4.7 Article

Naringin Chelates Excessive Iron and Prevents the Formation of Amyloid-Beta Plaques in the Hippocampus of Iron-Overloaded Mice

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

N,N '-1,10-Bis(Naringin) Triethylenetetraamine, Synthesis and as a Cu(II) Chelator for Alzheimer's Disease Therapy

Li-Xia Guo et al.

Summary: The bis-Schiff base of N,N'-1,10-bis(naringin) triethylenetetraamine shows potential as a therapy for Alzheimer's disease by promoting PC12 cell proliferation, inhibiting Cu2+-amyloid-beta mediated cytotoxicity, and attenuating A beta(1-42) aggregation. Additionally, the compound acts as a potent antioxidant by decreasing ROS levels and increasing SOD activity in treated cells.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2021)

Article Clinical Neurology

Brain iron deposition is linked with cognitive severity in Parkinson's disease

George Edward Calver Thomas et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2020)

Review Biochemistry & Molecular Biology

Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration

Shashank Masaldan et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Review Cell Biology

Flavonoids as Therapeutic Agents in Alzheimer's and Parkinson's Diseases: A Systematic Review of Preclinical Evidences

Roxana Braga de Andrade Teles et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

Article Biochemistry & Molecular Biology

Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer's Disease

Dong-Mei Wang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Article Pharmacology & Pharmacy

Iron overload-induced rat liver injury: Involvement of protein tyrosine nitration and the effect of baicalin

Yan Zhang et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2012)

Article Chemistry, Applied

Iron reduction potentiates hydroxyl radical formation only in flavonols

Katerina Macakova et al.

FOOD CHEMISTRY (2012)

Article Chemistry, Physical

The Binding of Fe(II)-Heme to the Amyloid Beta Peptide of Alzheimer's Disease: QM/MM Investigations

Samira Azimi et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2012)

Article Biochemistry & Molecular Biology

In vitro analysis of iron chelating activity of flavonoids

Premysl Mladenka et al.

JOURNAL OF INORGANIC BIOCHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat

Meherzia Mokni et al.

NEUROCHEMICAL RESEARCH (2007)

Article Pharmacology & Pharmacy

Dietary supplementation of baicalin and quercetin attenuates iron overload induced mouse liver injury

Y Zhang et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2006)

Article Biochemical Research Methods

Microanalysis of non-heme iron in animal tissues

CJ Rebouche et al.

JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS (2004)

Article Medical Laboratory Technology

Influence of naringin on ferric iron induced oxidative damage in vitro

GC Jagetia et al.

CLINICA CHIMICA ACTA (2004)

Review Neurosciences

Iron, brain ageing and neurodegenerative disorders

L Zecca et al.

NATURE REVIEWS NEUROSCIENCE (2004)