4.8 Article

Spontaneously Resolving Joint Inflammation Is Characterised by Metabolic Agility of Fibroblast-Like Synoviocytes

Related references

Note: Only part of the references are listed.
Editorial Material Oncology

Whole-genome sequencing of East Asian lung cancers reveals new germline pathogenic variants

Semanti Mukherjee et al.

Summary: In this study, Wang et al. used whole-genome sequencing to comprehensively analyze common and rare variants associated with lung cancer risk in individuals with East Asian ancestry. Their findings suggest that rare promoter variants in the BRCA2 gene are associated with an increased risk of lung cancer.

CANCER CELL (2022)

Article Immunology

The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts

Jasna Friscic et al.

Summary: Inflammation-mediated tissue priming causes recurrence and worsening of arthritis, involving molecular and cellular mechanisms. This priming occurs locally and independently of adaptive immunity, and can be enhanced by activating complement C3 and C3a receptor, along with other molecular pathways, to boost cellular metabolic activity and increase inflammation sensitivity.

IMMUNITY (2021)

Review Immunology

Mitochondria as Key Players in the Pathogenesis and Treatment of Rheumatoid Arthritis

Sally A. Clayton et al.

Summary: Mitochondria play a crucial role in the pathogenesis of rheumatoid arthritis by affecting immune and non-immune cell function. Modulation of mitochondrial activity is a key therapeutic strategy for the disease. Mitochondrial components can directly stimulate immune receptors and contribute to sterile inflammation.

FRONTIERS IN IMMUNOLOGY (2021)

Article Endocrinology & Metabolism

A pipeline for multidimensional confocal analysis of mitochondrial morphology, function, and dynamics in pancreatic β-cells

Ahsen Chaudhry et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2020)

Review Physiology

Metabolic Checkpoints in Rheumatoid Arthritis

Valentina Pucino et al.

FRONTIERS IN PHYSIOLOGY (2020)

Review Immunology

Defining trained immunity and its role in health and disease

Mihai G. Netea et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Article Multidisciplinary Sciences

Distinct fibroblast subsets drive inflammation and damage in arthritis

Adam P. Croft et al.

NATURE (2019)

Review Immunology

Altered metabolic pathways regulate synovial inflammation in rheumatoid arthritis

U. Fearon et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2019)

Review Rheumatology

Synovial Cell Metabolism and Chronic Inflammation in Rheumatoid Arthritis

Jane Falconer et al.

ARTHRITIS & RHEUMATOLOGY (2018)

Article Cardiac & Cardiovascular Systems

Vascular mitochondrial respiratory function: the impact of advancing age

Soung Hun Park et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018)

Article Rheumatology

Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis

Marta F. Bustamante et al.

ANNALS OF THE RHEUMATIC DISEASES (2018)

Review Biochemistry & Molecular Biology

Implications of glycerol metabolism for lipid production

Lu-Lu Xue et al.

PROGRESS IN LIPID RESEARCH (2017)

Article Geriatrics & Gerontology

Functionally and morphologically damaged mitochondria observed in auditory cells under senescence-inducing stress

Teru Kamogashira et al.

NPJ AGING AND MECHANISMS OF DISEASE (2017)

Review Immunology

Immunometabolism governs dendritic cell and macrophage function

Luke A. J. O'Neill et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2016)

Article Rheumatology

Dysregulated bioenergetics: a key regulator of joint inflammation

M. Biniecka et al.

ANNALS OF THE RHEUMATIC DISEASES (2016)

Review Biochemistry & Molecular Biology

The Mitochondrial Basis of Aging

Nuo Sun et al.

MOLECULAR CELL (2016)

Review Rheumatology

Metabolomics in rheumatic diseases: desperately seeking biomarkers

Monica Guma et al.

NATURE REVIEWS RHEUMATOLOGY (2016)

Article Multidisciplinary Sciences

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

Erin Quan Toyama et al.

SCIENCE (2016)

Article Rheumatology

Critical Role of Glucose Metabolism in Rheumatoid Arthritis Fibroblast-like Synoviocytes

Ricard Garcia-Carbonell et al.

ARTHRITIS & RHEUMATOLOGY (2016)

Review Cell Biology

Redox Homeostasis and Mitochondrial Dynamics

Peter H. G. M. Willems et al.

CELL METABOLISM (2015)

Article Rheumatology

Choline kinase inhibition in rheumatoid arthritis

M. Guma et al.

ANNALS OF THE RHEUMATIC DISEASES (2015)

Article Cell Biology

Lipid Mediators in the Resolution of Inflammation

Charles N. Serhan et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Metabolic Reprogramming of Macrophages GLUCOSE TRANSPORTER 1 (GLUT1)-MEDIATED GLUCOSE METABOLISM DRIVES A PROINFLAMMATORY PHENOTYPE

Alex J. Freemerman et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

Serum Metabolomic Response of Myasthenia Gravis Patients to Chronic Prednisone Treatment

Manjistha Sengupta et al.

PLOS ONE (2014)

Article Gastroenterology & Hepatology

Serum and urine metabolomic fingerprinting in diagnostics of inflammatory bowel diseases

Tomasz Dawiskiba et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Review Biochemistry & Molecular Biology

The Warburg effect then and now: From cancer to inflammatory diseases

Eva M. Palsson-McDermott et al.

BIOESSAYS (2013)

Review Rheumatology

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

Nunzio Bottini et al.

NATURE REVIEWS RHEUMATOLOGY (2013)

Article Multidisciplinary Sciences

Fueling Immunity: Insights into Metabolism and Lymphocyte Function

E. L. Pearce et al.

SCIENCE (2013)

Editorial Material Biochemistry & Molecular Biology

Targeting cancer metabolism: a bedside lesson

Kivanc Birsoy et al.

NATURE MEDICINE (2012)

Article Biochemical Research Methods

Fiji: an open-source platform for biological-image analysis

Johannes Schindelin et al.

NATURE METHODS (2012)

Article Rheumatology

Synovial tissue hypoxia and inflammation in vivo

C. T. Ng et al.

ANNALS OF THE RHEUMATIC DISEASES (2010)

Review Immunology

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

Beatrix Bartok et al.

IMMUNOLOGICAL REVIEWS (2010)

Article Biochemistry & Molecular Biology

Quiescent Fibroblasts Exhibit High Metabolic Activity

Johanna M. S. Lemons et al.

PLOS BIOLOGY (2010)

Article Rheumatology

Predicting the development of RA in patients with early undifferentiated arthritis

Karim Raza et al.

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2009)

Article Endocrinology & Metabolism

A direct cell quenching method for cell-culture based metabolomics

Quincy Teng et al.

METABOLOMICS (2009)

Article Biochemical Research Methods

Optimized metabolite extraction from blood serum for H-1 nuclear magnetic resonance spectroscopy

Stefano Tiziani et al.

ANALYTICAL BIOCHEMISTRY (2008)

Article Rheumatology

Cigarette smoking significantly increases basal metabolic rate in patients with rheumatoid arthritis

G. S. Metsios et al.

ANNALS OF THE RHEUMATIC DISEASES (2008)

Article Rheumatology

Treating very early rheumatoid arthritis

Karim Raza et al.

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2006)

Article Chemistry, Analytical

Targeted profiling:: Quantitative analysis of 1H NMR metabolomics data

Aalim M. Weljie et al.

ANALYTICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Improved methods for the acquisition and interpretation of NMR metabolomic data

MR Viant

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)