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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)
Kinetics of mast cell, basophil, and oral food challenge responses in omalizumab-treated adults with peanut allergy
Jessica H. Savage et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)
Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)
Increased peanut-specific IgA levels in saliva correlate with food challenge outcomes after peanut sublingual immunotherapy
Michael Kulis et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)
Accelerated disassembly of IgE-receptor complexes by a disruptive macromolecular inhibitor
Beomkyu Kim et al.
NATURE (2012)
Mast cell: an emerging partner in immune interaction
Giorgia Gri et al.
FRONTIERS IN IMMUNOLOGY (2012)
Physical interactions between mast cells and eosinophils: a novel mechanism enhancing eosinophil survival in vitro
M. Elishmereni et al.
ALLERGY (2011)
Inhibition of ongoing allergic reactions using a novel anti-IgE DARPin-Fc fusion protein
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ALLERGY (2011)
Omalizumab in Severe Allergic Asthma Inadequately Controlled With Standard Therapy A Randomized Trial
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ANNALS OF INTERNAL MEDICINE (2011)
Efficacy and safety of high-dose peanut oral immunotherapy with factors predicting outcome
K. Anagnostou et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2011)
Mast cells promote Th1 and Th17 responses by modulating dendritic cell maturation and function
Anne Dudeck et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Rapid IgE desensitization is antigen specific and impairs early and late mast cell responses targeting FcεRI internalization
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EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Mast Cells Condition Dendritic Cells to Mediate Allograft Tolerance
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IMMUNITY (2011)
A phase II, randomized, double-blind, parallel-group, placebo-controlled oral food challenge trial of Xolair (omalizumab) in peanut allergy
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2011)
IgE-mediated systemic anaphylaxis and impaired tolerance to food antigens in mice with enhanced IL-4 receptor signaling
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2011)
Sublingual immunotherapy for peanut allergy: Clinical and immunologic evidence of desensitization
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2011)
A randomized controlled study of peanut oral immunotherapy: Clinical desensitization and modulation of the allergic response
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2011)
Reduced Fc epsilon RI-Mediated Release of Asthma-Promoting Cytokines and Chemokines from Human Basophils during Omalizumab Therapy
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INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2010)
Regulation of Syk kinase and FcR beta expression in human basophils during treatment with omalizumab
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)
Oral peanut immunotherapy in children with peanut anaphylaxis
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)
Decreases in human dendritic cell-dependent TH2-like responses after acute in vivo IgE neutralization
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)
Mast Cells, Histamine, and IL-6 Regulate the Selective Influx of Dendritic Cell Subsets into an. Inflamed Lymph Node
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JOURNAL OF IMMUNOLOGY (2010)
IL-33 Is Produced by Mast Cells and Regulates IgE-Dependent Inflammation
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PLOS ONE (2010)
Relationships between Levels of Serum IgE, Cell-Bound IgE, and IgE-Receptors on Peripheral Blood Cells in a Pediatric Population
Eleonora Dehlink et al.
PLOS ONE (2010)
Cell-cell cooperation at the T helper cell/mast cell immunological synapse
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BLOOD (2009)
FcεRI-mediated thymic stromal lymphopoietin production by interleukin-4-primed human mast cells
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EUROPEAN RESPIRATORY JOURNAL (2009)
Omalizumab for the treatment of exacerbations in children with inadequately controlled allergic (IgE-mediated) asthma
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2009)
Inhibition of FcεRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2008)
Allergen skin tests and free IgE levels during reduction and cessation of ornalizumab therapy
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2008)
Suppression of normal and malignant kit signaling by a bispecific antibody linking kit with CD300a
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JOURNAL OF IMMUNOLOGY (2008)
Regulation of the High Affinity IgE Receptor (FcεRI) in Human Neutrophils: Role of Seasonal Allergen Exposure and Th-2 Cytokines
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PLOS ONE (2008)
Immunomodulatory mast cells: negative, as well as positive, regulators of immunity
Stephen J. Galli et al.
NATURE REVIEWS IMMUNOLOGY (2008)
IgE in allergy and asthma today
Hannah J. Gould et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Endocytosis, recycling, and degradation of unoccupied FcεRI in human basophils
Donald W. MacGlashan
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B
Michele A. Grimbaldeston et al.
NATURE IMMUNOLOGY (2007)
Omalizumab reverses the phenotypic and functional effects of IgE-Enhanced FcεRI on human skin mast cells
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JOURNAL OF IMMUNOLOGY (2007)
New developments in FcεRI regulation, function and inhibition
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NATURE REVIEWS IMMUNOLOGY (2007)
Thymic stfomal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells
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JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Safety of anti-immunoglobulin E therapy with omalizumab in allergic patients at risk of geohelminth infection
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CLINICAL AND EXPERIMENTAL ALLERGY (2007)
Egg oral immunotherapy in nonanaphylactic children with egg allergy
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2007)
Proximal signaling events in Fc epsilon RI-mediated mast cell activation
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2007)
Combination treatment with omalizumab and rush immunotherapy for ragweed-induced allergic rhinitis: Inhibition of IgE-facilitated allergen binding
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2007)
IgE-activated mast cells in combination with pro-inflammatory factors induce Th2-promoting dendritic cells
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INTERNATIONAL IMMUNOLOGY (2006)
Dendritic cell modulation by mast cells controls the Th1/Th2 balance in responding T cells
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JOURNAL OF IMMUNOLOGY (2006)
Mast cells are essential intermediaries in regulatory T-cell tolerance
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NATURE (2006)
FcγRIIa, not FcγRIIb, is constitutively and functionally expressed on skin-derived human mast cells
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JOURNAL OF IMMUNOLOGY (2006)
Alteration and acquisition of Siglecs during in vitro maturation of CD34+ progenitors into human mast cells
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ALLERGY (2006)
Mast cell-associated TNF promotes dendritic cell migration
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JOURNAL OF IMMUNOLOGY (2006)
IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and FcγRIIb cross-linking
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JOURNAL OF CLINICAL INVESTIGATION (2006)
Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)
Abrogation of allergic reactions by a bispecific antibody fragment linking IgE to CD300a
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)
Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment):: INNOVATE
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ALLERGY (2005)
The CD200 receptor is a novel and potent regulator of murine and human mast cell function
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JOURNAL OF IMMUNOLOGY (2005)
Efficacy and safety of a recombinant anti-immunoglobulin E antibody (omalizumab) in severe allergic asthma
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CLINICAL AND EXPERIMENTAL ALLERGY (2004)
Omalizumab rapidly decreases nasal allergic response and FcεRI on basophils
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2004)
Omalizumab-induced reductions in mast cell FcεRI expression and function
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2004)
Characterization of FcεRI-bearing CD123+ blood dendritic cell antigen-2+ plasmacytoid dendritic cells in atopic dermatitis
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2004)
Efficacy and tolerability of anti-immunoglobulin E therapy with omalizumab in patients with concomitant allergic asthma and persistent allergic rhinitis: SOLAR
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ALLERGY (2004)
Loss of receptors and IgE in vivo during treatment with anti-IgE antibody
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2004)
Effect of Anti-IgE therapy in patients with peanut allergy
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NEW ENGLAND JOURNAL OF MEDICINE (2003)
Oral desensitizing treatment in food allergy: clinical and immunological results
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ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2003)
Omalizumab treatment downregulates dendritic cell Fc epsilon F-RI expression
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2003)
The crystal structure of IgE Fc reveals an asymmetrically bent conformation
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NATURE IMMUNOLOGY (2002)
A novel human immunoglobulin Fcγ-Fcε bifunctional fusion protein inhibits FcεRI-mediated degranulation
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NATURE MEDICINE (2002)
Detection of novel CD antigens on the surface of human mast cells and basophils
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INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2002)
Histamine polarizes human dendritic cells into Th2 cell-promoting effector dendritic cells
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JOURNAL OF IMMUNOLOGY (2001)
Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2001)
Minimal requirements for IgE-mediated regulation of surface FcεRI
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JOURNAL OF IMMUNOLOGY (2001)
The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics
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EUROPEAN RESPIRATORY JOURNAL (2001)
Mast cells as initiators of immunity and host defense
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EXPERIMENTAL DERMATOLOGY (2001)
IL-4 and-5 prime human mast cells for different profiles of IgE-dependent cytokine production
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The pharmacological basis of anti-IgE therapy
TW Chang
NATURE BIOTECHNOLOGY (2000)
Interleukin-4-induced transcriptional activation by Stat6 involves multiple serine/threonine kinase pathways and serine phosphorylation of Stat6
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BLOOD (2000)