4.7 Article

Phillygenin Attenuates Carbon Tetrachloride-Induced Liver Fibrosis via Modulating Inflammation and Gut Microbiota

Related references

Note: Only part of the references are listed.
Article Biotechnology & Applied Microbiology

Hepatoprotective Effect of Probiotic Lactic Acid Bacteria on Thioacetamide-Induced Liver Fibrosis in Rats

Chittapon Jantararussamee et al.

Summary: The study demonstrates that probiotic lactic acid bacteria can attenuate the development of liver fibrosis in rats, reduce liver damage and inflammation, and lower liver enzyme levels.

PROBIOTICS AND ANTIMICROBIAL PROTEINS (2021)

Article Pharmacology & Pharmacy

The antimicrobial peptide YD attenuates inflammation via miR-155 targeting CASP12 during liver fibrosis

Zhibin Yan et al.

Summary: The study demonstrates that YD alleviates inflammation caused by liver fibrosis through the miR-155-Casp12-NF-kappa B axis, indicating its potential as a therapeutic candidate for hepatic fibrosis.

ACTA PHARMACEUTICA SINICA B (2021)

Article Nutrition & Dietetics

Dietary fiber regulates intestinal flora and suppresses liver and systemic inflammation to alleviate liver fibrosis in mice

Ming-mei Li et al.

Summary: Increasing dietary fiber intake can prevent liver fibrosis in mice by reducing proinflammatory factors, enhancing immune response, regulating gut microbiota structure, and reducing T lymphocyte infiltration, suggesting that dietary therapy may alleviate liver fibrosis.

NUTRITION (2021)

Review Health Care Sciences & Services

Traditional Chinese medicine, liver fibrosis, intestinal flora: is there any connection?-a narrative review

Yu-Tong Liu et al.

Summary: This study analyzed the regulation of liver fibrosis pathogenesis by intestinal flora and evaluated the effect of traditional Chinese medicine on the intestinal flora, providing new insights into liver fibrosis treatment. It was found that traditional Chinese medicine can effectively regulate the intestinal flora, aiding in the prevention and treatment of liver fibrosis through the liver-intestine axis. The study highlights the importance of maintaining a healthy intestinal microbiome for liver health and outlines the potential of using traditional Chinese medicine in liver fibrosis prevention and treatment.

ANNALS OF PALLIATIVE MEDICINE (2021)

Review Gastroenterology & Hepatology

Molecular and cellular mechanisms of liver fibrosis and its regression

Tatiana Kisseleva et al.

Summary: Chronic liver injury results in liver inflammation and fibrosis, which can be reversed by eliminating activated myofibroblasts and resorbing the fibrous scar. Understanding the molecular mechanisms underlying liver fibrosis and its reversibility can lead to the identification of new therapeutic targets for liver fibrosis treatment.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

Review Medicine, Research & Experimental

Mechanisms of liver fibrosis and its role in liver cancer

Debanjan Dhar et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2020)

Review Gastroenterology & Hepatology

Contribution of the Intestinal Microbiome and Gut Barrier to Hepatic Disorders

Daniel M. Chopyk et al.

GASTROENTEROLOGY (2020)

Review Biochemistry & Molecular Biology

Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues

Maurizio Parola et al.

MOLECULAR ASPECTS OF MEDICINE (2019)

Article Biochemistry & Molecular Biology

Experimental study on the antioxidant activity of Malus hupehensis (Pamp.) Rehd extracts in vitro and in vivo

Ji Liu et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2019)

Review Medical Laboratory Technology

Role of the intestinal microbiome in liver fibrosis development and new treatment strategies

Rongrong Zhou et al.

TRANSLATIONAL RESEARCH (2019)

Article Pharmacology & Pharmacy

Ursolic Acid Improves Intestinal Damage and Bacterial Dysbiosis in Liver Fibrosis Mice

Si-Zhe Wan et al.

FRONTIERS IN PHARMACOLOGY (2019)

Article Gastroenterology & Hepatology

Blueberry Attenuates Liver Fibrosis, Protects Intestinal Epithelial Barrier, and Maintains Gut Microbiota Homeostasis

Zhiqiang Yan et al.

CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2019)

Article Gastroenterology & Hepatology

Tight junction proteins in gastrointestinal and liver disease

Mirjam B. Zeisel et al.

Review Gastroenterology & Hepatology

Liver fibrosis

M. Merve Aydin et al.

TURKISH JOURNAL OF GASTROENTEROLOGY (2018)

Article Biotechnology & Applied Microbiology

Evaluation of the Pharmacokinetics and Hepatoprotective Effects of Phillygenin in Mouse

Wei Song et al.

BIOMED RESEARCH INTERNATIONAL (2018)

Article Gastroenterology & Hepatology

Hepatocyte Autotaxin Expression Promotes Liver Fibrosis and Cancer

Eleanna Kaffe et al.

HEPATOLOGY (2017)

Review Gastroenterology & Hepatology

The gut microbiome and liver cancer: mechanisms and clinical translation

Le-Xing Yu et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)

Review Gastroenterology & Hepatology

Mechanisms of hepatic stellate cell activation

Takuma Tsuchida et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)

Review Gastroenterology & Hepatology

Regression of Liver Fibrosis

Lara Campana et al.

SEMINARS IN LIVER DISEASE (2017)

Review Medicine, General & Internal

Reversal of liver cirrhosis: current evidence and expectations

Young Kul Jung et al.

KOREAN JOURNAL OF INTERNAL MEDICINE (2017)

Review Pharmacology & Pharmacy

Pathophysiology of liver fibrosis and the methodological barriers to the development of anti-fibrogenic agents

Katrin Bottcher et al.

ADVANCED DRUG DELIVERY REVIEWS (2017)

Review Cell Biology

The Intestinal Immune System in Obesity and Insulin Resistance

Daniel A. Winer et al.

CELL METABOLISM (2016)

Article Gastroenterology & Hepatology

New Developments on the Treatment of Liver Fibrosis

Yukinori Koyama et al.

DIGESTIVE DISEASES (2016)

Review Gastroenterology & Hepatology

The role of the gut microbiota in NAFLD

Christopher Leung et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2016)

Article Veterinary Sciences

The carbon tetrachloride model in mice

D. Scholten et al.

LABORATORY ANIMALS (2015)

Review Gastroenterology & Hepatology

Reversibility of liver fibrosis

Mengxi Sun et al.

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2015)

Article Biochemical Research Methods

UPARSE: highly accurate OTU sequences from microbial amplicon reads

Robert C. Edgar

NATURE METHODS (2013)

Review Immunology

Pathogen Recognition by the Innate Immune System

Himanshu Kumar et al.

INTERNATIONAL REVIEWS OF IMMUNOLOGY (2011)

Article Biochemistry & Molecular Biology

Lignans from the Fruits of Forsythia suspensa (Thunb.) Vahl Protect High-Density Lipoprotein during Oxidative Stress

Min-Jung Chang et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2008)

Article Pharmacology & Pharmacy

The current state of serum biomarkers of hepatotoxicity

Josef Ozer et al.

TOXICOLOGY (2008)