GLP-1 Receptor: A New Target for Sepsis

Patients with sepsis often exhibit hyperglycemia, which increases mortality. glucagon-like peptide-1 receptor agonists (GLP-1RAs) not only regulate blood glucose homeostasis but also improve organ dysfunction, regulate immunity, and control inflammation and other functions in patients with sepsis. Here, we review the possible application of GLP-1RAs in sepsis, to provide a new perspective for the clinical diagnosis and treatment of patients with sepsis complicated with stress hyperglycemia.

Automated summary

GLP-1 receptor agonists can not only regulate blood glucose levels but also improve organ function, regulate immunity, and control inflammation in patients with sepsis. They have potential therapeutic benefits for sepsis patients with stress hyperglycemia.