4.6 Article

Developing human pluripotent stem cell-based cerebral organoids with a controllable microglia ratio for modeling brain development and pathology

Related references

Note: Only part of the references are listed.
Article Neurosciences

Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer's disease

Sudha R. Guttikonda et al.

Summary: The study utilizes a human pluripotent stem cell-derived tri-culture system to model neuroinflammation in Alzheimer's disease and identifies the critical role of reciprocal signaling between microglia and astrocytes in exacerbating the inflammatory response.

NATURE NEUROSCIENCE (2021)

Article Cell & Tissue Engineering

Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation

Xuyu Qian et al.

CELL STEM CELL (2020)

Editorial Material Cell & Tissue Engineering

High-Fidelity Modeling of Human Microglia with Pluripotent Stem Cells

Peng Jiang et al.

CELL STEM CELL (2020)

Review Clinical Neurology

Neurological associations of COVID-19

Mark A. Ellul et al.

LANCET NEUROLOGY (2020)

Editorial Material Multidisciplinary Sciences

How synaptic pruning shapes neural wiring during development and, possibly, in disease

Jill Sakai

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Neurosciences

Upgrading the Physiological Relevance of Human Brain Organoids

Ashley Del Dosso et al.

NEURON (2020)

Article Multidisciplinary Sciences

Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice

Claudia P. Figueiredo et al.

NATURE COMMUNICATIONS (2019)

Article Neurosciences

Modelling microglial function with induced pluripotent stem cells: an update

Jennifer M. Pocock et al.

NATURE REVIEWS NEUROSCIENCE (2018)

Article Multidisciplinary Sciences

Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

Laetitia Weinhard et al.

NATURE COMMUNICATIONS (2018)

Review Neurosciences

Microglial signatures and their role in health and disease

Oleg Butovsky et al.

NATURE REVIEWS NEUROSCIENCE (2018)

Article Multidisciplinary Sciences

Microglia innately develop within cerebral organoids

Paul R. Ormel et al.

NATURE COMMUNICATIONS (2018)

Article Microbiology

Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres

Celina Monteiro Abreu et al.

FRONTIERS IN MICROBIOLOGY (2018)

Review Immunology

Microglia and macrophages in brain homeostasis and disease

Qingyun Li et al.

NATURE REVIEWS IMMUNOLOGY (2018)

Review Neurosciences

The role of peripheral immune cells in the CNS in steady state and disease

Marco Prinz et al.

NATURE NEUROSCIENCE (2017)

Article Neurosciences

Transcriptomic analysis of purified human cortical microglia reveals age-associated changes

Thais F. Galatro et al.

NATURE NEUROSCIENCE (2017)

Review Neurosciences

The use of brain organoids to investigate neural development and disease

Elizabeth Di Lullo et al.

NATURE REVIEWS NEUROSCIENCE (2017)

Article Multidisciplinary Sciences

An environment-dependent transcriptional network specifies human microglia identity

David Gosselin et al.

SCIENCE (2017)

Article Cell & Tissue Engineering

Directed Differentiation of Human Pluripotent Stem Cells to Microglia

Panagiotis Douvaras et al.

STEM CELL REPORTS (2017)

Article Biochemistry & Molecular Biology

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

Xuyu Qian et al.

Review Immunology

Tissue-Resident Macrophage Ontogeny and Homeostasis

Florent Ginhoux et al.

IMMUNITY (2016)

Article Biochemistry & Molecular Biology

Efficient derivation of microglia-like cells from human pluripotent stem cells

Julien Muffat et al.

NATURE MEDICINE (2016)

Article Multidisciplinary Sciences

Complement and microglia mediate early synapse loss in Alzheimer mouse models

Soyon Hong et al.

SCIENCE (2016)

Review Cell Biology

Microglia: Architects of the Developing Nervous System

Jeffrey L. Frost et al.

TRENDS IN CELL BIOLOGY (2016)

Review Cell Biology

Microglia: Multitasking Specialists of the Brain

Alessandra Maria Casano et al.

DEVELOPMENTAL CELL (2015)

Review Immunology

Regulation of type I interferon responses

Lionel B. Ivashkiv et al.

NATURE REVIEWS IMMUNOLOGY (2014)

Article Cell Biology

Regulation of synapse composition by protein acetylation: the role of acetylated cortactin

Tatiana Catarino et al.

JOURNAL OF CELL SCIENCE (2013)

Article Neurosciences

Microglia Regulate the Number of Neural Precursor Cells in the Developing Cerebral Cortex

Christopher L. Cunningham et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

Wenlin Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

Florent Ginhoux et al.

SCIENCE (2010)

Article Biotechnology & Applied Microbiology

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Stuart M. Chambers et al.

NATURE BIOTECHNOLOGY (2009)

Review Biochemistry & Molecular Biology

Nestin expression - a property of multi-lineage progenitor cells?

C Wiese et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2004)