Related references
Note: Only part of the references are listed.Feasibility, long-term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients
Paul N. Harden et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2021)
Tregs and Mixed Chimerism as Approaches for Tolerance Induction in Islet Transplantation
Shiva Pathak et al.
FRONTIERS IN IMMUNOLOGY (2021)
Donor-specific chimeric antigen receptor Tregs limit rejection in naive but not sensitized allograft recipients
Antoine Sicard et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2020)
The Emerging Landscape of Immune Cell Therapies
Evan W. Weber et al.
CELL (2020)
Low-Dose Interleukin-2 Combined With Rapamycin Led to an Expansion of CD4+CD25+FOXP3+Regulatory T Cells and Prolonged Human Islet Allograft Survival in Humanized Mice
Min Hu et al.
DIABETES (2020)
Large-Scale Generation of Human Allospecific Induced Tregs With Functional Stability for Use in Immunotherapy in Transplantation
Evelyn Katy Alvarez-Salazar et al.
FRONTIERS IN IMMUNOLOGY (2020)
Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial
Andy Roemhild et al.
BMJ-BRITISH MEDICAL JOURNAL (2020)
Building a CAR-Treg: Going from the basic to the luxury model
Isaac Rosado-Sanchez et al.
CELLULAR IMMUNOLOGY (2020)
Methods to manufacture regulatory T cells for cell therapy
K. N. MacDonald et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2019)
Next-generation regulatory T cell therapy
Leonardo M. R. Ferreira et al.
NATURE REVIEWS DRUG DISCOVERY (2019)
Low-Dose IL-2 Therapy in Transplantation, Autoimmunity, and Inflammatory Diseases
Maryam Tahvildari et al.
JOURNAL OF IMMUNOLOGY (2019)
IL-2 therapy preferentially expands adoptively transferred donor-specific Tregs improving skin allograft survival
Kulachelvy Ratnasothy et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2019)
Chimeric antigen receptor costimulation domains modulate human regulatory T cell function
Angela C. Boroughs et al.
JCI INSIGHT (2019)
Mixed chimerism established by hematopoietic stem cell transplantation is maintained by host and donor T regulatory cells
Francesca A. M. Kinsella et al.
BLOOD ADVANCES (2019)
Chimeric Antigen Receptor Therapy
Carl H. June et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
A Phase I Clinical Trial with Ex Vivo Expanded Recipient Regulatory T cells in Living Donor Kidney Transplants
James M. Mathew et al.
SCIENTIFIC REPORTS (2018)
Chimeric Antigen Receptor Expressing Natural Killer Cells for the Immunotherapy of Cancer
Rohtesh S. Mehta et al.
FRONTIERS IN IMMUNOLOGY (2018)
Equal Expansion of Endogenous Transplant-Specific Regulatory T Cell and Recruitment Into the Allograft During Rejection and Tolerance
James S. Young et al.
FRONTIERS IN IMMUNOLOGY (2018)
Generation and Characterization of Alloantigen-Specific Regulatory T Cells For Clinical Transplant Tolerance
James M. Mathew et al.
SCIENTIFIC REPORTS (2018)
The Biology of T Regulatory Type 1 Cells and Their Therapeutic Application in Immune-Mediated Diseases
Maria Grazia Roncarolo et al.
IMMUNITY (2018)
Treg cells-the next frontier of cell therapy Will regulatory T cells be a frontline therapy for autoimmunity and other diseases?
Jeffrey A. Bluestone et al.
SCIENCE (2018)
Revisiting IL-2: Biology and therapeutic prospects
Abul K. Abbas et al.
SCIENCE IMMUNOLOGY (2018)
Early expansion of donor-specific Tregs in tolerant kidney transplant recipients
Thomas M. Savage et al.
JCI INSIGHT (2018)
Development of T-cell immunotherapy for hematopoietic stem cell transplantation recipients at risk of leukemia relapse
Robson G. Dossa et al.
BLOOD (2018)
Generation of donor-specific Tr1 cells to be used after kidney transplantation and definition of the timing of their in vivo infusion in the presence of immunosuppression
Bechara Mfarrej et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2017)
Mechanisms of Mixed Chimerism-Based Transplant Tolerance
Julien Zuber et al.
TRENDS IN IMMUNOLOGY (2017)
Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants
S. Chandran et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2017)
Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection
D. A. Boardman et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2017)
Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC-Specific Chimeric Antigen Receptor
F. Noyan et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2017)
Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease
James B. Canavan et al.
GUT (2016)
Selective CD28 Antagonist Blunts Memory Immune Responses and Promotes Long-Term Control of Skin Inflammation in Nonhuman Primates
Nicolas Poirier et al.
JOURNAL OF IMMUNOLOGY (2016)
Ex Vivo Costimulatory Blockade to Generate Regulatory T Cells From Patients Awaiting Kidney Transplantation
E. C. Guinan et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2016)
Costimulation Blockade in Autoimmunity and Transplantation: The CD28 Pathway
Andrew B. Adams et al.
JOURNAL OF IMMUNOLOGY (2016)
Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus
Jing He et al.
NATURE MEDICINE (2016)
Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation
Niloufar Safinia et al.
ONCOTARGET (2016)
Comparative Analysis of Protocols to Induce Human CD4+Foxp3+Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate
Angelika Schmidt et al.
PLOS ONE (2016)
Regulatory T cell memory
Michael D. Rosenblum et al.
NATURE REVIEWS IMMUNOLOGY (2016)
Induced regulatory T cells in allograft tolerance via transient mixed chimerism
Kiyohiko Hotta et al.
JCI INSIGHT (2016)
IL-17 Deficiency Attenuates Allograft Injury and Prolongs Survival in a Murine Model of Fully MHC-Mismatched Renal Allograft Transplantation
T. Kwan et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2015)
Blockade of CD40-CD154 Costimulatory Pathway Promotes Long-Term Survival of Full-Thickness Porcine Corneal Grafts in Nonhuman Primates: Clinically Applicable Xenocorneal Transplantation
H. J. Choi et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2015)
Targeting Treg signaling for the treatment of autoimmune diseases
Allyson Spence et al.
CURRENT OPINION IN IMMUNOLOGY (2015)
Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients
Michelle Rosenzwajg et al.
JOURNAL OF AUTOIMMUNITY (2015)
Methyl-Guanine-Methyl-Transferase Transgenic Bone Marrow Transplantation Allows N,N-bis (2-chloroethyl)-Nitrosourea Driven Donor Mixed-Chimerism Without Graft-Versus-Host Disease, and With Donor-Specific Allograft Tolerance
Min Hu et al.
TRANSPLANTATION (2015)
Ex Vivo-Expanded but Not In Vitro-Induced Human Regulatory T Cells Are Candidates for Cell Therapy in Autoimmune Diseases Thanks to Stable Demethylation of the FOXP3 Regulatory T Cell-Specific Demethylated Region
Maura Rossetti et al.
JOURNAL OF IMMUNOLOGY (2015)
Attenuation of Donor-Reactive T Cells Allows Effective Control of Allograft Rejection Using Regulatory T Cell Therapy
K. Lee et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2014)
Administration of Low Doses of IL-2 Combined to Rapamycin Promotes Allogeneic Skin Graft Survival in Mice
C. B. Pilon et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2014)
Pathogenic conversion of Foxp3(+) T cells into T(H)17 cells in autoimmune arthritis
Noriko Komatsu et al.
NATURE MEDICINE (2014)
Infiltrating Foxp3+ Regulatory T Cells From Spontaneously Tolerant Kidney Allografts Demonstrate Donor-Specific Tolerance
M. Hu et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2013)
Clinical Grade Manufacturing of Human Alloantigen-Reactive Regulatory T Cells for Use in Transplantation
A. L. Putnam et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2013)
The life of regulatory T cells
Iris K. Gratz et al.
TRANSLATIONAL IMMUNOLOGY IN ASIA-OCEANIA (2013)
Promoting regulation via the inhibition of DNAM-1 after transplantation
Motoko Koyama et al.
BLOOD (2013)
Foxp3+ regulatory T cells are activated in spite of B7-CD28 and CD40-CD40L blockade
Isabel Vogel et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Regulatory T cells: recommendations to simplify the nomenclature
Abul K. Abbas et al.
NATURE IMMUNOLOGY (2013)
HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression
Tatsuo Kawai et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Gene-engineered T cells for cancer therapy
Michael H. Kershaw et al.
NATURE REVIEWS CANCER (2013)
Fates of CD4+T Cells in a Tolerant Environment Depend on Timing and Place of Antigen Exposure
B. E. Burrell et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2012)
Low-Dose Rapamycin Treatment Increases the Ability of Human Regulatory T Cells to Inhibit Transplant Arteriosclerosis In Vivo
J. Hester et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2012)
CTLA4-Ig Restores Rejection of MHC Class-II Mismatched Allografts by Disabling IL-2-Expanded Regulatory T Cells
L. -M. Charbonnier et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2012)
Deleterious Effect of CTLA4-Ig on a Treg-Dependent Transplant Model
L. V. Riella et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2012)
Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice
Shounan Yi et al.
DIABETES (2012)
Chimerism and Tolerance Without GVHD or Engraftment Syndrome in HLA-Mismatched Combined Kidney and Hematopoietic Stem Cell Transplantation
Joseph Leventhal et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
The role of interleukin-2 during homeostasis and activation of the immune system
Onur Boyman et al.
NATURE REVIEWS IMMUNOLOGY (2012)
Early Acceptance of Renal Allografts in Mice Is Dependent on Foxp3+ Cells
Masahiro Miyajima et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Regulatory T Cells Require Mammalian Target of Rapamycin Signaling To Maintain Both Homeostasis and Alloantigen-Driven Proliferation in Lymphocyte-Replete Mice
Ying Wang et al.
JOURNAL OF IMMUNOLOGY (2011)
Response to self antigen imprints regulatory memory in tissues
Michael D. Rosenblum et al.
NATURE (2011)
The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
Erika Cretney et al.
NATURE IMMUNOLOGY (2011)
Regulatory T-Cell Responses to Low-Dose Interleukin-2 in HCV-Induced Vasculitis
David Saadoun et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease
John Koreth et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Human Regulatory T Cells with Alloantigen Specificity Are More Potent Inhibitors of Alloimmune Skin Graft Damage than Polyclonal Regulatory T Cells
Pervinder Sagoo et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Cardiac allograft acceptance induced by blockade of CD40-CD40L costimulation is dependent on CD4+CD25+ regulatory T cells
Xiaofeng Jiang et al.
SURGERY (2011)
Spontaneous acceptance of mouse kidney allografts is associated with increased Foxp3 expression and differences in the B and T cell compartments
Chuanmin Wang et al.
TRANSPLANT IMMUNOLOGY (2011)
The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor
Michael Hudecek et al.
BLOOD (2010)
Mechanistic and therapeutic role of regulatory T cells in tolerance through mixed chimerism
Nina Pilat et al.
CURRENT OPINION IN ORGAN TRANSPLANTATION (2010)
Mechanisms of Disease: Rejection of the Kidney Allograft.
Brian J. Nankivell et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
CD4+CD25+ T cells alloactivated ex vivo by IL-2 or IL-4 become potent alloantigen-specific inhibitors of rejection with different phenotypes, suggesting separate pathways of activation by Th1 and Th2 responses
Nirupama D. Verma et al.
BLOOD (2009)
In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression
Kylie E. Webster et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Efficient Induction and Expansion of Human Alloantigen-Specific CD8 Regulatory T Cells from Naive Precursors by CD40-Activated B Cells
Jian Zheng et al.
JOURNAL OF IMMUNOLOGY (2009)
HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide
Leo Luznik et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2008)
T Regulatory Cells in Autoimmune Diabetes: Past Challenges, Future Prospects
Jeffrey A. Bluestone et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2008)
In vitro expansion improves in vivo regulation by CD4+CD25+ regulatory T cells
Jian-Guo Chai et al.
JOURNAL OF IMMUNOLOGY (2008)
Brief report: Chimerism and tolerance in a recipient of a deceased-donor liver transplant
Stephen I. Alexander et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Brief report: HLA-mismatched renal transplantation without maintenance immunosuppression
Tatsuo Kawai et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Brief report: Tolerance and chimerism after renal and hematopoietic-cell transplantation
John D. Scandling et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Ex Vivo Generation of Human Alloantigen-Specific Regulatory T Cells from CD4posCD25high T Cells for Immunotherapy
Jorieke H. Peters et al.
PLOS ONE (2008)
Induction of antigen-specific regulatory T cells in wild-type mice: Visualization and targets of suppression
Panayotis Verginis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Prevention of acute and chronic allograft rejection with CD4(+)CD25(+)Foxp3(+) regulatory T lymphocytes
Olivier Joffre et al.
NATURE MEDICINE (2008)
In-vitro generation and characterisation of murine CD4+CD25+ regulatory T cells with indirect allospecificity
Julia Tsang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2006)
Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients
Manuela Battaglia et al.
JOURNAL OF IMMUNOLOGY (2006)
Recipient memory-like lymphocytes remain unresponsive to graft antigens after CAMPATH-1H induction with reduced maintenance immunosuppression
Piotr Trzonkowski et al.
TRANSPLANTATION (2006)
Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts
Jordi C. Ochando et al.
NATURE IMMUNOLOGY (2006)
Antigen-induced IL-10+ regulatory T cells are independent of CD25+ regulatory cells for their growth, differentiation, and function
Kirsty S. Nicolson et al.
JOURNAL OF IMMUNOLOGY (2006)
Antigen-specific regulatory T cells - Ex vivo expansion and therapeutic potential
EL Masteller et al.
SEMINARS IN IMMUNOLOGY (2006)
Requirements for induction and maintenance of peripheral tolerance in stringent allograft models
M Sho et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: The interplay of clonal anergy and immune regulation
SA Quezada et al.
JOURNAL OF IMMUNOLOGY (2005)
Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells
M Battaglia et al.
BLOOD (2005)
The role of non-deletional tolerance mechanisms in a murine model of mixed chimerism with costimulation blockade
S Bigenzahn et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2005)
Organ transplantation - how much of the promise has been realized?
RI Lechler et al.
NATURE MEDICINE (2005)
Donor-specific transplantation tolerance:: The paradoxical behavior of CD4+CD25+ T cells
L Graca et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
QZ Tang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Transplantation tolerance induced by intranasal administration of HY peptides
JG Chai et al.
BLOOD (2004)
Control of regulatory T cell development by the transcription factor Foxp3
S Hori et al.
SCIENCE (2003)
CD25+CD4+ regulatory T cells prevent graft rejection:: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
CI Kingsley et al.
JOURNAL OF IMMUNOLOGY (2002)
Murine renal allografts: Spontaneous acceptance is associated with regulated T cell-mediated immunity
AA Bickerstaff et al.
JOURNAL OF IMMUNOLOGY (2001)
CD4+CD25+ immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade
PA Taylor et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
The importance of H2 haplotype sharing in the induction of specific unresponsiveness by pretransplant blood transfusions
M Niimi et al.
TRANSPLANTATION (2000)