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EXPERIMENTAL NEUROLOGY (2015)
Flies with Parkinson's disease
Roeland Vanhauwaert et al.
EXPERIMENTAL NEUROLOGY (2015)
Regulation of neuronal communication by G protein-coupled receptors
Yunhong Huang et al.
FEBS LETTERS (2015)
Antagonistic pleiotropic effects of nitric oxide in the pathophysiology of Parkinson's disease
D. Tripathy et al.
FREE RADICAL RESEARCH (2015)
Estrogen receptors in the central nervous system and their implication for dopamine-dependent cognition in females
Anne Almey et al.
HORMONES AND BEHAVIOR (2015)
The Nicotine Metabolite, Cotinine, Alters the Assembly and Trafficking of a Subset of Nicotinic Acetylcholine Receptors
Ashley M. Fox et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3 signaling pathway
Juan Deng et al.
JOURNAL OF NEUROCHEMISTRY (2015)
Striatal cholinergic interneurons and cortico-striatal synaptic plasticity in health and disease
Marc Deffains et al.
MOVEMENT DISORDERS (2015)
The nicotinic cholinergic system function in the human brain
Frauke Nees
NEUROPHARMACOLOGY (2015)
Caregiver report of apathy predicts dementia in Parkinson's disease
Whitney Fitts et al.
PARKINSONISM & RELATED DISORDERS (2015)
Nicotinic ACh receptors as therapeutic targets in CNS disorders
Kelly T. Dineley et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2015)
Striatal Cholinergic Interneurons Control Motor Behavior and Basal Ganglia Function in Experimental Parkinsonism
Nicolas Maurice et al.
CELL REPORTS (2015)
Beneficial effects of nicotine, cotinine and its metabolites as potential agents for Parkinson's disease
George E. Barreto et al.
FRONTIERS IN AGING NEUROSCIENCE (2015)
Dopaminergic Regulation of Striatal Interneurons in Reward and Addiction: Focus on Alcohol
Rhona Clarke et al.
NEURAL PLASTICITY (2015)
A novel compound VSC2 has anti-inflammatory and antioxidant properties in microglia and in Parkinson's disease animal model
Ji Ae Lee et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Resting-state functional connectivity associated with mild cognitive impairment in Parkinson's disease
Marianna Amboni et al.
JOURNAL OF NEUROLOGY (2015)
New Insights into the Mechanisms of Action of Cotinine and its Distinctive Effects from Nicotine
J. Alex Grizzell et al.
NEUROCHEMICAL RESEARCH (2015)
Is Cell Death Primary or Secondary in the Pathophysiology of Idiopathic Parkinson's Disease?
Walter J. Schulz-Schaeffer
BIOMOLECULES (2015)
R-(+) and S-(-) Isomers of Cotinine Augment Cholinergic Responses In Vitro and In Vivo
Alvin V. Terry et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Psychiatric aspects of Parkinson's disease
Sandeep Grover et al.
JOURNAL OF NEUROSCIENCES IN RURAL PRACTICE (2015)
Cotinine reduces depressive-like behavior, working memory deficits, and synaptic loss associated with chronic stress in mice
J. Alex Grizzell et al.
BEHAVIOURAL BRAIN RESEARCH (2014)
Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer's disease
Jie Gao et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Cholinergic System Dysfunction and Neurodegenerative Diseases: Cause or Effect?
Ada M. Tata et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2014)
Lithium stimulates human bone marrow derived mesenchymal stem cell proliferation through GSK-3β-dependent β-catenin/Wnt pathway activation
Zhenzhong Zhu et al.
FEBS JOURNAL (2014)
α7 nicotinic acetylcholine receptors control cytochrome c release from isolated mitochondria through kinase-mediated pathways
Galyna Gergalova et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2014)
Mitochondria express several nicotinic acetylcholine receptor subtypes to control various pathways of apoptosis induction
Olena Lykhmus et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2014)
Intracellular localization of the M1 muscarinic acetylcholine receptor through clathrin-dependent constitutive internalization is mediated by a C-terminal tryptophan-based motif
Junsuke Uwada et al.
JOURNAL OF CELL SCIENCE (2014)
A Major External Source of Cholinergic Innervation of the Striatum and Nucleus Accumbens Originates in the Brainstem
Daniel Dautan et al.
JOURNAL OF NEUROSCIENCE (2014)
Downregulation of the Wnt/β-catenin signaling pathway is involved in manganese-induced neurotoxicity in rat striatum and PC12 cells
Junkang Jiang et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2014)
The Parkinsonian mimetic, 6-OHDA, impairs axonal transport in dopaminergic axons
Xi Lu et al.
MOLECULAR NEURODEGENERATION (2014)
Muscarinic acetylcholine receptors: novel opportunities for drug development
Andrew C. Kruse et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
PRIMARY CULTURES OF RAT CORTICAL MICROGLIA TREATED WITH NICOTINE INCREASES IN THE EXPRESSION OF EXCITATORY AMINO ACID TRANSPORTER 1 (GLAST) VIA THE ACTIVATION OF THE α7 NICOTINIC ACETYLCHOLINE RECEPTOR
N. Morioka et al.
NEUROSCIENCE (2014)
Wnt/β-Catenin Signaling Is Required to Rescue Midbrain Dopaminergic Progenitors and Promote Neurorepair in Ageing Mouse Model of Parkinson's Disease
Francesca L'Episcopo et al.
STEM CELLS (2014)
M1 muscarinic acetylcholine receptor in Alzheimer's disease
Shangtong Jiang et al.
NEUROSCIENCE BULLETIN (2014)
Cotinine halts the advance of Alzheimer's disease-like pathology and associated depressive-like behavior in Tg6799 mice
Sagar Patel et al.
FRONTIERS IN AGING NEUROSCIENCE (2014)
A mouse model of non-motor symptoms in Parkinson's disease: focus on pharmacological interventions targeting affective dysfunctions
Alessandra Bonito-Oliva et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2014)
Multiple CNS nicotinic receptors mediate L-dopa-induced dyskinesias: Studies with parkinsonian nicotinic receptor knockout mice
Maryka Quik et al.
BIOCHEMICAL PHARMACOLOGY (2013)
α-Synuclein: The Long Distance Runner
Sonia George et al.
BRAIN PATHOLOGY (2013)
Effect of Nicotine on the Pharmacokinetics of Levodopa
Win Thiri Kyaw et al.
CLINICAL NEUROPHARMACOLOGY (2013)
Midbrain dopaminergic neurons: A review of the molecular circuitry that regulates their development
Shane V. Hegarty et al.
DEVELOPMENTAL BIOLOGY (2013)
Axon degeneration in Parkinson's disease
Robert E. Burke et al.
EXPERIMENTAL NEUROLOGY (2013)
Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism
Manindra Nath Tiwari et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Parkinson disease: from pathology to molecular disease mechanisms
David T. Dexter et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Cotinine and Blood Pressure Levels: Variability Omitted Once Again
Costas Thomopoulos et al.
HYPERTENSION (2013)
α-Synuclein Oligomers Impair Neuronal Microtubule-Kinesin Interplay
Iryna Prots et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Mood disturbances and cognitive functioning in Parkinson's disease: The effects of disease duration and side of onset of motor symptoms
Paul S. Foster et al.
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY (2013)
Novel contribution of cell surface and intracellular M1-muscarinic acetylcholine receptors to synaptic plasticity in hippocampus
Abu Syed Md Anisuzzaman et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Direct and GABA-mediated indirect effects of nicotinic ACh receptor agonists on striatal neurones
Ruixi Luo et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Functional roles of neurotransmitters and neuromodulators in the dorsal striatum
Jeehaeh Do et al.
LEARNING & MEMORY (2013)
Comparison of subcellular distribution and functions between exogenous and endogenous M1 muscarinic acetylcholine receptors
Shigeru Morishima et al.
LIFE SCIENCES (2013)
Nicotine Reduces Established Levodopa-induced Dyskinesias in a Monkey Model of Parkinson's Disease
Maryka Quik et al.
MOVEMENT DISORDERS (2013)
Neuroactive effects of cotinine on the hippocampus: Behavioral and biochemical parameters
R. B. de Aguiar et al.
NEUROPHARMACOLOGY (2013)
Uncoupling of M1 muscarinic receptor/G-protein interaction by amyloid β1-42
Helena Janickova et al.
NEUROPHARMACOLOGY (2013)
Association of nicotine dependence susceptibility gene, CHRNA5, with Parkinson's disease age at onset: Gene and smoking status interaction
Lior Greenbaum et al.
PARKINSONISM & RELATED DISORDERS (2013)
Mitochondrial dysfunction and oxidative stress in Parkinson's disease
Sudhakar Raja Subramaniam et al.
PROGRESS IN NEUROBIOLOGY (2013)
Nicotinic Receptor Agonists Reduce L-DOPA-Induced Dyskinesias in a Monkey Model of Parkinson's Disease
Danhui Zhang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2013)
The nicotine metabolite, cotinine, attenuates glutamate (NMDA) antagonist-related effects on the performance of the five choice serial reaction time task (5C-SRTT) in rats
Alvin V. Terry et al.
BIOCHEMICAL PHARMACOLOGY (2012)
Involvement of store-operated calcium signaling in EGF-mediated COX-2 gene activation in cancer cells
Jaw-Yuan Wang et al.
CELLULAR SIGNALLING (2012)
The Role of Natural Products in the Discovery of New Drug Candidates for the Treatment of Neurodegenerative Disorders I: Parkinsons Disease
Helineide Cristina Campos et al.
CNS & Neurological Disorders-Drug Targets (2012)
Cotinine: A Potential New Therapeutic Agent against Alzheimer's disease
Valentina Echeverria et al.
CNS NEUROSCIENCE & THERAPEUTICS (2012)
α7 Nicotinic Acetylcholine Receptor Mediated Neuroprotection in Parkinson's Disease
Jun Kawamata et al.
CURRENT DRUG TARGETS (2012)
α7 Nicotinic Acetylcholine Receptor Subunit in Angiogenesis and Epithelial to Mesenchymal Transition
Smitha Pillai et al.
CURRENT DRUG TARGETS (2012)
Stress, depression and Parkinson's disease
Ann M. Hemmerle et al.
EXPERIMENTAL NEUROLOGY (2012)
Basal ganglia output to the PPN, a commentary
John F. Stein et al.
EXPERIMENTAL NEUROLOGY (2012)
a-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: relevance to human synucleopathic diseases
Zane S. Martin et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Role of Serotonergic 1A Receptor Dysfunction in Depression Associated with Parkinson's Disease
Benedicte Ballanger et al.
MOVEMENT DISORDERS (2012)
GABAergic circuits mediate the reinforcement-related signals of striatal cholinergic interneurons
Daniel F. English et al.
NATURE NEUROSCIENCE (2012)
Mitochondrial CB1 receptors regulate neuronal energy metabolism
Giovanni Benard et al.
NATURE NEUROSCIENCE (2012)
Neurochemistry and the non-motor aspects of PD
I. Ferrer et al.
NEUROBIOLOGY OF DISEASE (2012)
Increased Oxidative Damage and Decreased Antioxidant Function in Aging Human Substantia Nigra Compared to Striatum: Implications for Parkinson's Disease
C. Venkateshappa et al.
NEUROCHEMICAL RESEARCH (2012)
A Feud that Wasn't: Acetylcholine Evokes Dopamine Release in the Striatum
D. James Surmeier et al.
NEURON (2012)
Striatal Dopamine Release Is Triggered by Synchronized Activity in Cholinergic Interneurons
Sarah Threlfell et al.
NEURON (2012)
Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior
Marina R. Picciotto et al.
NEURON (2012)
Role for α6 nicotinic receptors in L-dopa-induced dyskinesias in parkinsonian mice
Maryka Quik et al.
NEUROPHARMACOLOGY (2012)
Cellular and molecular mechanisms of antioxidants in Parkinson's disease
Jhon Jairo Sutachan et al.
NUTRITIONAL NEUROSCIENCE (2012)
Cholinergic modulation of food and drug satiety and withdrawal
Nicole M. Avena et al.
PHYSIOLOGY & BEHAVIOR (2012)
Non-Motor Symptoms in Patients with Parkinson's Disease - Correlations with Inflammatory Cytokines in Serum
Daniel Lindqvist et al.
PLOS ONE (2012)
Mitochondrial Biology and Parkinson's Disease
Celine Perier et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Cotinine: beyond that expected, more than a biomarker of tobacco consumption
Valentina Echeverria Moran
FRONTIERS IN PHARMACOLOGY (2012)
Modulation of Striatal Projection Systems by Dopamine
Charles R. Gerfen et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 34 (2011)
Single-Cell Redox Imaging Demonstrates a Distinctive Response of Dopaminergic Neurons to Oxidative Insults
Maxx P. Horowitz et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
The cholinergic system and neostriatal memory functions
Robbert Havekes et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
The cerebrovascular role of the cholinergic neural system in Alzheimer's disease
Arenda H. E. A. Van Beek et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
Involvement of the cholinergic system in conditioning and perceptual memory
Lianne Robinson et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
The cholinergic system and Parkinson disease
Nicolaas I. Bohnen et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
Naturally-expressed nicotinic acetylcholine receptor subtypes
Jie Wu et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Modulation of Tau Phosphorylation by the Kinase PKR: Implications in Alzheimer's Disease
Anindita Bose et al.
BRAIN PATHOLOGY (2011)
Targeting Nicotinic Receptors for Parkinson's Disease Therapy
Maryka Quik et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2011)
Monoamine Oxidase B Inhibitors for the Treatment of Parkinson's Disease A Review of Symptomatic and Potential Disease-Modifying Effects
Anthony H. V. Schapira
CNS DRUGS (2011)
Cholinergic modulation of synaptic integration and dendritic excitability in the striatum
Ian Anton Oldenburg et al.
CURRENT OPINION IN NEUROBIOLOGY (2011)
Epidemiology and etiology of Parkinson's disease: a review of the evidence
Karin Wirdefeldt et al.
EUROPEAN JOURNAL OF EPIDEMIOLOGY (2011)
Differential effects of subtype-specific nicotinic acetylcholine receptor agonists on early and late hippocampal LTP
Katja S. Kroker et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Neuroprotection of midbrain dopamine neurons by nicotine is gated by cytoplasmic Ca2+
Damien Toulorge et al.
FASEB JOURNAL (2011)
Cotinine Reduces Amyloid-beta Aggregation and Improves Memory in Alzheimer's Disease Mice
Valentina Echeverria et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Stimulating Nicotinic Receptors Trigger Multiple Pathways Attenuating Cytotoxicity in Models of Alzheimer's and Parkinson's Diseases
Jun Kawamata et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Dopamine D1-histamine H3 Receptor Heteromers Provide a Selective Link to MAPK Signaling in GABAergic Neurons of the Direct Striatal Pathway
Estefana Moreno et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Serotonin innervation of basal ganglia in monkeys and humans
Martin Parent et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2011)
Nicotine up-regulates alpha 4 beta 2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning
Rahul Srinivasan et al.
JOURNAL OF GENERAL PHYSIOLOGY (2011)
Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease
Isidre Ferrer et al.
JOURNAL OF NEURAL TRANSMISSION (2011)
The Distinct Role of Medium Spiny Neurons and Cholinergic Interneurons in the D2/A2A Receptor Interaction in the Striatum: Implications for Parkinson's Disease
Alessandro Tozzi et al.
JOURNAL OF NEUROSCIENCE (2011)
Nicotine Reduces L-DOPA-Induced Dyskinesias by Acting at β2*Nicotinic Receptors
Luping Z. Huang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Environmental tobacco smoke and Parkinson's disease
Susan Searles Nielsen et al.
MOVEMENT DISORDERS (2011)
Etiology and Pathogenesis of Parkinson's Disease
Anthony H. Schapira et al.
MOVEMENT DISORDERS (2011)
Chronic nicotine restores normal Aβ levels and prevents short-term memory and E-LTP impairment in Aβ rat model of Alzheimer's disease
Marisa Srivareerat et al.
NEUROBIOLOGY OF AGING (2011)
Ethanol-induced modulation of synaptic output from the dorsolateral striatum in rat is regulated by cholinergic interneurons
Louise Adermark et al.
NEUROCHEMISTRY INTERNATIONAL (2011)
Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian rats
Luping Z. Huang et al.
NEUROPHARMACOLOGY (2011)
Muscarinic Receptor Occupancy and Cognitive Impairment: A PET Study with [11C](+)3-MPB and Scopolamine in Conscious Monkeys
Shigeyuki Yamamoto et al.
NEUROPSYCHOPHARMACOLOGY (2011)
SPONTANEOUS FIRING AND EVOKED PAUSES IN THE TONICALLY ACTIVE CHOLINERGIC INTERNEURONS OF THE STRIATUM
J. A. Goldberg et al.
NEUROSCIENCE (2011)
Serotonergic action on dorsal striatal function
Brian N. Mathur et al.
PARKINSONISM & RELATED DISORDERS (2011)
α6β2*and α4β2*Nicotinic Acetylcholine Receptors As Drug Targets for Parkinson's Disease
Maryka Quik et al.
PHARMACOLOGICAL REVIEWS (2011)
Striatal origin of the pathologic beta oscillations in Parkinson's disease
M. M. McCarthy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Cholinergic receptor subtypes and their role in cognition, emotion, and vigilance control: An overview of preclinical and clinical findings
Susanne Graef et al.
PSYCHOPHARMACOLOGY (2011)
Targeting neuronal populations of the striatum
Pierre F. Durieux et al.
FRONTIERS IN NEUROANATOMY (2011)
Centrality of striatal cholinergic transmission in basal ganglia function
Paola Bonsi et al.
FRONTIERS IN NEUROANATOMY (2011)
Enhancement of nicotinic receptors alleviates cytotoxicity in neurological disease models
Jun Kawamata et al.
THERAPEUTIC ADVANCES IN CHRONIC DISEASE (2011)
Mitochondrial Dysfunction in Parkinson's Disease
P. C. Keane et al.
PARKINSONS DISEASE (2011)
Dopamine signaling in dorsal versus ventral striatum: the dynamic role of cholinergic interneurons
Sarah Threlfell et al.
FRONTIERS IN SYSTEMS NEUROSCIENCE (2011)
Active and passive smoking and risk of Parkinson's disease
K. Tanaka et al.
ACTA NEUROLOGICA SCANDINAVICA (2010)
The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia
Walter J. Schulz-Schaeffer
ACTA NEUROPATHOLOGICA (2010)
Adenosine-cannabinoid receptor interactions. Implications for striatal function
Sergi Ferre et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Acetylcholine-Dopamine Interactions in the Pathophysiology and Treatment of CNS Disorders
Deranda B. Lester et al.
CNS NEUROSCIENCE & THERAPEUTICS (2010)
Depression Impairs Learning Whereas Anticholinergics Impair Transfer Generalization in Parkinson Patients Tested on Dopaminergic Medications
Mohammad M. Herzallah et al.
COGNITIVE AND BEHAVIORAL NEUROLOGY (2010)
Acetylcholine-dopamine balance hypothesis in the striatum: An update
Toshihiko Aosaki et al.
GERIATRICS & GERONTOLOGY INTERNATIONAL (2010)
Kinetics of PIP2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells
Bjoern H. Falkenburger et al.
JOURNAL OF GENERAL PHYSIOLOGY (2010)
Striatal Muscarinic Receptors Promote Activity Dependence of Dopamine Transmission via Distinct Receptor Subtypes on Cholinergic Interneurons in Ventral versus Dorsal Striatum
Sarah Threlfell et al.
JOURNAL OF NEUROSCIENCE (2010)
Nicotinic Receptor-Mediated Reduction in L-DOPA-Induced Dyskinesias May Occur via Desensitization
Tanuja Bordia et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Midbrain SERT in Degenerative Parkinsonisms: A 123I-FP-CIT SPECT Study
Francesco Roselli et al.
MOVEMENT DISORDERS (2010)
Smoking duration, intensity, and risk of Parkinson disease
H. Chen et al.
NEUROLOGY (2010)
PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson's Disease
Bin Zheng et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
Modulation of the activity of dopaminergic neurons by SK channels: a potential target for the treatment of Parkinson's disease?
Xiao-Kun Liu et al.
NEUROSCIENCE BULLETIN (2010)
Nicotine is a Selective Pharmacological Chaperone of Acetylcholine Receptor Number and Stoichiometry. Implications for Drug Discovery
Henry A. Lester et al.
AAPS JOURNAL (2009)
Olfactory bulb α-synucleinopathy has high specificity and sensitivity for Lewy body disorders
Thomas G. Beach et al.
ACTA NEUROPATHOLOGICA (2009)
Nicotinic acetylcholine receptors and the ascending dopamine pathways
Phil D. Livingstone et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Multiple roles for nicotine in Parkinson's disease
Maryka Quik et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Structural and functional diversity of native brain neuronal nicotinic receptors
Cecilia Gotti et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Smoking and Parkinson's disease: Does nicotine affect α-synuclein fibrillation?
Dong-Pyo Hong et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2009)
Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation
Rodrigo R. Resende et al.
CELL COMMUNICATION AND SIGNALING (2009)
Intracellular Metabotropic Glutamate Receptor 5 (mGluR5) Activates Signaling Cascades Distinct from Cell Surface Counterparts
Yuh-Jiin I. Jong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys
Luping Z. Huang et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Contrasting Effects of Allosteric and Orthosteric Agonists on M-1 Muscarinic Acetylcholine Receptor Internalization and Down-regulation
Rachel L. Thomas et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Does smoking reduce the risk of Parkinson's disease through stimulation of the ubiquitin-proteasome system?
Mary Ann Chapman
MEDICAL HYPOTHESES (2009)
History of falls in Parkinson disease is associated with reduced cholinergic activity
N. I. Bohnen et al.
NEUROLOGY (2009)
Diversity of vertebrate nicotinic acetylcholine receptors
Neil S. Millar et al.
NEUROPHARMACOLOGY (2009)
Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function
Edson X. Albuquerque et al.
PHYSIOLOGICAL REVIEWS (2009)
Hippocampal atrophy predicts conversion to dementia after STN-DBS in Parkinson's disease
Selma Aybek et al.
PARKINSONISM & RELATED DISORDERS (2009)
Nicotinic Acetylcholine Receptor Signalling: Roles in Alzheimer's Disease and Amyloid Neuroprotection
S. D. Buckingham et al.
PHARMACOLOGICAL REVIEWS (2009)
Enduring involvement of tau, β-amyloid, α-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam (ALS/PDC)
Judith Miklossy et al.
ACTA NEUROPATHOLOGICA (2008)
Cotinine-induced convergence of the cholinergic and PI3 kinase-dependent anti-inflammatory pathways in innate immune cells
Kunal Rehani et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1
C. J. Langmead et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
Latha Devi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Striatal β-amyloid deposition in Parkinson disease with dementia
Michail E. Kalaitzakis et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
Recurrent collateral connections of striatal medium spiny neurons are disrupted in models of Parkinson's disease
Stefano Taverna et al.
JOURNAL OF NEUROSCIENCE (2008)
Cotinine selectively activates a Subpopulation of α3/α6β2*nicotinic receptors in monkey striatum
Kathryn O'Leary et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Continuous and intermittent nicotine treatment reduces L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesias in a rat model of Parkinson's disease
Tanuja Bordia et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
G protein-coupled receptors in and on the cell nucleus: A new signaling paradigm?
Benoit Boivin et al.
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2008)
Chronic nicotine exposure induces a long-lasting and pathway-specific facilitation of LTP in the amygdala
Yan-You Huang et al.
LEARNING & MEMORY (2008)
Transcriptional regulation of mesencephalic dopaminergic neurons: The full circle of life and death
Kambiz N. Alavian et al.
MOVEMENT DISORDERS (2008)
Striatal Plasticity and Basal Ganglia Circuit Function
Anatol C. Kreitzer et al.
NEURON (2008)
From symphony to cacophony: Pathophysiology of the human basal ganglia in Parkinson disease
John T. Gale et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2008)
Cigarette smoke, nicotine and cotinine protect against 6-hydroxydopamine-induced toxicity in SH-SY5Y cells
Karen Riveles et al.
NEUROTOXICOLOGY (2008)
Muscarinic acetylcholine receptors as CNS drug targets
Christopher J. Langmead et al.
PHARMACOLOGY & THERAPEUTICS (2008)
Reduced striatal tyrosine hydroxylase in incidental Lewy body disease
Thomas Gerald Beach et al.
ACTA NEUROPATHOLOGICA (2008)
The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation
W. J. de Jonge et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Nicotinic receptors as CNS targets for Parkinson's disease
Maryka Quik et al.
BIOCHEMICAL PHARMACOLOGY (2007)
Parkinson's disease
Bobby Thomas et al.
HUMAN MOLECULAR GENETICS (2007)
Clinical diagnostic criteria for dementia associated with Parkinson's disease
Murat Emre et al.
MOVEMENT DISORDERS (2007)
Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action
Hyun Jung Park et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Application of nicotine enantiomers, derivatives and analogues in therapy of neurodegenerative disorders
Dariusz Pogocki et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Dopamine neuron systems in the brain:: an update
Anders Bjorklund et al.
TRENDS IN NEUROSCIENCES (2007)
Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease
David Sulzer
TRENDS IN NEUROSCIENCES (2007)
Cholinergic interneurons control the excitatory input to the striatum
Pavel Pakhotin et al.
JOURNAL OF NEUROSCIENCE (2007)
Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms
G. Mudo et al.
JOURNAL OF NEURAL TRANSMISSION (2007)
Basal ganglia macrocircuits
J. M. Tepper et al.
GABA AND THE BASAL GANGLIA: FROM MOLECULES TO SYSTEMS (2007)
Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development
Juergen Wess et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Nicotinic acetylcholine receptors on basophils and mast cells
P. S. Sudheer et al.
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Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates
Maryka Quik et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Striatal α6* nicotinic acetylcholine receptors:: Potential targets for Parkinson's disease therapy
M Quik et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
α7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal UP induction in β-amyloid infused rats
L Chen et al.
NEUROPHARMACOLOGY (2006)
Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival
J Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection
CY Chung et al.
HUMAN MOLECULAR GENETICS (2005)
Cognitive status correlates with neuropathologic stage in Parkinson disease
H Braak et al.
NEUROLOGY (2005)
Smoking, nicotine and Parkinson's disease
M Quik
TRENDS IN NEUROSCIENCES (2004)
Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons
GM Leinninger et al.
FASEB JOURNAL (2004)
Beta-secretase BACE1 is differentially controlled through muscarinic acetylcholine receptor signaling
T Züchner et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2004)
Nicotinic acetylcholine receptor distribution in Alzheimer's disease, dementia with lewy bodies, Parkinson's disease, and vascular dementia: In vitro binding study using 5-[I-125]-A-85380
SL Pimlott et al.
NEUROPSYCHOPHARMACOLOGY (2004)
M1 muscarinic receptor activation protects neurons from β-amyloid toxicity.: A role for Wnt signaling pathway
GG Farías et al.
NEUROBIOLOGY OF DISEASE (2004)
Nicotinic acetylcholine receptors and the regulation of neuronal signalling
F Dajas-Bailador et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2004)
The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives for MAPK-dependent amyloid precursor protein processing
M Yogev-Falach et al.
FASEB JOURNAL (2003)
Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines
MV Skok et al.
MOLECULAR PHARMACOLOGY (2003)
Cotinine inhibits catecholamine release evoked by cholinergic stimulation from the rat adrenal medulla
YY Koh et al.
ARCHIVES OF PHARMACAL RESEARCH (2003)
Prenatal exposure to the bacteriotoxin lipopolysaccharide leads to long-term losses of dopamine neurons in offspring: A potential, new model of Parkinson's disease
PM Carvey et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2003)
Assembly and subunit diversity of nicotinic acetylcholine receptors
NS Millar
BIOCHEMICAL SOCIETY TRANSACTIONS (2003)
The potential role of cotinine in the cognitive and neuroprotective actions of nicotine
JJ Buccafusco et al.
LIFE SCIENCES (2003)
Prevalence and characteristics of dementia in Parkinson disease - An 8-year prospective study
D Aarsland et al.
ARCHIVES OF NEUROLOGY (2003)
Muscarinic and nicotinic cholinergic mechanisms in the mesostriatal dopamine systems
FM Zhou et al.
NEUROSCIENTIST (2003)
Cognitive impairments in advanced PD without dementia
J Green et al.
NEUROLOGY (2002)
Nicotine and nicotinic receptors; Relevance to Parkinson's disease
M Quik et al.
NEUROTOXICOLOGY (2002)
The genetic basis of Parkinson's disease
T Foltynie et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2002)
Non-steroidal anti-inflammatory drugs stimulate secretion of non-amyloidogenic precursor protein
Y Avramovich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Effects of (-)-nicotine and (-)-cotinine on 6-hydroxydopamine-induced oxidative stress and neurotoxicity:: relevance for Parkinson's disease
R Soto-Otero et al.
BIOCHEMICAL PHARMACOLOGY (2002)
The heterogeneity of idiopathic Parkinson's disease
T Foltynie et al.
JOURNAL OF NEUROLOGY (2002)
Direct evidence that release-stimulating alpha 7*nicotinic cholinergic receptors are localized on human and rat brain glutamatergic axon terminals
M Marchi et al.
JOURNAL OF NEUROCHEMISTRY (2002)
α7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block a β-amyloid-induced neurotoxicity
T Kihara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Nicotine, but not cotinine, partially protects dopaminergic neurons against MPTP-induced degeneration in mice
K Parain et al.
BRAIN RESEARCH (2001)
Intrinsic membrane properties underlying spontaneous tonic firing in neostriatal cholinergic interneurons
BD Bennett et al.
JOURNAL OF NEUROSCIENCE (2000)
α-Bungarotoxin-sensitive nicotinic receptors indirectly modulate [3H]dopamine release in rat striatal slices via glutamate release
S Kaiser et al.
MOLECULAR PHARMACOLOGY (2000)
Synaptic organisation of the basal ganglia
JP Bolam et al.
JOURNAL OF ANATOMY (2000)
Nicotinic receptors in the brain: Links between molecular biology and behavior
MR Picciotto et al.
NEUROPSYCHOPHARMACOLOGY (2000)
Nicotine binding in human striatum: Elevation in schizophrenia and reductions in dementia with Lewy bodies, Parkinson's disease and Alzheimer's disease and in relation to neuroleptic medication
JA Court et al.
NEUROSCIENCE (2000)