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MHC class I chain-related protein A and B (MICA and MICB) are predominantly expressed intracellularly in tumour and normal tissue
Hormas Ghadially et al.
BRITISH JOURNAL OF CANCER (2017)
Targeting NK-cell checkpoints for cancer immunotherapy
Aura Muntasell et al.
CURRENT OPINION IN IMMUNOLOGY (2017)
Immunogenic cell death in cancer and infectious disease
Lorenzo Galluzzi et al.
NATURE REVIEWS IMMUNOLOGY (2017)
Clinical significance of tumor expression of major histocompatibility complex class I-related chains A and B (MICA/B) in gastric cancer patients
Carolina Hager Ribeiro et al.
ONCOLOGY REPORTS (2016)
The clinical and biological significance of MICA in clear cell renal cell carcinoma patients
Xiang Zhang et al.
TUMOR BIOLOGY (2016)
Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model
David A. Reardon et al.
CANCER IMMUNOLOGY RESEARCH (2016)
Antibody targeting soluble NKG2D ligand sMIC refuels and invigorates the endogenous immune system to fight cancer
Jennifer Wu
ONCOIMMUNOLOGY (2016)
ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing
Maria Raffaella Zocchi et al.
ONCOIMMUNOLOGY (2016)
MHC class I chain-related molecule A and B expression is upregulated by cisplatin and associated with good prognosis in patients with non-small cell lung cancer
Riki Okita et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2016)
Overexpression of natural killer group 2 member D ligands predicts favorable prognosis in cholangiocarcinoma
Mariko Tsukagoshi et al.
CANCER SCIENCE (2016)
MICA*A4 protects against ulcerative colitis, whereas MICA*A5.1 is associated with abscess formation and age of onset
A. Martinez-Chamorro et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2016)
Checkpoint Inhibition of KIR2D with the Monoclonal Antibody IPH2101 Induces Contraction and Hyporesponsiveness of NK Cells in Patients with Myeloma
Mattias Carlsten et al.
CLINICAL CANCER RESEARCH (2016)
Targeting NKG2D and NKp30 Ligands Shedding to Improve NK Cell-Based Immunotherapy
Alessandra Zingoni et al.
CRITICAL REVIEWS IN IMMUNOLOGY (2016)
Discovery of a new selective inhibitor of A Disintegrin And Metalloprotease 10 (ADAM-10) able to reduce the shedding of NKG2D ligands in Hodgkin's lymphoma cell models
Caterina Camodeca et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility
Kensuke Shiraishi et al.
JOURNAL OF GASTROENTEROLOGY (2016)
Targeting natural killer cells in cancer immunotherapy
Camille Guillerey et al.
NATURE IMMUNOLOGY (2016)
Development of immuno-oncology drugs - from CTLA4 to PD1 to the next generations
Axel Hoos
NATURE REVIEWS DRUG DISCOVERY (2016)
TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
Sebastien Viel et al.
SCIENCE SIGNALING (2016)
SEP enhanced the antitumor activity of 5-fluorouracil by up-regulating NKG2D/MICA and reversed immune suppression via inhibiting ROS and caspase-3 in mice
Mengyun Ke et al.
ONCOTARGET (2016)
TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
Sebastien Viel et al.
SCIENCE SIGNALING (2016)
Synergistic COX2 Induction by IFNγ and TNFα Self-Limits Type-1 Immunity in the Human Tumor Microenvironment
Jeffrey L. Wong et al.
CANCER IMMUNOLOGY RESEARCH (2016)
Impact of the MICA-129Met/Val Dimorphism on NKG2D-Mediated Biological Functions and Disease Risks
Antje Isernhagen et al.
FRONTIERS IN IMMUNOLOGY (2016)
NK cells and cancer: you can teach innate cells new tricks
Maelig G. Morvan et al.
NATURE REVIEWS CANCER (2016)
TAM Receptor Signaling in Immune Homeostasis
Carla V. Rothlin et al.
ANNUAL REVIEW OF IMMUNOLOGY VOL 33 (2015)
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
Padmanee Sharma et al.
CELL (2015)
Nonblocking Monoclonal Antibody Targeting Soluble MIC Revamps Endogenous Innate and Adaptive Antitumor Responses and Eliminates Primary and Metastatic Tumors
Shengjun Lu et al.
CLINICAL CANCER RESEARCH (2015)
Oxaliplatin regulates expression of stress ligands in ovarian cancer cells and modulates their susceptibility to natural killer cell-mediated cytotoxicity
Yin-Yin Siew et al.
INTERNATIONAL IMMUNOLOGY (2015)
Big opportunities for small molecules in immuno-oncology
Jerry L. Adams et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade
Juan Fu et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
Leticia Corrales et al.
CELL REPORTS (2015)
NKG2D Receptor and Its Ligands in Host Defense
Lewis L. Lanier
CANCER IMMUNOLOGY RESEARCH (2015)
NKG2D ligands in tumor immunity: two sides of a coin
Jinyu Zhang et al.
FRONTIERS IN IMMUNOLOGY (2015)
IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness
Andrea Ziblat et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2015)
Acute Antibody-Mediated Rejection in Presence of MICA-DSA and Successful Renal Re-Transplant with Negative-MICA Virtual Crossmatch
Yingzi Ming et al.
PLOS ONE (2015)
MICA, a gene contributing strong susceptibility to ankylosing spondylitis
Xiaodong Zhou et al.
ANNALS OF THE RHEUMATIC DISEASES (2014)
Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies
Holbrook E. Kohrt et al.
BLOOD (2014)
c-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis
Arash Nanbakhsh et al.
BLOOD (2014)
Valproic acid sensitizes pancreatic cancer cells to natural killer cell-mediated lysis by upregulating MICA and MICB via the PI3K/Akt signaling pathway
Pengfei Shi et al.
BMC CANCER (2014)
Metastatic Consequences of Immune Escape from NK Cell Cytotoxicity by Human Breast Cancer Stem Cells
Bin Wang et al.
CANCER RESEARCH (2014)
RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Adeline R. Lam et al.
CANCER RESEARCH (2014)
Inhibition of Tumor-Derived Prostaglandin-E2 Blocks the Induction of Myeloid-Derived Suppressor Cells and Recovers Natural Killer Cell Activity
Yumeng Mao et al.
CLINICAL CANCER RESEARCH (2014)
A phase II trial of pan-KIR2D blockade with IPH2101 in smoldering multiple myeloma
Neha Korde et al.
HAEMATOLOGICA (2014)
STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
Seng-Ryong Woo et al.
IMMUNITY (2014)
Natural cytotoxicity receptors and their ligands
Philip H. Kruse et al.
IMMUNOLOGY AND CELL BIOLOGY (2014)
NK-cell dysfunction in human renal carcinoma reveals diacylglycerol kinase as key regulator and target for therapeutic intervention
Petra U. Prinz et al.
INTERNATIONAL JOURNAL OF CANCER (2014)
Expression of major histocompatibility complex class I-related chain A/B (MICA/B) in pancreatic carcinoma
Zilvinas Dambrauskas et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
N-Glycosylation of Asparagine 8 Regulates Surface Expression of Major Histocompatibility Complex Class I Chain-related Protein A (MICA) Alleles Dependent on Threonine 24
Maiken Mellergaard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
MICA/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma
Liang Fang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2014)
The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions
Christopher J. Chan et al.
NATURE IMMUNOLOGY (2014)
DMXAA Causes Tumor Site-Specific Vascular Disruption in Murine Non-Small Cell Lung Cancer, and like the Endogenous Non-Canonical Cyclic Dinucleotide STING Agonist, 2′3′-cGAMP, Induces M2 Macrophage Repolarization
Charlene M. Downey et al.
PLOS ONE (2014)
TGF-β-inducible microRNA-183 silences tumor-associated natural killer cells
Sarah S. Donatelli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells
Priyanka Sathe et al.
NATURE COMMUNICATIONS (2014)
A GPI anchor explains the unique biological features of the common NKG2D-ligand allele MICA*008
Omodele Ashiru et al.
BIOCHEMICAL JOURNAL (2013)
Expansion of CD11b+Ly6G+Ly6Cint cells driven by medroxyprogesterone acetate in mice bearing breast tumors restrains NK cell effector functions
Raul German Spallanzani et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2013)
Potential for enhanced therapeutic activity of biological cancer therapies with doxycycline combination
H. Tang et al.
GENE THERAPY (2013)
NKG2D CAR T-cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors
Paul Spear et al.
IMMUNOLOGY AND CELL BIOLOGY (2013)
Shedding of endogenous MHC class I-related chain molecules A and B from different human tumor entities: Heterogeneous involvement of the a disintegrin and metalloproteases 10 and 17
Guranda Chitadze et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Perturbation of NK cell peripheral homeostasis accelerates prostate carcinoma metastasis
Gang Liu et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Sensitizing primary acute lymphoblastic leukemia to natural killer cell recognition by induction of NKG2D ligands
Laura Jardine et al.
LEUKEMIA & LYMPHOMA (2013)
Type I interferon response and innate immune sensing of cancer
Mercedes B. Fuertes et al.
TRENDS IN IMMUNOLOGY (2013)
A prostaglandin E (PGE) receptor EP4 antagonist protects natural killer cells from PGE2-mediated immunosuppression and inhibits breast cancer metastasis
Xinrong Ma et al.
ONCOIMMUNOLOGY (2013)
Modulation of Host Natural Killer Cell Functions in Breast Cancer via Prostaglandin E2 Receptors EP2 and EP4
Dawn M. Holt et al.
JOURNAL OF IMMUNOTHERAPY (2012)
Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression
Lucas E. Rossi et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2012)
Human NKG23-ligands: cell biology strategies to ensure immune recognition
Lola Fernandez-Messina et al.
FRONTIERS IN IMMUNOLOGY (2012)
Valproic Acid Upregulates NKG2D Ligand Expression through an ERK-dependent Mechanism and Potentially Enhances NK Cell-mediated Lysis of Myeloma
Xiaosong Wu et al.
NEOPLASIA (2012)
Histone deacetylase inhibitors enhance expression of NKG2D ligands in Ewing sarcoma and sensitize for natural killer cell-mediated cytolysis
Dagmar Berghuis et al.
CLINICAL SARCOMA RESEARCH (2012)
Inflammation restraining effects of prostaglandin E2 on natural killer-dendritic cell (NK-DC) interaction are imprinted during DC maturation
Catharina H. M. J. Van Elssen et al.
BLOOD (2011)
Successful transfer of alloreactive haploidentical KIR ligand-mismatched natural killer cells after infusion in elderly high risk acute myeloid leukemia patients
Antonio Curti et al.
BLOOD (2011)
IPH2101, a novel anti-inhibitory KIR antibody, and lenalidomide combine to enhance the natural killer cell versus multiple myeloma effect
Don M. Benson et al.
BLOOD (2011)
Prostaglandin E2 (PGE2) suppresses natural killer cell function primarily through the PGE2 receptor EP4
Dawn Holt et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2011)
COX-2 Blockade Suppresses Gliomagenesis by Inhibiting Myeloid-Derived Suppressor Cells
Mitsugu Fujita et al.
CANCER RESEARCH (2011)
Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma
Yoshihiro Komohara et al.
CANCER SCIENCE (2011)
MMP9 mediates MICA shedding in human osteosarcomas
Dahui Sun et al.
CELL BIOLOGY INTERNATIONAL (2011)
Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor Regression
Maria R. Parkhurst et al.
CLINICAL CANCER RESEARCH (2011)
Role of sorafenib and sunitinib in the induction of expressions of NKG2D ligands in nasopharyngeal carcinoma with high expression of ABCG2
Yuxian Huang et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2011)
Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells
Mercedes B. Fuertes et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Modulation of NKG2D-ligand Cell Surface Expression Enhances Immune Cell Therapy of Cancer
Baocheng Huang et al.
JOURNAL OF IMMUNOTHERAPY (2011)
HLA and MICA: Targets of Antibody-Mediated Rejection in Heart Transplantation
Qiuheng Zhang et al.
TRANSPLANTATION (2011)
Natural Killer Cell Cytotoxicity Is Suppressed by Exposure to the Human NKG2D Ligand MICA*008 That Is Shed by Tumor Cells in Exosomes
Omodele Ashiru et al.
CANCER RESEARCH (2010)
Hydroxyurea upregulates NKG2D ligand expression in myeloid leukemia cells synergistically with valproic acid and potentially enhances susceptibility of leukemic cells to natural killer cell-mediated cytolysis
Xuzhang Lu et al.
CANCER SCIENCE (2010)
Immunogenic Tumor Cell Death for Optimal Anticancer Therapy: The Calreticulin Exposure Pathway
Laurence Zitvogel et al.
CLINICAL CANCER RESEARCH (2010)
Association analysis of MICA gene polymorphism and MICA-129 dimorphism with inflammatory bowel disease susceptibility in a Spanish population
Ruth Lopez-Hernandez et al.
HUMAN IMMUNOLOGY (2010)
ULBP2 and RAET1E NKG2D ligands are independent predictors of poor prognosis in ovarian cancer patients
Roger W. McGilvray et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Post-translational Modification of the NKG2D Ligand RAET1G Leads to Cell Surface Expression of a Glycosylphosphatidylinositol-linked Isoform
Maki Ohashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Differential Mechanisms of Shedding of the Glycosylphosphatidylinositol (GPI)-anchored NKG2D Ligands
Lola Fernandez-Messina et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
NKAML: A Pilot Study to Determine the Safety and Feasibility of Haploidentical Natural Killer Cell Transplantation in Childhood Acute Myeloid Leukemia
Jeffrey E. Rubnitz et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Cutting Edge: The Membrane Type Matrix Metalloproteinase MMP14 Mediates Constitutive Shedding of MHC Class I Chain-Related Molecule A Independent of A Disintegrin and Metalloproteinases
Gang Liu et al.
JOURNAL OF IMMUNOLOGY (2010)
Induction of a less aggressive phenotype in human colon carcinoma HCT116 cells by chronic exposure to HDAC inhibitor SAHA
Alessandro Bressan et al.
ONCOLOGY REPORTS (2010)
Sodium valproate, a histone deacetylase inhibitor, augments the expression of cell-surface NKG2D ligands, MICA/B, without increasing their soluble forms to enhance susceptibility of human osteosarcoma cells to NK cell-mediated cytotoxicity
Koji Yamanegi et al.
ONCOLOGY REPORTS (2010)
ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype
Alessandra Soriani et al.
BLOOD (2009)
Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells
Francois Romagne et al.
BLOOD (2009)
Sodium butyrate upregulates expression of NKG2D ligand MICA/B in HeLa and HepG2 cell lines and increases their susceptibility to NK lysis
Cai Zhang et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2009)
NKG2D Ligand Expression in Human Colorectal Cancer Reveals Associations with Prognosis and Evidence for Immunoediting
Roger W. McGilvray et al.
CLINICAL CANCER RESEARCH (2009)
Obstructing Shedding of the Immunostimulatory MHC Class I Chain-Related Gene B Prevents Tumor Formation
Jennifer D. Wu et al.
CLINICAL CANCER RESEARCH (2009)
ULBP6/RAET1L is an additional human NKG2D ligand
Robert A. Eagle et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
Cutting Edge: The Metalloproteinase ADAM17/TNF-α-Converting Enzyme Regulates Proteolytic Shedding of the MHC Class I-Related Chain B Protein
Philippe Boutet et al.
JOURNAL OF IMMUNOLOGY (2009)
Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF-beta 1
Hequan Li et al.
JOURNAL OF IMMUNOLOGY (2009)
NKG2D Ligands Expression and NKG2D-Mediated NK Activity in Sezary Patients
Nicolas Dulphy et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2009)
Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproate
A. Poggi et al.
LEUKEMIA (2009)
Defective Infiltration of Natural Killer Cells in MICA/B-Positive Renal Cell Carcinoma Involves β2-Integrin-Mediated Interaction
Guiseppe Sconocchia et al.
NEOPLASIA (2009)
Histone deacetylase inhibitors sensitize tumour cells for cytotoxic effects of natural killer cells
Mareike Schmudde et al.
CANCER LETTERS (2008)
Selective induction of expression of a ligand for the NKG2D receptor by proteasome inhibitors
Mar Vales-Gomez et al.
CANCER RESEARCH (2008)
Tumor-associated MICA is shed by ADAM proteases
Inja Waldhauer et al.
CANCER RESEARCH (2008)
Direct and natural killer cell-mediated antitumor effects of low-dose Bortezomib in hepatocellular carcinoma
Sorin Armeanu et al.
CLINICAL CANCER RESEARCH (2008)
NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy
Nadia Guerra et al.
IMMUNITY (2008)
Potentiation of NK cell-mediated cytotoxicity in human lung adenocarcinoma: role of NKG2D-dependent pathway
Beatrice Le Maux Chansac et al.
INTERNATIONAL IMMUNOLOGY (2008)
Intracellular retention of the NKG2D ligand MHC class I chain-related gene a in human melanomas confers immune privilege and prevents NK cell-mediated cytotoxicity
Mercedes B. Fuertes et al.
JOURNAL OF IMMUNOLOGY (2008)
TGF-β utilizes SMAD3 to inhibit CD16-mediated IFN-γ production and antibody-dependent cellular cytotoxicity in human NK cells
Rossana Trotta et al.
JOURNAL OF IMMUNOLOGY (2008)
MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma
Masahisa Jinushi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificities
Stefan Diermayr et al.
BLOOD (2008)
Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells
N. Kato et al.
LEUKEMIA (2007)
Antibodies against MICA antigens and kidney-transplant rejection
Yizhou Zou et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Engagement of TLR3, TLR7, and NKG2D regulate IFN-γ secretion but not NKG2D-Mediated cytotoxicity by human NK cells stimulated with suboptimal doses of IL-12
Maria V. Girart et al.
JOURNAL OF IMMUNOLOGY (2007)
The relationship of anti-MICA antibodies and MICA expression with heart allograft rejection
B. Suarez-Alvarez et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2007)
RAET1E2, a soluble isoform of the UL16-binding protein RAET1E produced by tumor cells, inhibits NKG2D-mediated NK cytotoxicity
Wei Cao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
In Vivo Expression Pattern of MICA and MICB and Its Relevance to Auto-Immunity and Cancer
Stephanie Schrambach et al.
PLOS ONE (2007)
Histone deacetylase inhibitors suppress natural killer cell cytolytic activity
Henry Ogbomo et al.
FEBS LETTERS (2007)
Association of polymorphic extracellular domains of MICA with cervical cancer in northeastern Thai population
A. Jumnainsong et al.
TISSUE ANTIGENS (2007)
Calreticulin exposure dictates the immunogenicity of cancer cell death
Michel Obeid et al.
NATURE MEDICINE (2007)
Leveraging the immune system during chemotherapy: Moving calreticulin to the cell surface converts apoptotic death from Silent to immunogenic
Michel Obeid et al.
CANCER RESEARCH (2007)
Developmental pathways that generate natural-killer-cell diversity in mice and humans
Nicholas D. Huntington et al.
NATURE REVIEWS IMMUNOLOGY (2007)
TGF-β and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells
Guenter Eisele et al.
BRAIN (2006)
ULBPs, human ligands of the NKG2D receptor, stimulate tumor immunity with enhancement by IL-15
Claire L. Sutherland et al.
BLOOD (2006)
Therapy-induced antibodies to MHC class I chain-related protein A antagonize immune suppression and stimulate antitumor cytotoxicity
Masahisa Jinushi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Expression of the stress-related MHC class I chain-related protein MICA is an indicator of good prognosis in colorectal cancer patients
NFS Watson et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Proteolytic release of soluble UL16-binding protein 2 from tumor cells
I Waldhauer et al.
CANCER RESEARCH (2006)
CD4+-CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer
MJ Smyth et al.
JOURNAL OF IMMUNOLOGY (2006)
Soluble ULBP suppresses natural killer cell activity via down-regulating NKG2D expression
Hyunkeun Song et al.
CELLULAR IMMUNOLOGY (2006)
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
S Minucci et al.
NATURE REVIEWS CANCER (2006)
Anticancer activities of histone deacetylase inhibitors
Jessica E. Bolden et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death
N Casares et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B
S Skov et al.
CANCER RESEARCH (2005)
CD4+ CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-β-dependent manner
F Ghiringhelli et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Inhibition of NK cell activity through TGF-β1 by down-regulation of NKG2D in a murine model of head and neck cancer
S Dasgupta et al.
JOURNAL OF IMMUNOLOGY (2005)
NKG2D function protects the host from tumor initiation
MJ Smyth et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
S Gasser et al.
NATURE (2005)
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-γ production
OM Hart et al.
JOURNAL OF IMMUNOLOGY (2005)
Systemic NKG2D down-regulation impairs NK and CD8 T cell responses in vivo
K Wiemann et al.
JOURNAL OF IMMUNOLOGY (2005)
Natural killer cell-mediated lysis of hepatoma cells via specific induction of NKG2D Ligands by the histone deacetylase inhibitor sodium valproate
S Armeanu et al.
CANCER RESEARCH (2005)
Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer
JS Miller et al.
BLOOD (2005)
Effect of human cytomegalovirus on expression of MHC class I-related chains A
YZ Zou et al.
JOURNAL OF IMMUNOLOGY (2005)
Contribution of MHC class I chain-related A (MICA) gene polymorphism to genetic susceptibility for systemic lupus erythematosus
G Gambelunghe et al.
RHEUMATOLOGY (2005)
Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D
L Bacon et al.
JOURNAL OF IMMUNOLOGY (2004)
CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: Induction of cytokine release and cytotoxicity against tumors and dendritic cells
S Sivori et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia
HR Salih et al.
BLOOD (2003)
ULBP4 is a novel ligand for human NKG2D
NJ Chalupny et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors:: Consequences for the NK-mediated killing of dendritic cells
R Castriconi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
V Groh et al.
NATURE (2002)
Cutting edge: Down-regulation of MICA on human tumors by proteolytic shedding
HR Salih et al.
JOURNAL OF IMMUNOLOGY (2002)
High frequency of MIC null haplotype (HLA-B48-MICA-del-MICB*0107 N) in the Angaite Amerindian community in Paraguay
K Aida et al.
IMMUNOGENETICS (2002)
Codominant expression of the polymorphic MICA alloantigens encoded by genes in the HLA region
LL Molinero et al.
EUROPEAN JOURNAL OF IMMUNOGENETICS (2002)
Identification of the nonclassical HLA molecules, MICA, as targets for humoral immunity associated with irreversible rejection of kidney allografts
S Sumitran-Holgersson et al.
TRANSPLANTATION (2002)
Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
L Ruggeri et al.
SCIENCE (2002)
Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo
A Cerwenka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity
A Diefenbach et al.
NATURE (2001)
MICA and MICB genes:: can the enigma of their polymorphism be resolved?
HAF Stephens
TRENDS IN IMMUNOLOGY (2001)
ULBPs, novel MHC class I-related molecules bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
D Cosman et al.
IMMUNITY (2001)
Wide distribution of the MICA-MICB null haplotype in East Asians
M Komatsu-Wakui et al.
TISSUE ANTIGENS (2001)
Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population
K Imai et al.
LANCET (2000)
PERB11 (MIC): a polymorphic MHC gene is expressed in skin and single nucleotide polymorphisms are associated with psoriasis
GK Tay et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2000)
Identification of MICA as a new polymorphic alloantigen recognized by antibodies in sera of organ transplant recipients
NW Zwirner et al.
HUMAN IMMUNOLOGY (2000)
On the MICA deleted-MICB null, HLA-B*4801 haplotype
M Ota et al.
TISSUE ANTIGENS (2000)