4.8 Article

Trained Immunity Confers Prolonged Protection From Listeriosis

Related references

Note: Only part of the references are listed.
Review Immunology

The Intersection of Epigenetics and Metabolism in Trained Immunity

Stephanie Fanucchi et al.

Summary: Recent research has shown that innate immune cells can also exhibit immune memory characteristics, termed trained immunity. Trained immunity is involved in infections, vaccination, and inflammatory diseases, and is based on the epigenetic and metabolic reprogramming of cells.

IMMUNITY (2021)

Editorial Material Immunology

Trained immunity, tolerance, priming and differentiation: distinct immunological processes

Maziar Divangahi et al.

Summary: Researchers are working towards establishing a set of experimental standards to reach consensus on defining trained immunity, which will help advance research in this field.

NATURE IMMUNOLOGY (2021)

Article Biochemistry & Molecular Biology

Macrophage migration inhibitory factor promotes the migration of dendritic cells through CD74 and the activation of the Src/PI3K/myosin II pathway

Annette Ives et al.

Summary: The cytokine MIF plays a chemokine-like role in promoting the migration of dendritic cells (DCs) by activating the Src/PI3K signaling pathway and myosin II complexes. MIF contributes to the recruitment of DCs to draining lymph nodes through autocrine and paracrine activities acting via CD74. These findings indicate that MIF is crucial for DC motility and trafficking.

FASEB JOURNAL (2021)

Article Immunology

The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma

Mukesh Verma et al.

Summary: Repetitive exposure of Rag1(-/-) mice to the Alternaria allergen extract generated a memory effect associated with lung ILC2s, leading to an asthma-like response. Memory ILC2s display a distinct epigenetic landscape, driven by altered gene accessibility factors, such as Bach2 and AP1 motifs.

JOURNAL OF EXPERIMENTAL MEDICINE (2021)

Article Immunology

Human Newborn Monocytes Demonstrate Distinct BCG-Induced Primary and Trained Innate Cytokine Production and Metabolic Activation In Vitro

Asimenia Angelidou et al.

Summary: The study revealed significant differences in immune responses to BCG vaccine between neonatal and adult monocytes, including primary and memory cytokine responses and immunometabolic shifts. Neonatal monocytes exhibited enhanced production of certain cytokines and showed tolerization upon subsequent LPS stimulation, contrasting with adult monocytes.

FRONTIERS IN IMMUNOLOGY (2021)

Article Immunology

Trained Immunity Confers Broad-Spectrum Protection Against Bacterial Infections

Eleonora Ciarlo et al.

JOURNAL OF INFECTIOUS DISEASES (2020)

Review Cell Biology

Mitochondrial Functions in Infection and Immunity

Varnesh Tiku et al.

TRENDS IN CELL BIOLOGY (2020)

Article Cell & Tissue Engineering

C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells

Berengere de Laval et al.

CELL STEM CELL (2020)

Article Cell Biology

BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis

Byron Brook et al.

SCIENCE TRANSLATIONAL MEDICINE (2020)

Article Medicine, Research & Experimental

Lung group 2 innate lymphoid cells are trained by endogenous IL-33 in the neonatal period

Catherine A. Steer et al.

JCI INSIGHT (2020)

Review Infectious Diseases

Vaccinology: time to change the paradigm?

Christine Stabell Benn et al.

LANCET INFECTIOUS DISEASES (2020)

Article Cell Biology

BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils

Simone J. C. F. M. Moorlag et al.

CELL REPORTS (2020)

Review Immunology

Overcoming immune dysfunction in the elderly: trained immunity as a novel approach

Ozlem Bulut et al.

INTERNATIONAL IMMUNOLOGY (2020)

Article Biochemistry & Molecular Biology

Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity

Lydia Kalafati et al.

Review Immunology

Defining trained immunity and its role in health and disease

Mihai G. Netea et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Article Multidisciplinary Sciences

Outcomes of controlled human malaria infection after BCG vaccination

Jona Walk et al.

NATURE COMMUNICATIONS (2019)

Article Biotechnology & Applied Microbiology

Therapeutic targeting of trained immunity

Willem J. M. Mulder et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

Article Public, Environmental & Occupational Health

BCG vaccination is associated with reduced malaria prevalence in children under the age of 5 years in sub-Saharan Africa

Mike L. T. Berendsen et al.

BMJ GLOBAL HEALTH (2019)

Review Immunology

The role of the interleukin-1 family in trained immunity

Simone J. C. F. M. Moorlag et al.

IMMUNOLOGICAL REVIEWS (2018)

Article Biochemistry & Molecular Biology

Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming

Anette Christ et al.

Article Biochemistry & Molecular Biology

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

Ioannis Mitroulis et al.

Article Biochemistry & Molecular Biology

Metabolic Induction of Trained Immunity through the Mevalonate Pathway

Siroon Bekkering et al.

Article Microbiology

The Case for an Expanded Concept of Trained Immunity

Antonio Cassone

Article Multidisciplinary Sciences

Allergic inflammatory memory in human respiratory epithelial progenitor cells

Jose Ordovas-Montanes et al.

NATURE (2018)

Article Multidisciplinary Sciences

Innate immune memory in the brain shapes neurological disease hallmarks

Ann-Christin Wendeln et al.

NATURE (2018)

Article Multidisciplinary Sciences

Interferon stimulation creates chromatin marks and establishes transcriptional memory

Rui Kamada et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Immunology

Sirtuin 5 Deficiency Does Not Compromise Innate Immune Responses to Bacterial Infections

Tytti Heinonen et al.

FRONTIERS IN IMMUNOLOGY (2018)

Review Cell Biology

Hypothesis: stimulation of trained immunity as adjunctive immunotherapy in cancer

Mihai G. Netea et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2017)

Article Multidisciplinary Sciences

Inflammatory memory sensitizes skin epithelial stem cells to tissue damage

Shruti Naik et al.

NATURE (2017)

Article Multidisciplinary Sciences

Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections

Eleonora Ciarlo et al.

SCIENTIFIC REPORTS (2017)

Review Immunology

Immunometabolism governs dendritic cell and macrophage function

Luke A. J. O'Neill et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2016)

Article Cell Biology

Immunometabolic Pathways in BCG-Induced Trained Immunity

Rob J. W. Arts et al.

CELL REPORTS (2016)

Article Immunology

Immunological memory: lessons from the past and a look to the future

Donna L. Farber et al.

NATURE REVIEWS IMMUNOLOGY (2016)

Review Immunology

Natural killer cell memory in infection, inflammation and cancer

Adelheid Cerwenka et al.

NATURE REVIEWS IMMUNOLOGY (2016)

Article Immunology

Long-Lasting Effects of BCG Vaccination on Both Heterologous Th1/Th17 Responses and Innate Trained Immunity

Johanneke Kleinnijenhuis et al.

JOURNAL OF INNATE IMMUNITY (2014)

Article Multidisciplinary Sciences

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity

Shih-Chin Cheng et al.

SCIENCE (2014)

Article Immunology

Candida albicans Primes TLR Cytokine Responses through a Dectin-1/Raf-1-Mediated Pathway

Daniela C. Ifrim et al.

JOURNAL OF IMMUNOLOGY (2013)

Article Multidisciplinary Sciences

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

Johanneke Kleinnijenhuis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Microbiology

Trained Immunity: A Memory for Innate Host Defense

Mihai G. Netea et al.

CELL HOST & MICROBE (2011)