4.7 Review

Ionic Liquid-Based Materials for Biomedical Applications

Journal

NANOMATERIALS
Volume 11, Issue 9, Pages -

Publisher

MDPI
DOI: 10.3390/nano11092401

Keywords

biomedical applications; ionic liquids; IL-polymer based materials

Funding

  1. FCT (Fundacao para a Ciencia e Tecnologia) [UID/FIS/04650/2019, PTDC/BTM-MAT/28237/2017, PTDC/EMD-EMD/28159/2017, PTDC/FIS-MAC/28157/2017, LungChek ENMed/0049/2016, SFRH/BPD/121526/2016, SFRH/BD/145345/2019, FRH/BD/148655/2019, SFRH/BPD/121464/2016, CR: 2020.04163.CEECIND]
  2. State Research Agency (AEI) [PID2019-106099RB-C43/AEI/10.13039/501100011033]
  3. Basque Government Industry Department: ELKARTE
  4. Fundação para a Ciência e a Tecnologia [SFRH/BD/145345/2019, SFRH/BPD/121464/2016] Funding Source: FCT

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Ionic liquids (ILs) have been extensively explored and applied in various fields, especially in biomedicine. They have unique properties that allow for the development of materials with specific functionalities, including improved dissolution and processability, when combined with natural and synthetic polymers. This review focuses on the recent advances of ILs in developing biomaterials for biomedical applications such as drug delivery, cancer therapy, tissue engineering, antimicrobial agents, and biosensing.
Ionic liquids (ILs) have been extensively explored and implemented in different areas, ranging from sensors and actuators to the biomedical field. The increasing attention devoted to ILs centers on their unique properties and possible combination of different cations and anions, allowing the development of materials with specific functionalities and requirements for applications. Particularly for biomedical applications, ILs have been used for biomaterials preparation, improving dissolution and processability, and have been combined with natural and synthetic polymer matrixes to develop IL-polymer hybrid materials to be employed in different fields of the biomedical area. This review focus on recent advances concerning the role of ILs in the development of biomaterials and their combination with natural and synthetic polymers for different biomedical areas, including drug delivery, cancer therapy, tissue engineering, antimicrobial and antifungal agents, and biosensing.

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