Hybrid Materials Based on Multi-Walled Carbon Nanotubes and Nanoparticles with Antimicrobial Properties

In this study, multi-walled carbon nanotubes (MWCNTs) were decorated with different types of nanoparticles (NPs) in order to obtain hybrid materials with improved antimicrobial activity. Structural and morphological analysis, such as Fourier transformed infrared spectroscopy, Raman spectroscopy, X-ray diffraction, transmission electron microscopy, environmental scanning electron microscopy/energy-dispersive X-ray spectroscopy and the Brunauer-Emmett-Teller technique were used in order to investigate the decoration of the nanotubes with NPs. Analysis of the decorated nanotubes showed a narrow size distribution of NPs, 7-13 nm for the nanotubes decorated with zinc oxide (ZnO) NPs, 15-33 nm for the nanotubes decorated with silver (Ag) NPs and 20-35 nm for the nanotubes decorated with hydroxyapatite (HAp) NPs, respectively. The dispersion in water of the obtained nanomaterials was improved for all the decorated MWCNTs, as revealed by the relative absorbance variation in time of the water-dispersed nanomaterials. The obtained nanomaterials showed a good antimicrobial activity; however, the presence of the NPs on the surface of MWCNTs improved the nanocomposites' activity. The presence of ZnO and Ag nanoparticles enhanced the antimicrobial properties of the material, in clinically relevant microbial strains. Our data proves that such composite nanomaterials are efficient antimicrobial agents, suitable for the therapy of severe infection and biofilms.

Automated summary

Multi-walled carbon nanotubes (MWCNTs) were decorated with different types of nanoparticles (NPs) to obtain hybrid materials with improved antimicrobial activity, showing good antimicrobial properties in clinically relevant microbial strains. The presence of NPs on the surface of MWCNTs enhanced the nanocomposites' activity, with zinc oxide and silver nanoparticles improving the antimicrobial properties of the material.