress in liver disease
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Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome
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Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria
Hong Wang et al.
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Lipid body formation during maturation of human mast cells
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Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption
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Activity-based Protein Profiling Identifies a Host Enzyme, Carboxylesterase 1, Which Is Differentially Active during Hepatitis C Virus Replication
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Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways
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Lipid droplet-associated PAT-proteins show frequent and differential expression in neoplastic steatogenesis
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Altered Lipid Droplet Dynamics in Hepatocytes Lacking Triacylglycerol Hydrolase Expression
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MOLECULAR BIOLOGY OF THE CELL (2010)
Peroxisome Proliferator-Activated Receptor Alpha Target Genes
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Long-Term Follow-Up of Patients With Nonalcoholic Fatty Liver
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CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2009)
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HEPATOLOGY (2009)
Liver-specific Loss of Long Chain Acyl-CoA Synthetase-1 Decreases Triacylglycerol Synthesis and β-Oxidation and Alters Phospholipid Fatty Acid Composition
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Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes
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Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor α activity
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Autophagy regulates lipid metabolism
Rajat Singh et al.
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Anna Kotronen et al.
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Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects
Kevin M. Korenblat et al.
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Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease
Puneet Puri et al.
GASTROENTEROLOGY (2008)
Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase-deficient mice
Montserrat Pinent et al.
GENOMICS (2008)
Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis
Beate Katharina Straub et al.
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AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase
Yan Qun Chen et al.
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Relationship of steatosis grade and zonal location to histological features of steatohepatitis in adult patients with non-alcoholic fatty liver disease
Naga Chalasani et al.
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Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis
Motohiro Sekiya et al.
JOURNAL OF LIPID RESEARCH (2008)
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
Stefano Romeo et al.
NATURE GENETICS (2008)
Effect of liver fat on insulin clearance
Anna Kotronen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
A lipidomic analysis of nonalcoholic fatty liver disease
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Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance
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Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects
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Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver
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Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide
Yumi Imai et al.
GASTROENTEROLOGY (2007)
Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice
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EXPERIMENTAL AND MOLECULAR PATHOLOGY (2007)
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis
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HEPATOLOGY (2007)
Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells
Yuren Wei et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)
Adipose triglyceridelipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome
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Contributions of different fatty acid sources to very low-density lipoprotein-triacylglycerol in the fasted and fed states
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Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis
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Mechanisms of Disease:: adipocytokines and visceral adipose tissue -: emerging role in nonalcoholic fatty liver disease
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Free fatty acids and Cytokines induce pancreatic β-cell apoptosis by different mechanisms:: Role of nuclear factor-κB and endoplasmic reticulum stress
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