4.6 Article

Additive Manufacturing of Bone Scaffolds Using PolyJet and Stereolithography Techniques

Journal

APPLIED SCIENCES-BASEL
Volume 11, Issue 16, Pages -

Publisher

MDPI
DOI: 10.3390/app11167336

Keywords

scaffold design; 3D-printed porous scaffold structures; trabecular bone; permeability; mechanical properties

Funding

  1. Key Action 1 Erasmus+ International Credit Mobility programme [KA107-000598]
  2. Science Foundation Ireland (SFI) [16/RC/3872]
  3. European Regional Development Fund
  4. Faculty of Engineering and Computing, Dublin City University

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This study investigates the printing capability of PolyJet and mu SLA 3D printing techniques for bone scaffold fabrication. By comparing the advantages and drawbacks, along with permeability and mechanical properties, it is found that scaffold structures printed with the mu SLA printer demonstrate higher performance.
In this study, the printing capability of two different additive manufacturing (3D printing) techniques, namely PolyJet and micro-stereolithography (mu SLA), are investigated regarding the fabrication of bone scaffolds. The 3D-printed scaffold structures are used as supports in replacing and repairing fractured bone tissue. Printed bone scaffolds with complex structures produced using additive manufacturing technology can mimic the mechanical properties of natural human bone, providing lightweight structures with modifiable porosity levels. In this study, 3D scaffold structures are designed with different combinations of architectural parameters. The dimensional accuracy, permeability, and mechanical properties of complex 3D-printed scaffold structures are analyzed to compare the advantages and drawbacks associated with the two techniques. The fluid flow rates through the 3D-printed scaffold structures are measured and Darcy's law is applied to calculate the experimentally measured permeability. The Kozeny-Carman equation is applied for theoretical calculation of permeability. Compression tests were performed on the printed samples to observe the effects of the printing techniques on the mechanical properties of the 3D-printed scaffold structures. The effect of the printing direction on the mechanical properties of the 3D-printed scaffold structures is also analyzed. The scaffold structures printed with the mu SLA printer demonstrate higher permeability and mechanical properties as compared to those printed using the PolyJet technique. It is demonstrated that both the mu SLA and PolyJet printing techniques can be used to print 3D scaffold structures with controlled porosity levels, providing permeability in a similar range to human bone.

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