Journal
STEM CELL REPORTS
Volume 16, Issue 8, Pages 1853-1867Publisher
CELL PRESS
DOI: 10.1016/j.stemcr.2021.07.009
Keywords
-
Categories
Funding
- Innovative Medicines Initiative 2 Joint Undertaking (JU) [821362]
- EU's Horizon 2020 research and innovation program
- EFPIA
Ask authors/readers for more resources
The generation of disease-relevant human induced pluripotent stem cells requires adherence to ethical, legal, and quality standards, with best practices integrated into daily operations for maximizing their potential. Key experiences from operating the European Bank for induced Pluripotent Stem Cells (EBiSC) over 7 years are discussed, with recommendations on how to incorporate solutions into daily management framework.
Disease-relevant human induced pluripotent stem cells (iPSCs) are generated worldwide for research purposes; however, without robust and practical ethical, legal, and quality standards, there is a high risk that their true potential will not be realized. Best practices for tissue procurement, iPSC reprogramming, day-to-day cultivation, quality control, and data management aligned with an ethical and legal framework must be included into daily operations to ensure their promise is maximized. Here we discuss key learning experiences from 7 years of operating the European Bank for induced Pluripotent Stem Cells (EBiSC) and recommend how to incorporate solutions into a daily management framework.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available