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MOLECULAR CELL (2014)
Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
Huayi Wang et al.
MOLECULAR CELL (2014)
RIPK3 as a potential therapeutic target for Gaucher's disease
Einat B. Vitner et al.
NATURE MEDICINE (2014)
Regulated necrosis: the expanding network of non-apoptotic cell death pathways
Tom Vanden Berghe et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Necroptosis
Andreas Linkermann et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense
Xing Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis
Kim Newton et al.
SCIENCE (2014)
TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species
Francisco J. Roca et al.
CELL (2013)
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis
Sahar A. Saddoughi et al.
EMBO MOLECULAR MEDICINE (2013)
Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL
William J. Kaiser et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis
Jixi Li et al.
CELL (2012)
The Emerging Importance of Autophagy in Pulmonary Diseases
Kenji Mizumura et al.
CHEST (2012)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome
Linde Duprez et al.
IMMUNITY (2011)
Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
Sudan He et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Autophagy in chronic obstructive pulmonary disease Homeostatic or pathogenic mechanism?
Stefan W. Ryter et al.
AUTOPHAGY (2009)
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
YoungSik Cho et al.
CELL (2009)
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
Sudan He et al.
CELL (2009)
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
Shankar S. Iyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Targeting TNF-alpha: A novel therapeutic approach for asthma
Christopher Brightling et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2008)
Identification of RIP1 kinase as a specific cellular target of necrostatins
Alexei Degterev et al.
NATURE CHEMICAL BIOLOGY (2008)
Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease
Zhi-Hua Chen et al.
PLOS ONE (2008)
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
A Degterev et al.
NATURE CHEMICAL BIOLOGY (2005)
Increased levels of cell death and proliferation in alveolar wall cells in patients with pulmonary emphysema
N Yokohori et al.
CHEST (2004)
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
P Scaffidi et al.
NATURE (2002)