Related references
Note: Only part of the references are listed.Saroglitazar, a PPAR-α/γ Agonist, for Treatment of Nonalcoholic Fatty Liver Disease: A Randomized Controlled Double-Blind Phase 2 Trial
Manas Kumar Panigrahi et al.
JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2022)
The Power of Plasticity?Metabolic Regulation of Hepatic Stellate Cells
Parth Trivedi et al.
CELL METABOLISM (2021)
Combination Therapies Including Cilofexor and Firsocostat for Bridging Fibrosis and Cirrhosis Attributable to NASH
Rohit Loomba et al.
HEPATOLOGY (2021)
Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease
Chris E. Shannon et al.
MOLECULAR METABOLISM (2021)
NAFLD: Reporting Histologic Findings in Clinical Practice
Elizabeth M. Brunt et al.
HEPATOLOGY (2021)
Acetylation of lactate dehydrogenase B drives NAFLD progression by impairing lactate clearance
Tongxin Wang et al.
JOURNAL OF HEPATOLOGY (2021)
Saroglitazar, a PPAR-α/γ Agonist, for Treatment of NAFLD: A Randomized Controlled Double-Blind Phase 2 Trial
Samer Gawrieh et al.
HEPATOLOGY (2021)
Mitochondrial TCA cycle metabolites control physiology and disease
Inmaculada Martinez-Reyes et al.
NATURE COMMUNICATIONS (2020)
Associations between obesity and metabolic health with nonalcoholic fatty liver disease in elderly Chinese
Li-Ming Wu et al.
HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL (2020)
Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease
Panu K. Luukkonen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver
David A. Cappel et al.
CELL METABOLISM (2019)
The Liver as an Endocrine Organ-Linking NAFLD and Insulin Resistance
Matthew J. Watt et al.
ENDOCRINE REVIEWS (2019)
A Mitochondrial VDAC1-Based Peptide Greatly Suppresses Steatosis and NASH-Associated Pathologies in a Mouse Model
Srinivas Pittala et al.
MOLECULAR THERAPY (2019)
Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches
Karen G. de la Cruz-Lopez et al.
FRONTIERS IN ONCOLOGY (2019)
Modulation of Insulin Resistance in Nonalcoholic Fatty Liver Disease
Reenam S. Khan et al.
HEPATOLOGY (2019)
Evaluation of Dietary Approaches for the Treatment of Non-Alcoholic Fatty Liver Disease: A Systematic Review
Naba Saeed et al.
NUTRIENTS (2019)
Impaired ketogenesis and increased acetyl-CoA oxidation promote hyperglycemia in human fatty liver
Justin A. Fletcher et al.
JCI INSIGHT (2019)
Involvement of the Warburg effect in non-tumor diseases processes
Zhe Chen et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2018)
Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention
Zobair Younossi et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)
Biochemical and cellular properties of insulin receptor signalling
Rebecca A. Haeusler et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome
Lotte Kors et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
The Science and Translation of Lactate Shuttle Theory
George A. Brooks
CELL METABOLISM (2018)
Acetyl-CoA carboxylase Inhibitor GS-0976 for 12 Weeks Reduces Hepatic De Novo Lipogenesis and Steatosis in Patients With Nonalcoholic Steatohepatitis
Eric J. Lawitz et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2018)
Molecular Actions of PPARα in Lipid Metabolism and Inflammation
Nadia Bougarne et al.
ENDOCRINE REVIEWS (2018)
Geranylgeranyl diphosphate synthase (GGPPS) regulates non-alcoholic fatty liver disease (NAFLD)-fibrosis progression by determining hepatic glucose/fatty acid preference under high-fat diet conditions
Jia Liu et al.
JOURNAL OF PATHOLOGY (2018)
Mechanisms of NAFLD development and therapeutic strategies
Scott L. Friedman et al.
NATURE MEDICINE (2018)
MECHANISMS OF INSULIN ACTION AND INSULIN RESISTANCE
Max C. Petersen et al.
PHYSIOLOGICAL REVIEWS (2018)
GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease
Rohit Loomba et al.
GASTROENTEROLOGY (2018)
Mitochondrial Dysfunction and Signaling in Chronic Liver Diseases
Abdellah Mansouri et al.
GASTROENTEROLOGY (2018)
NAFLD and diabetes mellitus
Herbert Tilg et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)
New trends on obesity and NAFLD in Asia
Jian-Gao Fan et al.
JOURNAL OF HEPATOLOGY (2017)
Regulation of hepatic glucose metabolism in health and disease
Max C. Petersen et al.
NATURE REVIEWS ENDOCRINOLOGY (2017)
Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance
Joonseok Cho et al.
NATURE COMMUNICATIONS (2017)
Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics
Patrycja Puchalska et al.
CELL METABOLISM (2017)
Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity
Rainey E. Patterson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2016)
Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis
Younghoon Go et al.
DIABETES (2016)
The 11β-hydroxysteroid dehydrogenase type 1 inhibitor protects against the insulin resistance and hepatic steatosis in db/db mice
Xiaohuan Yuan et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2016)
Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening
Vlad Ratziu et al.
GASTROENTEROLOGY (2016)
Global Epidemiology of Nonalcoholic Fatty Liver Disease-Meta-Analytic Assessment of Prevalence, Incidence, and Outcomes
Zobair M. Younossi et al.
HEPATOLOGY (2016)
ROS Generation in Peroxisomes and its Role in Cell Signaling
Luis A. del Rio et al.
PLANT AND CELL PHYSIOLOGY (2016)
The Warburg effect in tumor progression: Mitochondrial oxidative metabolism as an anti-metastasis mechanism
Jianrong Lu et al.
CANCER LETTERS (2015)
Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis
Chrysi Koliaki et al.
CELL METABOLISM (2015)
Redox Homeostasis and Mitochondrial Dynamics
Peter H. G. M. Willems et al.
CELL METABOLISM (2015)
Fibrosis Progression in Nonalcoholic Fatty Liver vs Nonalcoholic Steatohepatitis: A Systematic Review and Meta-analysis of Paired-Biopsy Studies
Siddharth Singh et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2015)
NAFLD: A multisystem disease
Christopher D. Byrne et al.
JOURNAL OF HEPATOLOGY (2015)
Transcriptional regulation of hepatic lipogenesis
Yuhui Wang et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease
Jennifer E. Lambert et al.
GASTROENTEROLOGY (2014)
Comprehensive review on lactate metabolism in human health
M. Adeva-Andany et al.
MITOCHONDRION (2014)
MITOCHONDRIAL REACTIVE OXYGEN SPECIES (ROS) AND ROS-INDUCED ROS RELEASE
Dmitry B. Zorov et al.
PHYSIOLOGICAL REVIEWS (2014)
Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis
Cindy Hodakoski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease
Yuki Kawano et al.
JOURNAL OF GASTROENTEROLOGY (2013)
Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: A systematic review
Christian Thoma et al.
JOURNAL OF HEPATOLOGY (2012)
Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver
Santhosh Satapati et al.
JOURNAL OF LIPID RESEARCH (2012)
PPARγ contributes to PKM2 and HK2 expression in fatty liver
Ganna Panasyuk et al.
NATURE COMMUNICATIONS (2012)
Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease
Nishanth E. Sunny et al.
CELL METABOLISM (2011)
Fatty acid omega-oxidation as a rescue pathway for fatty acid oxidation disorders in humans
Ronald J. A. Wanders et al.
FEBS JOURNAL (2011)
Otto Warburg's contributions to current concepts of cancer metabolism
Willem H. Koppenol et al.
NATURE REVIEWS CANCER (2011)
Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis
Hyun-Seok Kim et al.
CELL METABOLISM (2010)
The mitochondrial respiratory chain
Peter R. Rich et al.
ESSAYS IN BIOCHEMISTRY: MITOCHONDRIAL FUNCTION (2010)
Fatty Acid Metabolism in the Liver, Measured by Positron Emission Tomography, Is Increased in Obese Individuals
Patricia Iozzo et al.
GASTROENTEROLOGY (2010)
Apoptosis is associated with CD36/fatty acid translocase upregulation in non-alcoholic steatohepatitis
Lars P. Bechmann et al.
LIVER INTERNATIONAL (2010)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior
Roy L. Silverstein et al.
SCIENCE SIGNALING (2009)
Selective versus total insulin resistance: A pathogenic paradox
Michael S. Brown et al.
CELL METABOLISM (2008)
Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease
Elisa Fabbrini et al.
GASTROENTEROLOGY (2008)
Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury
G. Serviddio et al.
GUT (2008)
Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease
Nobito Higuchi et al.
HEPATOLOGY RESEARCH (2008)
Increased expression of hepatic pyruvate dehydrogenase kinases 2 and 4 in young and middle-aged Otsuka Long-Evans Tokushima Fatty rats: induction by elevated levels of free fatty acids
G Bajotto et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2006)
Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver
R Dentin et al.
BIOCHIMIE (2005)
Lactate metabolism: a new paradigm for the third millennium
LB Gladden
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis
M Pérez-Carreras et al.
HEPATOLOGY (2003)
Hepatic mitochondrial beta-oxidation in patients with nonalcoholic steatohepatitis assessed by 13C-octanoate breath test
L Miele et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2003)
The key role of anaplerosis and cataplerosis for citric acid cycle function
OE Owen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The remarkable structural and functional organization of the eukaryotic pyruvate dehydrogenase complexes
ZH Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Nonalcoholic steatosis and steatohepatitis -: III.: Peroxisomal β-oxidation, PPARα, and steatohepatitis
JK Reddy
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2001)
Gene expression of tumor necrosis factor α and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients
J Crespo et al.
HEPATOLOGY (2001)
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
AJ Sanyal et al.
GASTROENTEROLOGY (2001)
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ
JJ Repa et al.
GENES & DEVELOPMENT (2000)
Share Paper
