4.8 Article

Safety and Preliminary Efficacy of a Novel Host-Modulatory Therapy for Reducing Gingival Inflammation

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Regression of human coronary artery plaque is associated with a high ratio of (18-hydroxy-eicosapentaenoic acid plus resolvin E1) to leukotriene B4

Francine K. Welty et al.

Summary: The presence of higher levels of EPA+DHA in the plasma was associated with increased levels of two SPMs, resolvin E1 and maresin 1, as well as HEPE. Patients with low EPA+DHA levels had a low (18-HEPE+resolvin E1)/LTB4 ratio and showed significant plaque progression, while those with high levels had either low ratios with progression or high ratios with regression. This suggests that an imbalance between pro-resolving and proinflammatory lipid mediators is linked to plaque progression in CAD patients, potentially explaining the benefits of EPA and DHA.

FASEB JOURNAL (2021)

Review Chemistry, Medicinal

Therapeutic Potential of Lipoxin A4 in Chronic Inflammation: Focus on Cardiometabolic Disease

Ting Fu et al.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2020)

Review Biochemistry & Molecular Biology

New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration

Charles N. Serhan et al.

MOLECULAR ASPECTS OF MEDICINE (2018)

Article Endocrinology & Metabolism

Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis

Eoin P. Brennan et al.

DIABETES (2018)

Review Biochemistry & Molecular Biology

Pro-resolving mediators in the regulation of periodontal disease

Thomas E. Van Dyke

MOLECULAR ASPECTS OF MEDICINE (2017)

Article Immunology

Resolvin E1 Reverses Experimental Periodontitis and Dysbiosis

Chun-Teh Lee et al.

JOURNAL OF IMMUNOLOGY (2016)

Article Hematology

Resolvin E1 (RvE1) Attenuates Atherosclerotic Plaque Formation in Diet and Inflammation-Induced Atherogenesis

Hatice Hasturk et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2015)

Review Pharmacology & Pharmacy

Lipoxins and aspirin-triggered lipoxins in resolution of inflammation

Mario Romano et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2015)

Review Biotechnology & Applied Microbiology

Physiological Impact of Abnormal Lipoxin A(4) Production on Cystic Fibrosis Airway Epithelium and Therapeutic Potential

Gerard Higgins et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Article Immunology

Impact of Resolvin E1 on Murine Neutrophil Phagocytosis in Type 2 Diabetes

Bruno S. Herrera et al.

INFECTION AND IMMUNITY (2015)

Article Dentistry, Oral Surgery & Medicine

Proresolving Nanomedicines Activate Bone Regeneration in Periodontitis

T. E. Van Dyke et al.

JOURNAL OF DENTAL RESEARCH (2015)

Article Cell Biology

Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue

Romain A. Colas et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2014)

Review Dentistry, Oral Surgery & Medicine

Global Burden of Severe Periodontitis in 1990-2010: A Systematic Review and Metaregression

N. J. Kassebaum et al.

JOURNAL OF DENTAL RESEARCH (2014)

Review Dentistry, Oral Surgery & Medicine

Global Burden of Severe Tooth Loss: A Systematic Review and Meta-analysis

N. J. Kassebaum et al.

JOURNAL OF DENTAL RESEARCH (2014)

Article Biochemistry & Molecular Biology

Lipoxin A4 attenuates adipose inflammation

Emma Boergeson et al.

FASEB JOURNAL (2012)

Article Dentistry, Oral Surgery & Medicine

Examiner alignment and assessment in clinical periodontal research

Arthur F. Hefti et al.

PERIODONTOLOGY 2000 (2012)

Article Biochemistry & Molecular Biology

Lipoxin A4 and benzo-lipoxin A4 attenuate experimental renal fibrosis

Emma Boergeson et al.

FASEB JOURNAL (2011)

Article Dentistry, Oral Surgery & Medicine

Proresolving lipid mediators: potential for prevention and treatment of periodontitis

Thomas E. Van Dyke

JOURNAL OF CLINICAL PERIODONTOLOGY (2011)

Article Microbiology

Review of osteoimmunology and the host response in endodontic and periodontal lesions

Dana T. Graves et al.

Journal of Oral Microbiology (2011)

Article Biochemistry & Molecular Biology

Anti-inflammatory and pro-resolving properties of benzo-lipoxin A4 analogs

Yee-Ping Sun et al.

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2009)

Editorial Material Dentistry, Oral Surgery & Medicine

Inflammation and Periodontal Diseases: A Reappraisal

Thomas E. Van Dyke

JOURNAL OF PERIODONTOLOGY (2008)

Article Biochemistry & Molecular Biology

RvE1 protects from local inflammation and osteoclast- mediated bone destruction in periodontitis

H. Hasturk et al.

FASEB JOURNAL (2006)

Article Dentistry, Oral Surgery & Medicine

Immune response: The key to bone resorption in periodontal disease

MA Taubman et al.

JOURNAL OF PERIODONTOLOGY (2005)

Review Gastroenterology & Hepatology

Lipoxins: Pro-resolution lipid mediators in intestinal inflammation

J Goh et al.

GASTROENTEROLOGY (2003)