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Flavanols from Japanese Quince (Chaenomeles Japonica) Fruit Inhibit Human Prostate and Breast Cancer Cell Line Invasiveness and Cause Favorable Changes in Bax/Bcl-2 mRNA Ratio
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NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2013)
Apoptotic markers in a prostate cancer cell line: Effect of ellagic acid
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ONCOLOGY REPORTS (2013)
CDK2 and mTOR are direct molecular targets of isoangustone A in the suppression of human prostate cancer cell growth
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TOXICOLOGY AND APPLIED PHARMACOLOGY (2013)
Marchantin M: a novel inhibitor of proteasome induces autophagic cell death in prostate cancer cells
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CELL DEATH & DISEASE (2013)
Opposing Effects of Androgen Deprivation and Targeted Therapy on Prostate Cancer Prevention
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THERAPEUTIC ADVANCES IN UROLOGY (2013)
Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2
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CARCINOGENESIS (2012)
Abiraterone in Prostate Cancer: A New Angle to an Old Problem
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CLINICAL CANCER RESEARCH (2012)
Activin A Stimulates AKR1C3 Expression and Growth in Human Prostate Cancer
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ENDOCRINOLOGY (2012)
Ginsenoside Rg3 attenuates cell migration via inhibition of aquaporin 1 expression in PC-3M prostate cancer cells
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EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Mechanisms of natural brassinosteroid-induced apoptosis of prostate cancer cells
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FOOD AND CHEMICAL TOXICOLOGY (2012)
Oridonin Up-regulates Expression of P21 and Induces Autophagy and Apoptosis in Human Prostate Cancer Cells
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INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2012)
Antiproliferative effect of oleuropein in prostate cell lines
Rosaria Acquaviva et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt
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INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation
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Effects of Abiraterone Acetate on Androgen Signaling in Castrate-Resistant Prostate Cancer in Bone
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Niphatenones, Glycerol Ethers from the Sponge Niphates digitalis Block Androgen Receptor Transcriptional Activity in Prostate Cancer Cells: Structure Elucidation, Synthesis, and Biological Activity
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Phycocyanin Induces Apoptosis and Enhances the Effect of Topotecan on Prostate Cell Line LNCaP
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Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells
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NATURE (2012)
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
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NATURE GENETICS (2012)
Prostate cancer-from steroid transformations to clinical translation
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Correlation Analysis of JAK-STAT Pathway Components on Prognosis of Patients with Prostate Cancer
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PATHOLOGY & ONCOLOGY RESEARCH (2012)
Pseudolaric acid B induces apoptosis via proteasome-mediated Bcl-2 degradation in hormone-refractory prostate cancer DU145 cells
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BET domain co-regulators in obesity, inflammation and cancer
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Suppression of Prostate Cancer Cell Rolling and Adhesion to Endothelium by 1α,25-Dihydroxyvitamin D3
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AMERICAN JOURNAL OF PATHOLOGY (2011)
Physalins A and B Inhibit Androgen-Independent Prostate Cancer Cell Growth through Activation of Cell Apoptosis and Downregulation of Androgen Receptor Expression
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BIOLOGICAL & PHARMACEUTICAL BULLETIN (2011)
Garlic Constituent Diallyl Trisulfide Suppresses X-linked Inhibitor of Apoptosis Protein in Prostate Cancer Cells in Culture and In Vivo
Su-Hyeong Kim et al.
CANCER PREVENTION RESEARCH (2011)
Androgen receptor and its splice variants in prostate cancer
Simon Haile et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2011)
Invadosome regulation by adhesion signaling
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CURRENT OPINION IN CELL BIOLOGY (2011)
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
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ENDOCRINE REVIEWS (2011)
Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaid™: Mechanism of activity
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INTERNATIONAL JOURNAL OF ONCOLOGY (2011)
Androgen Receptor Rediscovered: The New Biology and Targeting the Androgen Receptor Therapeutically
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JOURNAL OF CLINICAL ONCOLOGY (2011)
Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice
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JOURNAL OF MOLECULAR MEDICINE-JMM (2011)
Reactive Oxygen Species-Dependent Apoptosis by Gugulipid Extract of Ayurvedic Medicine Plant Commiphora mukul in Human Prostate Cancer Cells Is Regulated by c-Jun N-Terminal Kinase
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MOLECULAR PHARMACOLOGY (2011)
Antiproliferative and cytotoxic activity of extracts from Cistus incanus L. and Cistus monspeliensis L. on human prostate cell lines
Federica Vitali et al.
NATURAL PRODUCT RESEARCH (2011)
Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
Kai-Hsiung Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Differential transformation capacity of Src family kinases during the initiation of prostate cancer
Houjian Cai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Lycopene Enhances Docetaxel's Effect in Castration-Resistant Prostate Cancer Associated with Insulin-like Growth Factor I Receptor Levels
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NEOPLASIA (2011)
Anibamine, a natural product CCR5 antagonist, as a novel lead for the development of anti-prostate cancer agents
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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Anticancer activity of a sub-fraction of dichloromethane extract of Strobilanthes crispus on human breast and prostate cancer cells in vitro
Nik Soriani Yaacob et al.
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2010)
Integrative Genomic Profiling of Human Prostate Cancer
Barry S. Taylor et al.
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Genistein and daidzein act on a panel of genes implicated in cell cycle and angiogenesis by Polymerase Chain Reaction arrays in human prostate cancer cell lines
Nadege Rabiau et al.
CANCER EPIDEMIOLOGY (2010)
Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells
Yewseok Suh et al.
CARCINOGENESIS (2010)
Isoliquiritigenin, a natural anti-oxidant, selectively inhibits the proliferation of prostate cancer cells
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CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2010)
Differential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cells
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EXPERIMENTAL BIOLOGY AND MEDICINE (2010)
Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: role of reactive oxygen species
Padma Sandeep Koka et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2010)
Pomegranate extract induces apoptosis in human prostate cancer cells by modulation of the IGF-IGFBP axis
Satomi Koyama et al.
GROWTH HORMONE & IGF RESEARCH (2010)
PectaSol-C Modified Citrus Pectin Induces Apoptosis and Inhibition of Proliferation in Human and Mouse Androgen-Dependent and -Independent Prostate Cancer Cells
Jun Yan et al.
INTEGRATIVE CANCER THERAPIES (2010)
Flavokawain B, a kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and Bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth
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INTERNATIONAL JOURNAL OF CANCER (2010)
Selenite triggers rapid transcriptional activation of p53, and p53-mediated apoptosis in prostate cancer cells: Implication for the treatment of early-stage prostate cancer
Sivalokanathan Sarveswaran et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2010)
Antineoplastic effect of β-elemene on prostate cancer cells and other types of solid tumour cells
Qingdi Quentin Li et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2010)
Tumor progression in the LPB-Tag transgenic model of prostate cancer is altered by vitamin D receptor and serum testosterone status
Sarah Mordan-McCombs et al.
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Cryptocaryone, a Natural Dihydrochalcone, Induces Apoptosis in Human Androgen Independent Prostate Cancer Cells by Death Receptor Clustering in Lipid Raft and Nonraft Compartments
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JOURNAL OF UROLOGY (2010)
Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells
Chi-Sheng Chien et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2010)
Tirucallic Acids Are Novel Pleckstrin Homology Domain-Dependent Akt Inhibitors Inducing Apoptosis in Prostate Cancer Cells
Aydee C. Estrada et al.
MOLECULAR PHARMACOLOGY (2010)
Vitamin D Binding Protein-Macrophage Activating Factor Directly Inhibits Proliferation, Migration, and uPAR Expression of Prostate Cancer Cells
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PLOS ONE (2010)
Insights into Ca2+ homeostasis of advanced prostate cancer cells
Matthieu Flourakis et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Serenoa repens extract targets mitochondria and activates the intrinsic apoptotic pathway in human prostate cancer cells
Antonella Baron et al.
BJU INTERNATIONAL (2009)
Reduced growth and integrin expression of prostate cells cultured with lycopene, vitamin E and fish oil in vitro
T. Bureyko et al.
BRITISH JOURNAL OF NUTRITION (2009)
Sodium selenite induces apoptosis by generation of superoxide via the mitochondrial-dependent pathway in human prostate cancer cells
Nong Xiang et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2009)
Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis
Ikuhiko Nakase et al.
CANCER LETTERS (2009)
Phenethyl isothiocyanate induces cell cycle arrest and reduction of alpha- and beta-tubulin isotypes in human prostate cancer cells
Ping Yin et al.
CELL BIOLOGY INTERNATIONAL (2009)
Vitexins, Nature-Derived Lignan Compounds, Induce Apoptosis and Suppress Tumor Growth
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CLINICAL CANCER RESEARCH (2009)
Inhibition of prostaglandin synthesis and actions by genistein in human prostate cancer cells and by soy isoflavones in prostate cancer patients
Srilatha Swami et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Effects of Pomegranate Chemical Constituents/Intestinal Microbial Metabolites on CYP1B1 in 22Rv1 Prostate Cancer Cells
Sashi G. Kasimsetty et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2009)
Epidithiodiketopiperazines Block the Interaction between Hypoxia-inducible Factor-1α (HIF-1α) and p300 by a Zinc Ejection Mechanism
Kristina M. Cook et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Magnolol Induces Apoptosis Via Inhibiting the EGFR/PI3K/Akt Signaling Pathway in Human Prostate Cancer Cells
Dae-Hee Lee et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2009)
Obovatol Enhances Docetaxel-Induced Prostate and Colon Cancer Cell Death Through Inactivation of Nuclear Transcription Factor-κB
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JOURNAL OF PHARMACOLOGICAL SCIENCES (2009)
Testosterone Therapy in Men With Prostate Cancer: Scientific and Ethical Considerations
Abraham Morgentaler
JOURNAL OF UROLOGY (2009)
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases
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MOLECULAR CELL (2009)
Targeting the phosphoinositide 3-kinase pathway in cancer
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NATURE REVIEWS DRUG DISCOVERY (2009)
Mechanism of androgen receptor action
Jin Li et al.
MATURITAS (2009)
Lycopene Effects Contributing to Prostate Health
Karin Wertz
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2009)
Gallic Acid, an Active Constituent of Grape Seed Extract, Exhibits Anti-proliferative, Pro-apoptotic and Anti-tumorigenic Effects Against Prostate Carcinoma Xenograft Growth in Nude Mice
Manjinder Kaur et al.
PHARMACEUTICAL RESEARCH (2009)
Androgen biosynthetic pathways in the human prostate
Van Luu-The et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
A Novel Dietary Flavonoid Fisetin Inhibits Androgen Receptor Signaling and Tumor Growth in Athymic Nude Mice
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CANCER RESEARCH (2008)
Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
Jennifer A. Locke et al.
CANCER RESEARCH (2008)
Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
R. Bruce Montgomery et al.
CANCER RESEARCH (2008)
Non-genomic actions of androgens
C. D. Foradori et al.
FRONTIERS IN NEUROENDOCRINOLOGY (2008)
Inhibition of epidermal growth factor receptor signaling pathway by delphinidin, an anthocyanidin in pigmented fruits and vegetables
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INTERNATIONAL JOURNAL OF CANCER (2008)
Effects of iejimalide B, a Marine Macrolide, on Growth and Apoptosis in Prostate Cancer Cell Lines
Wei-Lin Winnie Wang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2008)
Pomegranate polyphenols down-regulate expression of androgen-synthesizing genes in human prostate cancer cells overexpressing the androgen receptor
Mee Young Hong et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2008)
Src kinase potentiates androgen receptor transactivation function and invasion of androgen-independent prostate cancer C4-2 cells
M. Asim et al.
ONCOGENE (2008)
Bromodomain 4 activation predicts breast cancer survival
Nigel P. S. Crawford et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Experimental therapy of prostate cancer with novel natural product anti-cancer ginsenosides
Wei Wang et al.
PROSTATE (2008)
Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3
Rebecka Hellsten et al.
PROSTATE (2008)
The Dietary Bioflavonoid, Quercetin, Selectively Induces Apoptosis of Prostate Cancer Cells by Down-Regulating the Expression of Heat Shock Protein 90
Ravikumar Aalinkeel et al.
PROSTATE (2008)
Glycyrrhizin induces apoptosis in prostate cancer cell lines DU-145 and LNCaP
Sivasakthivel Thirugnanam et al.
ONCOLOGY REPORTS (2008)
Piplartine induces caspase-mediated apoptosis in PC-3 human prostate cancer cells
Eun-Hee Kong et al.
ONCOLOGY REPORTS (2008)
Pristimerin induces apoptosis by targeting the proteasome in prostate cancer cells
Huanjie Yang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2008)
Activation of the androgen receptor alters the intracellular calcium response 155 to glutamate in primary hippocampal neurons and modulates sarco/endoplasmic reticulum calcium ATPase 2 transcription
C. D. Foradori et al.
NEUROSCIENCE (2007)
A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth
Qianben Wang et al.
MOLECULAR CELL (2007)
Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer
L. Tam et al.
BRITISH JOURNAL OF CANCER (2007)
Differential protein expression of peroxiredoxin I and II by benzo(a)pyrene and quercetin treatment in 22Rv1 and PrEC prostate cell lines
Amit Chaudhary et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
Differential effects of naturally occurring and synthetic organoselenium compounds on biomarkers in androgen responsive and androgen independent human prostate carcinoma cells
John T. Pinto et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Honokiol, a natural plant product, inhibits the bone metastatic growth of human prostate cancer cells
Katsumi Shigemura et al.
CANCER (2007)
Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells
Emily C. Colgate et al.
CANCER LETTERS (2007)
Putrescine-1,4-dicinnamide from Pholiota spumosa (Basidiomycetes) inhibits cell growth of human prostate cancer cells
A. Russo et al.
PHYTOMEDICINE (2007)
Repression of androgen receptor in prostate cancer cells by phenethyl isothiocyanate
L. G. Wang et al.
CARCINOGENESIS (2006)
Stellettin A induces oxidative stress and apoptosis in HL-60 human leukemia and LNCaP prostate cancer cell lines
W. K. Liu et al.
JOURNAL OF NATURAL PRODUCTS (2006)
Activity-guided isolation of an antiandrogenic compound of Pygeum africanum
Sonja Schleich et al.
PLANTA MEDICA (2006)
The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function
WC Horne et al.
IMMUNOLOGICAL REVIEWS (2005)
Biology of progressive, castration-resistant prostate cancer: Directed therapies targeting the androgen-receptor signaling axis
HI Scher et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak
SV Singh et al.
MOLECULAR CANCER THERAPEUTICS (2005)
Indole-3-carbinol inhibition of androgen receptor expression and downregulation of androgen responsiveness in human prostate cancer cells
JC Hsu et al.
CARCINOGENESIS (2005)
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
SA Tomlins et al.
SCIENCE (2005)
Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer
A Malik et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Induction of apoptosis in prostate cancer cells by pachymic acid from Poria cocos
L Gapter et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer
MA Titus et al.
CLINICAL CANCER RESEARCH (2005)
Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma
M Bonham et al.
CLINICAL CANCER RESEARCH (2005)
Zyflamend (R), a unique herbal preparation with nonselective COX inhibitory activity, induces apoptosis of prostate cancer cells that lack COX-2 expression
DL Bemis et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2005)
Genistein alters growth factor signaling in transgenic prostate model (TRAMP)
J Wang et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2004)
Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: A phase III trial (CALGB 9583)
EJ Small et al.
JOURNAL OF CLINICAL ONCOLOGY (2004)
Overexpression of c-Jun induced by quercetin and resverol inhibits the expression and function of the androgen receptor in human prostate cancer cells
HQ Yuan et al.
CANCER LETTERS (2004)
Molecular determinants of resistance to antiandrogen therapy
CD Chen et al.
NATURE MEDICINE (2004)
The backdoor pathway to dihydrotestosterone
RJ Auchus
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2004)
Investigation of extrinsic and intrinsic apoptosis pathways of new clerodane diterpenoids in human prostate cancer PC-3 cells
DM Huang et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence
E Unni et al.
CANCER RESEARCH (2004)
The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase
L Pintard et al.
NATURE (2003)
BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3
L Xu et al.
NATURE (2003)
Role of p53 and NF-κB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells
K Hastak et al.
ONCOGENE (2003)
Minimal residual disease and trisomy 8
F Pasquali et al.
CANCER GENETICS AND CYTOGENETICS (2003)
Metastasis to bone: Causes, consequences and therapeutic opportunities
GR Mundy
NATURE REVIEWS CANCER (2002)
Infecting one animal with two different strains of the same bacteria may cause misleading results
A Kaygusuz
CHEMOTHERAPY (2002)
Inhibitors of apoptosis proteins in prostate cancer cell lines
KR McEleny et al.
PROSTATE (2002)
The development of androgen-independent prostate cancer
BJ Feldman et al.
NATURE REVIEWS CANCER (2001)
Does the PITSLRE gene complex contribute to the pathogenesis of malignant melanoma of the skin?: A study of patient-derived tumor samples
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CANCER GENETICS AND CYTOGENETICS (2001)
Effects of the flavonoid drug Quercetin on the response of human prostate tumours to hyperthermia in vitro and in vivo
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INTERNATIONAL JOURNAL OF HYPERTHERMIA (2001)
Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival
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GENES & DEVELOPMENT (2001)
Prostate formation in a marsupial is mediated by the testicular androgen 5α-androstane-3α,17β-diol
G Shaw et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Decreased c-Src expression enhances osteoblast differentiation and bone formation
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JOURNAL OF CELL BIOLOGY (2000)